List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_11361.1

Confidence: Medium   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
FBXW4	F-box/WD repeat-containing protein 4 (Dactylin) (F-box and WD-40 domain-containing protein 4)	4	UniProt   NCBI
KATNA1	Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 5.6.1.1) (p60 katanin)	5	UniProt   NCBI
RC3H2	Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)	5	UniProt   NCBI
MARCHF9	E3 ubiquitin-protein ligase MARCHF9 (EC 2.3.2.27) (Membrane-associated RING finger protein 9) (Membrane-associated RING-CH protein IX) (MARCH-IX) (RING finger protein 179) (RING-type E3 ubiquitin transferase MARCHF9)	5	UniProt   NCBI
KATNAL1	Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (EC 5.6.1.1) (p60 katanin-like 1)	5	UniProt   NCBI
PFDN5	Prefoldin subunit 5 (Myc modulator 1) (c-Myc-binding protein Mm-1)	5	UniProt   NCBI
PFDN1	Prefoldin subunit 1	4	UniProt   NCBI
VBP1	Prefoldin subunit 3 (HIBBJ46) (von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1)	5	UniProt   NCBI
MTFR1L	Mitochondrial fission regulator 1-like	4	UniProt   NCBI
WSB2	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein)	3	UniProt   NCBI
PFDN2	Prefoldin subunit 2	5	UniProt   NCBI
KRTAP13-3	Keratin-associated protein 13-3	5	UniProt   NCBI
KATNBL1	KATNB1-like protein 1 (Katanin p80 subunit B-like 1)	5	UniProt   NCBI
TIPARP	Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7) (TCDD-inducible poly [ADP-ribose] polymerase)	5	UniProt   NCBI
PRKG2	cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)	5	UniProt   NCBI
KATNB1	Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin)	5	UniProt   NCBI
PFDN4	Prefoldin subunit 4 (Protein C-1)	5	UniProt   NCBI
DCAF12	DDB1- and CUL4-associated factor 12 (Centrosome-related protein TCC52) (Testis cancer centrosome-related protein) (WD repeat-containing protein 40A)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:112	3.730278119e-13	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	Prefoldin complex
CORUM:33	3.730278119e-13	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	Prefoldin complex
WP:WP4918	1.09350942495e-12	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	Cellular proteostasis
CORUM:7366	6.49327829742e-11	0.222222222222	KATNAL1 KATNB1 KATNA1 KATNBL1	KATNA1-KATNAL1-KATNB1-KATNBL1 complex
GO:0016272	4.62554486756e-10	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	prefoldin complex
GO:1905907	3.54848272471e-08	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	negative regulation of amyloid fibril formation
REAC:R-HSA-389957	3.78236696294e-08	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	Prefoldin mediated transfer of substrate to CCT/TriC
GO:0008352	8.0516650888e-08	0.222222222222	KATNAL1 KATNB1 KATNA1 KATNBL1	katanin complex
REAC:R-HSA-389958	9.39992145746e-08	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
REAC:R-HSA-390466	1.75282039179e-07	0.333333333333	PFDN4 FBXW4 PFDN5 PFDN2 VBP1 PFDN1	Chaperonin-mediated protein folding
GO:1905906	2.29967832755e-07	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	regulation of amyloid fibril formation
