hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11301.1
Complex Portal: CPX-13647
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FOXE3 | Forkhead box protein E3 (Forkhead-related protein FKHL12) (Forkhead-related transcription factor 8) (FREAC-8) | 5 | UniProt NCBI |
| SP140L | Nuclear body protein SP140-like protein | 3 | UniProt NCBI |
| HES6 | Transcription cofactor HES-6 (C-HAIRY1) (Class B basic helix-loop-helix protein 41) (bHLHb41) (Hairy and enhancer of split 6) | 5 | UniProt NCBI |
| KLF13 | Krueppel-like factor 13 (Basic transcription element-binding protein 3) (BTE-binding protein 3) (Novel Sp1-like zinc finger transcription factor 1) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor BTEB3) (Transcription factor NSLP1) | 5 | UniProt NCBI |
| TNFSF12 | Tumor necrosis factor ligand superfamily member 12 (APO3 ligand) (TNF-related weak inducer of apoptosis) (TWEAK) [Cleaved into: Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form] | 5 | UniProt NCBI |
| HOXA9 | Homeobox protein Hox-A9 (Homeobox protein Hox-1G) | 5 | UniProt NCBI |
| HES1 | Transcription factor HES-1 (Class B basic helix-loop-helix protein 39) (bHLHb39) (Hairy and enhancer of split 1) (Hairy homolog) (Hairy-like protein) (hHL) | 5 | UniProt NCBI |
| CHCHD2 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (Aging-associated gene 10 protein) (HCV NS2 trans-regulated protein) (NS2TP) | 5 | UniProt NCBI |
| FBXO33 | F-box only protein 33 | 3 | UniProt NCBI |
| GPATCH2L | G patch domain-containing protein 2-like | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP61 | 0.0386378382776 | 0.2 | HES6 HES1 | Notch signaling pathway |
| CORUM:4090 | 0.0499436884912 | 0.1 | HOXA9 | SMAD6-HOXA9 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HES1 | HES6 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SP140L | CHCHD2 | 0.992 | 0.024 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GPATCH2L | CHCHD2 | 0.992 | 0.082 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CHCHD2 | HES6 | 0.988 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| HOXA9 | CHCHD2 | 0.98 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KLF13 | CHCHD2 | 0.979 | 0.074 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FBXO33 | CHCHD2 | 0.942 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KLF13 | HES6 | 0.904 | bioplex3_WMM WMM_only | ||
| KLF13 | GPATCH2L | 0.904 | 0.102 | bioplex3_WMM WMM_only | |
| KLF13 | SP140L | 0.902 | 0.046 | bioplex3_WMM WMM_only | |
| SP140L | HES6 | 0.902 | bioplex3_WMM WMM_only | ||
| FBXO33 | SP140L | 0.902 | bioplex3_WMM WMM_only | ||
| HOXA9 | SP140L | 0.902 | bioplex3_WMM WMM_only | ||
| GPATCH2L | SP140L | 0.902 | 0.054 | bioplex3_WMM WMM_only | |
| KLF13 | HOXA9 | 0.892 | bioplex3_WMM WMM_only | ||
| GPATCH2L | HES6 | 0.869 | bioplex3_WMM WMM_only | ||
| CHCHD2 | TNFSF12 | 0.838 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CHCHD2 | FOXE3 | 0.826 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| GPATCH2L | HOXA9 | 0.768 | bioplex3_WMM WMM_only | ||
| HOXA9 | HES6 | 0.768 | bioplex3_WMM WMM_only | ||
| KLF13 | FBXO33 | 0.768 | bioplex3_WMM WMM_only | ||
| GPATCH2L | FBXO33 | 0.73 | bioplex3_WMM WMM_only | ||
| FBXO33 | HES6 | 0.73 | bioplex3_WMM WMM_only | ||
| HOXA9 | FBXO33 | 0.73 | bioplex3_WMM WMM_only |
Related Complexes