hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11306.1
Complex Portal: CPX-12148
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NOL4L | Nucleolar protein 4-like | 3 | UniProt NCBI |
| NCKAP5L | Nck-associated protein 5-like (NCKAP5-like) (Centrosomal protein of 169 kDa) (Cep169) | 5 | UniProt NCBI |
| PRDM2 | PR domain zinc finger protein 2 (EC 2.1.1.355) (GATA-3-binding protein G3B) (Lysine N-methyltransferase 8) (MTB-ZF) (MTE-binding protein) (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc finger protein) (Zinc finger protein RIZ) | 5 | UniProt NCBI |
| MYT1 | Myelin transcription factor 1 (MyT1) (Myelin transcription factor I) (MyTI) (PLPB1) (Proteolipid protein-binding protein) | 5 | UniProt NCBI |
| CTBP1 | C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) | 5 | UniProt NCBI |
| LCORL | Ligand-dependent nuclear receptor corepressor-like protein (LCoR-like protein) | 4 | UniProt NCBI |
| NOL4 | Nucleolar protein 4 (Nucleolar-localized protein) | 5 | UniProt NCBI |
| ZEB1 | Zinc finger E-box-binding homeobox 1 (NIL-2-A zinc finger protein) (Negative regulator of IL2) (Transcription factor 8) (TCF-8) | 5 | UniProt NCBI |
| ZEB2 | Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (SMADIP1) (Zinc finger homeobox protein 1b) | 5 | UniProt NCBI |
| DMRTB1 | Doublesex- and mab-3-related transcription factor B1 | 4 | UniProt NCBI |
| TEX9 | Testis-expressed protein 9 | 3 | UniProt NCBI |
| ZNF536 | Zinc finger protein 536 | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:642 | 1.73805666281e-05 | 0.25 | ZEB1 CTBP1 ZEB2 | CtBP complex |
| HP:0009918 | 0.00049829695005 | 0.25 | ZEB1 CTBP1 ZEB2 | Ectopia pupillae |
| CORUM:643 | 0.00134902339898 | 0.166666666667 | ZEB1 CTBP1 | CtBP core complex |
| HP:0000615 | 0.0139557830468 | 0.25 | ZEB1 CTBP1 ZEB2 | Abnormal pupil morphology |
| MIRNA:mmu-miR-200a-3p | 0.0309012475255 | 0.166666666667 | ZEB1 ZEB2 | mmu-miR-200a-3p |
| MIRNA:mmu-miR-200b-3p | 0.0309012475255 | 0.166666666667 | ZEB1 ZEB2 | mmu-miR-200b-3p |
| MIRNA:mmu-miR-200c-3p | 0.0309012475255 | 0.166666666667 | ZEB1 ZEB2 | mmu-miR-200c-3p |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NOL4L | TEX9 | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| NOL4 | TEX9 | 0.985 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| LCORL | CTBP1 | 0.984 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF536 | CTBP1 | 0.973 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | ||
| NOL4L | NOL4 | 0.969 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| ZEB2 | CTBP1 | 0.956 | 0.108 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| NOL4 | NCKAP5L | 0.954 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| LCORL | NOL4 | 0.951 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| CTBP1 | DMRTB1 | 0.926 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | ||
| CTBP1 | NOL4L | 0.926 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM treiber_WMM | ||
| CTBP1 | NOL4 | 0.895 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CTBP1 | PRDM2 | 0.879 | 0.17 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CTBP1 | ZEB1 | 0.878 | 0.142 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| CTBP1 | MYT1 | 0.871 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | ||
| ZNF536 | ZEB1 | 0.659 | 0.074 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZNF536 | LCORL | 0.612 | 0.03 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF536 | ZEB2 | 0.587 | 0.116 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| NOL4L | ZEB1 | 0.582 | 0.084 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZEB2 | NOL4L | 0.582 | 0.038 | bioplex_WMM bioplex3_WMM WMM_only | |
| NOL4L | PRDM2 | 0.582 | 0.144 | bioplex_WMM bioplex3_WMM WMM_only | |
| LCORL | ZEB1 | 0.582 | 0.144 | bioplex_WMM bioplex3_WMM WMM_only | |
| PRDM2 | ZEB1 | 0.581 | 0.086 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZEB2 | PRDM2 | 0.568 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | |
| LCORL | ZEB2 | 0.568 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| LCORL | PRDM2 | 0.568 | 0.136 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF536 | PRDM2 | 0.557 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZEB2 | NOL4 | 0.535 | 0.084 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| NOL4 | PRDM2 | 0.513 | 0.112 | bioplex_WMM bioplex3_WMM WMM_only | |
| NOL4 | ZEB1 | 0.513 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZEB2 | ZEB1 | 0.509 | 0.052 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZNF536 | NOL4L | 0.502 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF536 | NOL4 | 0.412 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| LCORL | NOL4L | 0.378 | 0.206 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| LCORL | NCKAP5L | 0.274 | 0.116 | bioplex3_WMM WMM_only | |
| LCORL | TEX9 | 0.25 | bioplex3_WMM WMM_only | ||
| NOL4L | NCKAP5L | 0.21 | 0.064 | bioplex3_WMM WMM_only | |
| NCKAP5L | TEX9 | 0.047 | bioplex3_WMM youn_WMM gupta_WMM WMM_only | ||
| CTBP1 | TEX9 | 0.01 | bioplex3_WMM youn_WMM gupta_WMM WMM_only | ||
| ZNF536 | NCKAP5L | 0.004 | 0.082 | youn_WMM gupta_WMM WMM_only | |
| CTBP1 | NCKAP5L | 0.003 | 0.152 | bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes