hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11321.1
Complex Portal: CPX-17043
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DGKH | Diacylglycerol kinase eta (DAG kinase eta) (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) | 5 | UniProt NCBI |
| DGKG | Diacylglycerol kinase gamma (DAG kinase gamma) (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) | 5 | UniProt NCBI |
| DHTKD1 | 2-oxoadipate dehydrogenase complex component E1 (E1a) (OADC-E1) (OADH-E1) (EC 1.2.4.-) (2-oxoadipate dehydrogenase, mitochondrial) (Alpha-ketoadipate dehydrogenase) (Alpha-KADH-E1) (Dehydrogenase E1 and transketolase domain-containing protein 1) (Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial) | 5 | UniProt NCBI |
| ZC2HC1A | Zinc finger C2HC domain-containing protein 1A | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-114508 | 0.00258893271292 | 0.5 | DGKG DGKH | Effects of PIP2 hydrolysis |
| KEGG:00561 | 0.0034402616107 | 0.5 | DGKG DGKH | Glycerolipid metabolism |
| KEGG:00564 | 0.00767363259098 | 0.5 | DGKG DGKH | Glycerophospholipid metabolism |
| KEGG:05231 | 0.00847251296121 | 0.5 | DGKG DGKH | Choline metabolism in cancer |
| KEGG:04070 | 0.00888666878999 | 0.5 | DGKG DGKH | Phosphatidylinositol signaling system |
| KEGG:04072 | 0.0165563012031 | 0.5 | DGKG DGKH | Phospholipase D signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZC2HC1A | DGKG | 0.987 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| DGKH | DGKG | 0.984 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| DGKG | DHTKD1 | 0.919 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ZC2HC1A | DHTKD1 | 0.093 | 0.034 | bioplex3_WMM WMM_only | |
| DGKH | DHTKD1 | 0.078 | 0.086 | bioplex3_WMM WMM_only | |
| DGKH | ZC2HC1A | 0.078 | 0.102 | bioplex3_WMM WMM_only |
Related Complexes