REAC:R-HSA-391251	2.84371984557e-07	0.333333333333	PFDN4 FBXW4 PFDN5 PFDN2 VBP1 PFDN1	Protein folding
GO:1990000	3.77876631458e-05	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	amyloid fibril formation
GO:1902904	0.000129264304462	0.333333333333	PFDN4 PFDN1 PFDN5 KATNB1 PFDN2 VBP1	negative regulation of supramolecular fiber organization
GO:0061077	0.000440280615656	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	chaperone-mediated protein folding
GO:0097435	0.000585395835935	0.5	KATNAL1 PFDN1 PFDN4 PFDN5 KATNBL1 KATNB1 PFDN2 VBP1 KATNA1	supramolecular fiber organization
GO:0001540	0.000711556044524	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	amyloid-beta binding
GO:0051082	0.00541251129543	0.277777777778	PFDN2 PFDN5 PFDN4 PFDN1 VBP1	unfolded protein binding
GO:0031122	0.0105998783854	0.222222222222	KATNAL1 KATNB1 KATNA1 KATNBL1	cytoplasmic microtubule organization
GO:1902903	0.0283465732285	0.333333333333	PFDN4 PFDN1 PFDN5 KATNB1 PFDN2 VBP1	regulation of supramolecular fiber organization



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
PFDN2	VBP1	1.0	0.924
PFDN1	VBP1	1.0	0.932
PFDN4	VBP1	1.0	0.848
KATNA1	KATNB1	1.0	0.094
PFDN1	PFDN2	1.0	0.916
PFDN4	PFDN2	1.0	0.928
PFDN5	PFDN2	1.0	0.93
PFDN5	VBP1	1.0	0.866
PFDN1	PFDN5	1.0	0.936
PFDN4	PFDN1	1.0	0.92
PFDN4	PFDN5	0.999	0.902
PFDN4	MARCHF9	0.998
KATNA1	KATNBL1	0.998	0.146
KATNB1	PFDN4	0.998	0.15
KATNBL1	KATNAL1	0.998	0.08
PFDN4	RC3H2	0.996	0.182
MTFR1L	PFDN1	0.996	0.054
KATNB1	PFDN1	0.995	0.112
KATNB1	KATNBL1	0.994	0.082
FBXW4	PFDN2	0.99
WSB2	PFDN5	0.989
FBXW4	VBP1	0.984
WSB2	PFDN2	0.984
KATNA1	PFDN1	0.979	0.246
MARCHF9	VBP1	0.979
PFDN4	MTFR1L	0.977	0.034
MARCHF9	PFDN1	0.976
WSB2	VBP1	0.973
MTFR1L	PFDN2	0.971	0.056
KATNB1	PFDN2	0.965	0.116
FBXW4	PFDN5	0.957
PFDN1	FBXW4	0.947
WSB2	PFDN1	0.945
PFDN4	FBXW4	0.932
KATNA1	KATNAL1	0.911	0.078
RC3H2	PFDN1	0.909	0.21
DCAF12	PFDN2	0.905	0.046
TIPARP	PFDN2	0.9
RC3H2	PFDN2	0.894	0.258
PFDN4	WSB2	0.891
MARCHF9	PFDN5	0.869
DCAF12	PFDN5	0.865	0.108
PRKG2	PFDN5	0.846
PRKG2	VBP1	0.846
KATNAL1	PFDN1	0.845	0.074
RC3H2	MTFR1L	0.834	0.08
DCAF12	VBP1	0.833	0.09
VBP1	KRTAP13-3	0.822
DCAF12	PFDN4	0.822	0.07
PFDN1	KRTAP13-3	0.819
KATNA1	RC3H2	0.815	0.264
PFDN2	KRTAP13-3	0.807
KATNB1	KATNAL1	0.797	0.08
MTFR1L	VBP1	0.796	0.032
MTFR1L	PFDN5	0.786	0.074
PFDN5	KRTAP13-3	0.785
KATNB1	MTFR1L	0.754	0.056
PFDN4	KRTAP13-3	0.744
KATNA1	MTFR1L	0.73	0.062
KATNA1	VBP1	0.728	0.108
KATNA1	PFDN4	0.678	0.072
RC3H2	MARCHF9	0.675
MARCHF9	PFDN2	0.661
KATNA1	PFDN5	0.618	0.132
RC3H2	PFDN5	0.533	0.414
KATNB1	RC3H2	0.529	0.164
TIPARP	FBXW4	0.502
DCAF12	PFDN1	0.497	0.088
KATNB1	VBP1	0.467	0.128
KATNB1	PFDN5	0.418	0.096
RC3H2	WSB2	0.378
MTFR1L	WSB2	0.356
KATNA1	WSB2	0.334
KATNB1	DCAF12	0.321	0.076
KATNA1	DCAF12	0.299	0.07
KATNA1	PFDN2	0.277	0.252
KATNB1	WSB2	0.22
MARCHF9	MTFR1L	0.218
KATNA1	MARCHF9	0.218
PFDN4	TIPARP	0.218
TIPARP	PFDN5	0.213
KATNB1	MARCHF9	0.202
RC3H2	VBP1	0.196	0.462
KATNB1	TIPARP	0.172
DCAF12	TIPARP	0.172
DCAF12	FBXW4	0.164
TIPARP	VBP1	0.156
TIPARP	WSB2	0.146
KATNB1	FBXW4	0.143
TIPARP	PFDN1	0.141
KATNAL1	MARCHF9	0.113
KATNAL1	MTFR1L	0.095	0.08
