hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11375.1
Complex Portal: CPX-19023
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OTC | Ornithine transcarbamylase, mitochondrial (OTCase) (EC 2.1.3.3) (Ornithine carbamoyltransferase, mitochondrial) | 5 | UniProt NCBI |
| POLG | DNA polymerase subunit gamma-1 (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (5'-deoxyribose-phosphate lyase) (EC 4.2.99.-) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0004353 | 2.05051410255e-05 | 1.0 | OTC POLG | Abnormal circulating pyrimidine concentration |
| HP:0010932 | 0.00294248773717 | 1.0 | OTC POLG | Abnormal circulating nucleobase concentration |
| HP:0001259 | 0.0139947587499 | 1.0 | OTC POLG | Coma |
| HP:0031980 | 0.020488053408 | 1.0 | OTC POLG | Abnormal urine carboxylic acid level |
| HP:0001399 | 0.0323058496858 | 1.0 | OTC POLG | Hepatic failure |
| HP:0003112 | 0.0371758206793 | 1.0 | OTC POLG | Abnormal circulating amino acid concentration |
| HP:0004364 | 0.042927512737 | 1.0 | OTC POLG | Abnormal circulating nitrogen compound concentration |
| KEGG:00220 | 0.0451122773679 | 0.5 | OTC | Arginine biosynthesis |
| HP:0006964 | 0.0499436884913 | 0.5 | POLG | Cerebral cortical neurodegeneration |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| POLG | OTC | 0.848 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| OTC | huMAP3_11375.1 huMAP3_13468.1 |
| POLG | huMAP3_01279.1 huMAP3_03811.1 huMAP3_11375.1 huMAP3_13468.1 |