hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11357.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| COPB2 | Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102) | 5 | UniProt NCBI |
| CYP4F3 | Cytochrome P450 4F3 (EC 1.14.14.1) (20-hydroxyeicosatetraenoic acid synthase) (20-HETE synthase) (CYPIVF3) (Cytochrome P450-LTB-omega) (Docosahexaenoic acid omega-hydroxylase CYP4F3) (EC 1.14.14.79) (Leukotriene-B(4) 20-monooxygenase 2) (Leukotriene-B(4) omega-hydroxylase 2) (EC 1.14.14.94) | 5 | UniProt NCBI |
| COPG2 | Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP) | 5 | UniProt NCBI |
| COPG1 | Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP) | 5 | UniProt NCBI |
| ARCN1 | Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP) | 5 | UniProt NCBI |
| CD74 | HLA class II histocompatibility antigen gamma chain (HLA-DR antigens-associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide (CLIP)] | 5 | UniProt NCBI |
| COPZ2 | Coatomer subunit zeta-2 (Zeta-2-coat protein) (Zeta-2 COP) | 4 | UniProt NCBI |
| COPZ1 | Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP) | 5 | UniProt NCBI |
| KCNJ10 | ATP-sensitive inward rectifier potassium channel 10 (ATP-dependent inwardly rectifying potassium channel Kir4.1) (Inward rectifier K(+) channel Kir1.2) (Potassium channel, inwardly rectifying subfamily J member 10) | 5 | UniProt NCBI |
| COPA | Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin] | 5 | UniProt NCBI |
| COPB1 | Coatomer subunit beta (Beta-coat protein) (Beta-COP) | 5 | UniProt NCBI |
| KCNJ12 | ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12) | 5 | UniProt NCBI |
| COPE | Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030126 | 3.05349669742e-22 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | COPI vesicle coat |
| GO:0030663 | 1.03716537278e-20 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | COPI-coated vesicle membrane |
| GO:0030137 | 7.16056970181e-20 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | COPI-coated vesicle |
| GO:0030660 | 3.75470065178e-16 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | Golgi-associated vesicle membrane |
| REAC:R-HSA-6811434 | 2.20066785993e-15 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | COPI-dependent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-6807878 | 2.96426998974e-15 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | COPI-mediated anterograde transport |
| GO:0030120 | 3.80054213759e-15 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | vesicle coat |
| GO:0006891 | 1.30401399129e-14 | 0.615384615385 | COPG1 COPB1 COPB2 COPG2 COPZ1 COPA COPZ2 COPE | intra-Golgi vesicle-mediated transport |
| GO:0005798 | 2.38700927565e-14 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | Golgi-associated vesicle |
| REAC:R-HSA-8856688 | 3.73679453281e-14 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | Golgi-to-ER retrograde transport |
| GO:0030662 | 1.0834114923e-13 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | coated vesicle membrane |
| REAC:R-HSA-199977 | 1.20437428087e-13 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | ER to Golgi Anterograde Transport |
| GO:0030117 | 2.15078500211e-13 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | membrane coat |
| GO:0048475 | 2.15078500211e-13 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | coated membrane |