KATNAL1	PFDN4	0.082	0.06
KATNAL1	DCAF12	0.076	0.096
PRKG2	PFDN2	0.065
RC3H2	TIPARP	0.057
RC3H2	FBXW4	0.046
KATNA1	TIPARP	0.046
WSB2	FBXW4	0.046
TIPARP	MTFR1L	0.042
DCAF12	RC3H2	0.042	0.134
DCAF12	WSB2	0.042
KATNA1	FBXW4	0.042
MTFR1L	FBXW4	0.042
DCAF12	MTFR1L	0.028	0.076
KATNAL1	RC3H2	0.026	0.116
KATNAL1	PFDN2	0.017	0.1
KATNAL1	VBP1	0.011	0.126
PRKG2	PFDN1	0.011
PRKG2	PFDN4	0.011
KATNAL1	PFDN5	0.008	0.144
KATNBL1	PFDN2	0.002	0.112





Related Complexes

Genename	Complexes
FBXW4	huMAP3_03993.1 huMAP3_04072.1 huMAP3_06614.1 huMAP3_06819.1 huMAP3_08860.1 huMAP3_09036.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_14584.1 huMAP3_14626.1
KATNA1	huMAP3_00326.1 huMAP3_04019.1 huMAP3_09573.1 huMAP3_11361.1 huMAP3_11693.1 huMAP3_13167.1 huMAP3_14626.1
RC3H2	huMAP3_01955.1 huMAP3_04521.1 huMAP3_08060.1 huMAP3_09234.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_14584.1 huMAP3_14626.1
MARCHF9	huMAP3_01955.1 huMAP3_08998.1 huMAP3_09234.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_14584.1 huMAP3_14626.1
KATNAL1	huMAP3_00793.1 huMAP3_04019.1 huMAP3_09573.1 huMAP3_11361.1 huMAP3_11693.1 huMAP3_13167.1 huMAP3_14626.1
PFDN5	huMAP3_04072.1 huMAP3_06614.1 huMAP3_06819.1 huMAP3_08860.1 huMAP3_09036.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_14584.1 huMAP3_14626.1
PFDN1	huMAP3_03956.1 huMAP3_04396.1 huMAP3_06212.1 huMAP3_07725.1 huMAP3_08998.1 huMAP3_09191.1 huMAP3_09234.1 huMAP3_10656.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_14584.1 huMAP3_14626.1
VBP1	huMAP3_06614.1 huMAP3_06819.1 huMAP3_08860.1 huMAP3_09036.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_14584.1 huMAP3_14626.1
MTFR1L	huMAP3_02935.1 huMAP3_03956.1 huMAP3_08998.1 huMAP3_09234.1 huMAP3_09720.1 huMAP3_10912.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_14584.1 huMAP3_14626.1
WSB2	huMAP3_03772.1 huMAP3_04072.1 huMAP3_04750.1 huMAP3_05894.1 huMAP3_06819.1 huMAP3_08860.1 huMAP3_08919.1 huMAP3_09036.1 huMAP3_09980.1 huMAP3_10139.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_13601.1 huMAP3_14626.1
PFDN2	huMAP3_04072.1 huMAP3_06819.1 huMAP3_09036.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_14584.1 huMAP3_14598.1 huMAP3_14626.1
KRTAP13-3	huMAP3_11361.1 huMAP3_14584.1 huMAP3_14598.1 huMAP3_14626.1
KATNBL1	huMAP3_00793.1 huMAP3_04019.1 huMAP3_09573.1 huMAP3_11361.1 huMAP3_11693.1 huMAP3_13167.1 huMAP3_14626.1
TIPARP	huMAP3_02690.1 huMAP3_10579.1 huMAP3_10797.1 huMAP3_11361.1 huMAP3_12219.1 huMAP3_14598.1 huMAP3_14626.1 huMAP3_14741.1 huMAP3_15005.1
PRKG2	huMAP3_00184.1 huMAP3_00471.1 huMAP3_04280.1 huMAP3_07508.1 huMAP3_08140.1 huMAP3_08840.1 huMAP3_09214.1 huMAP3_09609.1 huMAP3_10165.1 huMAP3_10266.1 huMAP3_11361.1 huMAP3_14584.1 huMAP3_14626.1
KATNB1	huMAP3_00326.1 huMAP3_04019.1 huMAP3_09234.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_11693.1 huMAP3_13167.1 huMAP3_14626.1
PFDN4	huMAP3_01955.1 huMAP3_08060.1 huMAP3_09234.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_14584.1 huMAP3_14626.1
DCAF12	huMAP3_01951.1 huMAP3_06559.1 huMAP3_07938.1 huMAP3_09191.1 huMAP3_10656.1 huMAP3_11361.1 huMAP3_14584.1 huMAP3_14626.1