hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11269.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNC4 | Potassium voltage-gated channel subfamily C member 4 (KSHIIIC) (Voltage-gated potassium channel subunit Kv3.4) | 5 | UniProt NCBI |
| KCNC1 | Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) | 5 | UniProt NCBI |
| KCNC3 | Potassium voltage-gated channel subfamily C member 3 (KSHIIID) (Voltage-gated potassium channel subunit Kv3.3) | 5 | UniProt NCBI |
| PAX6 | Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin) | 5 | UniProt NCBI |
| TNS1 | Tensin-1 (EC 3.1.3.-) | 5 | UniProt NCBI |
| DCAF4L2 | DDB1- and CUL4-associated factor 4-like protein 2 (WD repeat-containing protein 21C) | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296072 | 8.09488316343e-06 | 0.6 | KCNC4 KCNC3 KCNC1 | Voltage gated Potassium channels |
| REAC:R-HSA-1296071 | 0.000141884912451 | 0.6 | KCNC4 KCNC3 KCNC1 | Potassium Channels |
| GO:0032809 | 0.000652677252708 | 0.6 | KCNC4 KCNC3 KCNC1 | neuronal cell body membrane |
| GO:0005251 | 0.000783132248318 | 0.6 | KCNC4 KCNC3 KCNC1 | delayed rectifier potassium channel activity |
| GO:0032590 | 0.000929874009882 | 0.6 | KCNC4 KCNC3 KCNC1 | dendrite membrane |
| GO:0044298 | 0.000929874009882 | 0.6 | KCNC4 KCNC3 KCNC1 | cell body membrane |
| GO:0032589 | 0.00194127795747 | 0.6 | KCNC4 KCNC3 KCNC1 | neuron projection membrane |
| GO:0042734 | 0.0094606249379 | 0.6 | KCNC4 KCNC3 KCNC1 | presynaptic membrane |
| REAC:R-HSA-112316 | 0.0132169246876 | 0.6 | KCNC4 KCNC3 KCNC1 | Neuronal System |
| GO:0043679 | 0.0155155487472 | 0.6 | KCNC4 KCNC3 KCNC1 | axon terminus |
| GO:0005249 | 0.018748745536 | 0.6 | KCNC4 KCNC3 KCNC1 | voltage-gated potassium channel activity |
| GO:0008076 | 0.0237169649094 | 0.6 | KCNC4 KCNC3 KCNC1 | voltage-gated potassium channel complex |
| GO:0044306 | 0.0264997162634 | 0.6 | KCNC4 KCNC3 KCNC1 | neuron projection terminus |
| GO:0005267 | 0.0343879535233 | 0.6 | KCNC4 KCNC3 KCNC1 | potassium channel activity |
| GO:0034705 | 0.0343879535233 | 0.6 | KCNC4 KCNC3 KCNC1 | potassium channel complex |
| GO:0045211 | 0.0437005530348 | 0.6 | KCNC4 KCNC3 KCNC1 | postsynaptic membrane |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| KCNC3 | KCNC4 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| KCNC3 | TNS1 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KCNC4 | DCAF4L2 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KCNC1 | KCNC4 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KCNC3 | PAX6 | 0.984 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| KCNC1 | KCNC3 | 0.976 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| TNS1 | KCNC4 | 0.902 | bioplex3_WMM WMM_only | |
| KCNC1 | DCAF4L2 | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | |
| KCNC3 | DCAF4L2 | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | |
| KCNC1 | PAX6 | 0.278 | bioplex3_WMM WMM_only | |
| PAX6 | KCNC4 | 0.278 | bioplex3_WMM WMM_only | |
| TNS1 | PAX6 | 0.214 | bioplex3_WMM WMM_only | |
| KCNC1 | TNS1 | 0.214 | bioplex3_WMM WMM_only |
Related Complexes