| REAC:R-HSA-948021 | 6.58403793926e-13 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | Transport to the Golgi and subsequent modification |
| REAC:R-HSA-6811442 | 1.89099467484e-12 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| GO:0030135 | 7.68132011504e-12 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | coated vesicle |
| GO:0030133 | 2.6568747804e-11 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | transport vesicle |
| REAC:R-HSA-446203 | 6.15745116341e-11 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | Asparagine N-linked glycosylation |
| GO:0000139 | 3.10023562103e-09 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | Golgi membrane |
| GO:0048193 | 7.35777454314e-09 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | Golgi vesicle transport |
| GO:0005789 | 1.05610335767e-08 | 0.846153846154 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 CYP4F3 COPB1 | endoplasmic reticulum membrane |
| GO:0098827 | 1.25250620163e-08 | 0.846153846154 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 CYP4F3 COPB1 | endoplasmic reticulum subcompartment |
| GO:0042175 | 1.37308167147e-08 | 0.846153846154 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 CYP4F3 COPB1 | nuclear outer membrane-endoplasmic reticulum membrane network |
| REAC:R-HSA-199991 | 3.4934800239e-08 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 5.66987906331e-08 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | Vesicle-mediated transport |
| GO:0006890 | 9.90278250428e-08 | 0.461538461538 | ARCN1 COPB2 COPG2 COPZ1 COPA COPZ2 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| GO:0006888 | 1.54015249201e-07 | 0.538461538462 | COPG1 COPB1 COPB2 COPG2 COPE COPA ARCN1 | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO:0031984 | 2.5505690792e-07 | 0.846153846154 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 CYP4F3 COPB1 | organelle subcompartment |
| GO:0030659 | 1.50469687255e-06 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | cytoplasmic vesicle membrane |
| GO:0012506 | 1.76071039887e-06 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | vesicle membrane |
| GO:0098796 | 1.15680585576e-05 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | membrane protein complex |
| GO:0005783 | 1.69838987719e-05 | 0.846153846154 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 CYP4F3 COPB1 | endoplasmic reticulum |
| REAC:R-HSA-597592 | 2.98907719811e-05 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | Post-translational protein modification |
| GO:0046907 | 5.48243159446e-05 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | intracellular transport |
| GO:0005794 | 8.32683077374e-05 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | Golgi apparatus |
| REAC:R-HSA-392499 | 0.000501379658429 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | Metabolism of proteins |
| GO:0051649 | 0.000629021087222 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | establishment of localization in cell |
| GO:0098588 | 0.000943900091301 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | bounding membrane of organelle |
| GO:0006810 | 0.00112624997623 | 0.923076923077 | COPG1 ARCN1 COPB2 COPG2 KCNJ10 KCNJ12 COPE COPA COPZ1 CD74 COPZ2 COPB1 | transport |
| GO:0016192 | 0.00200337775669 | 0.692307692308 | COPG1 ARCN1 COPB2 COPE COPA COPZ1 COPG2 COPZ2 COPB1 | vesicle-mediated transport |
