hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11322.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NUDT10 | Diphosphoinositol polyphosphate phosphohydrolase 3-alpha (DIPP-3-alpha) (DIPP3-alpha) (hDIPP3alpha) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha) (Diadenosine hexaphosphate hydrolase (AMP-forming)) (EC 3.6.1.60) (Nucleoside diphosphate-linked moiety X motif 10) (Nudix motif 10) (hAps2) | 5 | UniProt NCBI |
| NUDT3 | Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1) (EC 3.6.1.52) (Diadenosine hexaphosphate hydrolase) (Ap6A hydrolase) (EC 3.6.1.61) (Endopolyphosphatase) (EC 3.6.1.10) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3) (m7GpppN-mRNA hydrolase) (EC 3.6.1.62) (m7GpppX diphosphatase) (EC 3.6.1.59) | 5 | UniProt NCBI |
| KLF16 | Krueppel-like factor 16 (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor BTEB4) (Transcription factor NSLP2) | 4 | UniProt NCBI |
| NUDT4 | Diphosphoinositol polyphosphate phosphohydrolase 2 (DIPP-2) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2) (Nucleoside diphosphate-linked moiety X motif 4) (Nudix motif 4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1855167 | 1.17833531486e-07 | 0.75 | NUDT10 NUDT3 NUDT4 | Synthesis of pyrophosphates in the cytosol |
| GO:1901911 | 1.53784171933e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | adenosine 5'-(hexahydrogen pentaphosphate) catabolic process |
| GO:1901910 | 1.53784171933e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | adenosine 5'-(hexahydrogen pentaphosphate) metabolic process |
| GO:1901909 | 1.53784171933e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | diadenosine hexaphosphate catabolic process |
| GO:1901908 | 1.53784171933e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | diadenosine hexaphosphate metabolic process |
| GO:1901907 | 1.53784171933e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | diadenosine pentaphosphate catabolic process |
| GO:1901906 | 1.53784171933e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | diadenosine pentaphosphate metabolic process |
| GO:0071543 | 1.53784171933e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | diphosphoinositol polyphosphate metabolic process |
| GO:0000298 | 1.53784171933e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | endopolyphosphatase activity |
| GO:0034432 | 1.53784171933e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | bis(5'-adenosyl)-pentaphosphatase activity |
| GO:0034431 | 1.53784171933e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | bis(5'-adenosyl)-hexaphosphatase activity |
| GO:0008486 | 1.53784171933e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | diphosphoinositol-polyphosphate diphosphatase activity |
| GO:0015961 | 3.84440695359e-06 | 0.75 | NUDT10 NUDT3 NUDT4 | diadenosine polyphosphate catabolic process |
| REAC:R-HSA-1483249 | 1.28002609524e-05 | 0.75 | NUDT10 NUDT3 NUDT4 | Inositol phosphate metabolism |
| GO:0015959 | 1.34540429244e-05 | 0.75 | NUDT10 NUDT3 NUDT4 | diadenosine polyphosphate metabolic process |
| GO:0043647 | 0.000998468305694 | 0.75 | NUDT10 NUDT3 NUDT4 | inositol phosphate metabolic process |
| GO:0019751 | 0.0152210712647 | 0.75 | NUDT10 NUDT3 NUDT4 | polyol metabolic process |
| GO:0009154 | 0.048062454325 | 0.75 | NUDT10 NUDT3 NUDT4 | purine ribonucleotide catabolic process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NUDT10 | NUDT4 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NUDT3 | NUDT10 | 0.974 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| NUDT3 | KLF16 | 0.904 | 0.076 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| NUDT10 | huMAP3_03492.1 huMAP3_06178.1 huMAP3_11322.1 |
| NUDT3 | huMAP3_00671.1 huMAP3_06178.1 huMAP3_09997.1 huMAP3_10599.1 huMAP3_11322.1 huMAP3_12785.1 |
| KLF16 | huMAP3_09685.1 huMAP3_11322.1 huMAP3_11712.1 huMAP3_11905.1 huMAP3_12785.1 |
| NUDT4 | huMAP3_03492.1 huMAP3_11322.1 |