hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11309.1
Complex Portal: CPX-16419
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MRI1 | Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (Mediator of RhoA-dependent invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein) | 5 | UniProt NCBI |
| UBE2F | NEDD8-conjugating enzyme UBE2F (EC 2.3.2.32) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (RING-type E3 NEDD8 transferase UBE2F) (Ubiquitin-conjugating enzyme E2 F) | 5 | UniProt NCBI |
| CUBN | Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) | 5 | UniProt NCBI |
| ZNF841 | Zinc finger protein 841 | 3 | UniProt NCBI |
| CUL9 | Cullin-9 (CUL-9) (UbcH7-associated protein 1) (p53-associated parkin-like cytoplasmic protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6474 | 0.0498708842806 | 0.2 | CUBN | Cubam complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZNF841 | CUL9 | 0.981 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| UBE2F | CUL9 | 0.98 | 0.066 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MRI1 | CUL9 | 0.965 | 0.1 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CUL9 | CUBN | 0.922 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| UBE2F | ZNF841 | 0.415 | bioplex3_WMM WMM_only | ||
| ZNF841 | CUBN | 0.415 | bioplex3_WMM WMM_only | ||
| UBE2F | CUBN | 0.415 | bioplex3_WMM WMM_only | ||
| MRI1 | CUBN | 0.03 | 0.024 | bioplex3_WMM WMM_only | |
| MRI1 | ZNF841 | 0.03 | bioplex3_WMM WMM_only | ||
| MRI1 | UBE2F | 0.03 | 0.052 | bioplex3_WMM WMM_only |
Related Complexes