| GO:0015031 | 0.00279550994299 | 0.615384615385 | COPG1 ARCN1 COPB2 COPG2 COPA COPZ1 CD74 COPZ2 | protein transport |
| GO:0051234 | 0.00329810686009 | 0.923076923077 | COPG1 ARCN1 COPB2 COPG2 KCNJ10 KCNJ12 COPE COPA COPZ1 CD74 COPZ2 COPB1 | establishment of localization |
| GO:0031410 | 0.00356320885352 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | cytoplasmic vesicle |
| GO:0097708 | 0.00362612809337 | 0.769230769231 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 COPB1 | intracellular vesicle |
| GO:0031090 | 0.00902823659397 | 0.846153846154 | COPG1 ARCN1 COPB2 COPG2 COPE COPA COPZ1 CD74 COPZ2 CYP4F3 COPB1 | organelle membrane |
| GO:0051179 | 0.0199727124555 | 0.923076923077 | COPG1 ARCN1 COPB2 COPG2 KCNJ10 KCNJ12 COPE COPA COPZ1 CD74 COPZ2 COPB1 | localization |
| GO:0045184 | 0.0224122970667 | 0.615384615385 | COPG1 ARCN1 COPB2 COPG2 COPA COPZ1 CD74 COPZ2 | establishment of protein localization |
| HPA:0180053 | 0.0346862806731 | 0.538461538462 | COPG1 COPB1 COPB2 COPG2 COPE COPA ARCN1 | epididymis; glandular cells[High] |
| GO:0071705 | 0.0387690228868 | 0.615384615385 | COPG1 ARCN1 COPB2 COPG2 COPA COPZ1 CD74 COPZ2 | nitrogen compound transport |
| REAC:R-HSA-1296059 | 0.0499595654642 | 0.153846153846 | KCNJ12 KCNJ10 | G protein gated Potassium channels |
| REAC:R-HSA-1296041 | 0.0499595654642 | 0.153846153846 | KCNJ12 KCNJ10 | Activation of G protein gated Potassium channels |
| REAC:R-HSA-997272 | 0.0499595654642 | 0.153846153846 | KCNJ12 KCNJ10 | Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| COPB2 | COPE | 1.0 | 0.964 |
| COPA | COPE | 1.0 | 0.924 |
| COPB1 | COPE | 1.0 | 0.962 |
| COPB2 | COPA | 1.0 | 0.964 |
| COPG1 | COPE | 1.0 | 0.91 |
| COPB2 | COPG1 | 1.0 | 0.962 |
| COPG1 | ARCN1 | 1.0 | 0.85 |
| ARCN1 | COPB1 | 1.0 | 0.986 |
| COPG1 | COPB1 | 1.0 | 0.99 |
| ARCN1 | COPA | 1.0 | 0.816 |
| COPB2 | ARCN1 | 1.0 | 0.972 |
| COPA | COPB1 | 1.0 | 0.986 |
| COPG2 | COPE | 1.0 | 0.428 |
| COPB2 | COPB1 | 1.0 | 0.974 |
| COPG1 | COPA | 1.0 | 0.952 |
| COPG2 | COPG1 | 0.999 | 0.476 |
| ARCN1 | COPE | 0.999 | 0.88 |
| COPG2 | COPB1 | 0.999 | 0.864 |
| COPG1 | COPZ1 | 0.999 | 0.724 |
| COPG2 | COPA | 0.999 | 0.76 |
| COPG2 | ARCN1 | 0.998 | 0.578 |
| COPG2 | COPZ1 | 0.998 | 0.464 |
| COPB2 | COPG2 | 0.998 | 0.812 |
| ARCN1 | COPZ1 | 0.997 | 0.842 |
| COPZ1 | COPA | 0.997 | 0.798 |
| COPB2 | COPZ1 | 0.996 | 0.916666666667 |
| COPZ1 | COPB1 | 0.996 | 0.912 |
| KCNJ12 | KCNJ10 | 0.996 | |
| COPZ1 | COPE | 0.996 | 0.882 |
| COPG1 | COPZ2 | 0.991 | 0.174 |
| COPG2 | KCNJ10 | 0.988 | |
| COPZ2 | COPB1 | 0.987 | 0.332 |
| COPZ2 | COPA | 0.984 | 0.332 |
| COPB2 | COPZ2 | 0.984 | 0.37 |
| COPZ2 | COPE | 0.983 | 0.264 |
| ARCN1 | COPZ2 | 0.98 | 0.316 |
| COPG1 | KCNJ10 | 0.974 | |
| CD74 | COPG1 | 0.936 | 0.172 |
| COPB1 | KCNJ10 | 0.923 | |
| CD74 | COPG2 | 0.915 | 0.086 |
| CD74 | COPA | 0.905 | 0.294 |
| CYP4F3 | CD74 | 0.902 | |
| COPA | KCNJ10 | 0.878 | |
| ARCN1 | KCNJ10 | 0.828 | |
| CD74 | ARCN1 | 0.825 | 0.176 |
| CD74 | COPB2 | 0.821 | 0.176 |
| COPB2 | KCNJ10 | 0.802 | |
| CD74 | COPE | 0.767 | 0.092 |
| COPE | KCNJ10 | 0.594 | |
| CD74 | COPB1 | 0.569 | 0.19 |
| COPZ1 | KCNJ10 | 0.555 | |
| KCNJ12 | COPG2 | 0.486 | |
| COPG2 | COPZ2 | 0.127 | 0.142 |
| KCNJ12 | COPA | 0.096 | |
| KCNJ12 | COPG1 | 0.096 | |
| KCNJ12 | COPB2 | 0.096 | |
| KCNJ12 | COPB1 | 0.078 | |
| KCNJ12 | COPE | 0.062 | |
| KCNJ12 | ARCN1 | 0.048 | |
| KCNJ12 | COPZ1 | 0.035 |
Related Complexes