hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_11383.1

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
YIPF3	Protein YIPF3 (Killer lineage protein 1) (Natural killer cell-specific antigen KLIP1) (YIP1 family member 3) [Cleaved into: Protein YIPF3, 36 kDa form III]	5	UniProt NCBI
SLC49A4	Solute carrier family 49 member 4 (Disrupted in renal cancer protein 2) (Disrupted in renal carcinoma protein 2)	5	UniProt NCBI
SLC43A1	Large neutral amino acids transporter small subunit 3 (L-type amino acid transporter 3) (Prostate cancer overexpressed gene 1 protein) (Solute carrier family 43 member 1)	5	UniProt NCBI
SLC16A7	Monocarboxylate transporter 2 (MCT 2) (Solute carrier family 16 member 7)	5	UniProt NCBI
NIPA2	Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2)	4	UniProt NCBI
EIF2D	Eukaryotic translation initiation factor 2D (eIF2d) (Hepatocellular carcinoma-associated antigen 56) (Ligatin)	5	UniProt NCBI
SLC22A5	Organic cation/carnitine transporter 2 (High-affinity sodium-dependent carnitine cotransporter) (Solute carrier family 22 member 5)	5	UniProt NCBI
SLC6A8	Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8)	5	UniProt NCBI
SLC43A2	Large neutral amino acids transporter small subunit 4 (L-type amino acid transporter 4) (Solute carrier family 43 member 2)	5	UniProt NCBI
PIGW	Phosphatidylinositol-glycan biosynthesis class W protein (PIG-W) (EC 2.3.-.-)	5	UniProt NCBI
SLC22A4	Solute carrier family 22 member 4 (Ergothioneine transporter) (ET transporter) (ETTh) (Organic cation/carnitine transporter 1) (OCTN1)	5	UniProt NCBI
SLC25A42	Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-425407	2.98812189291e-05	0.416666666667	SLC16A7 SLC43A2 SLC22A4 SLC43A1 SLC22A5	SLC-mediated transmembrane transport
GO:0008514	6.35601043801e-05	0.5	SLC43A1 SLC16A7 SLC43A2 SLC22A4 SLC25A42 SLC6A8	organic anion transmembrane transporter activity
GO:1905039	0.000286226865954	0.416666666667	SLC16A7 SLC43A2 SLC22A4 SLC43A1 SLC6A8	carboxylic acid transmembrane transport
GO:1903825	0.000302942254778	0.416666666667	SLC16A7 SLC43A2 SLC22A4 SLC43A1 SLC6A8	organic acid transmembrane transport
GO:0015711	0.000394540992083	0.5	SLC43A1 SLC16A7 SLC43A2 SLC22A4 SLC25A42 SLC6A8	organic anion transport
REAC:R-HSA-382551	0.000476277230773	0.5	SLC43A1 SLC16A7 SLC43A2 SLC22A4 NIPA2 SLC22A5	Transport of small molecules
GO:0046943	0.00076282923855	0.416666666667	SLC16A7 SLC43A2 SLC22A4 SLC43A1 SLC6A8	carboxylic acid transmembrane transporter activity
GO:0005342	0.000799182945333	0.416666666667	SLC16A7 SLC43A2 SLC22A4 SLC43A1 SLC6A8	organic acid transmembrane transporter activity
REAC:R-HSA-425366	0.00263073841387	0.25	SLC16A7 SLC22A4 SLC22A5	Transport of bile salts and organic acids, metal ions and amine compounds
GO:0071702	0.00326783799216	0.75	EIF2D SLC49A4 SLC25A42 SLC43A2 SLC6A8 SLC22A4 SLC22A5 SLC16A7 SLC43A1	organic substance transport
REAC:R-HSA-549127	0.00468950688317	0.166666666667	SLC22A5 SLC22A4	Organic cation transport
GO:0046942	0.00701586783564	0.416666666667	SLC16A7 SLC43A2 SLC22A4 SLC43A1 SLC6A8	carboxylic acid transport
GO:0015849	0.00722685728433	0.416666666667	SLC16A7 SLC43A2 SLC22A4 SLC43A1 SLC6A8	organic acid transport
GO:0015171	0.00806066331254	0.333333333333	SLC43A2 SLC22A4 SLC43A1 SLC6A8	amino acid transmembrane transporter activity
REAC:R-HSA-549132	0.00919893032747	0.166666666667	SLC22A5 SLC22A4	Organic cation/anion/zwitterion transport
GO:0071705	0.0159439788671	0.666666666667	SLC43A1 SLC49A4 SLC43A2 SLC22A4 SLC22A5 SLC25A42 EIF2D SLC6A8	nitrogen compound transport
GO:0022857	0.0166490316921	0.583333333333	SLC43A1 SLC16A7 SLC43A2 SLC22A4 SLC22A5 SLC25A42 SLC6A8	transmembrane transporter activity
GO:0015101	0.0203399151593	0.25	SLC22A5 SLC22A4 SLC25A42	organic cation transmembrane transporter activity
HP:0002311	0.0265013638998	0.333333333333	NIPA2 SLC25A42 SLC6A8 SLC22A5	Incoordination
GO:0072349	0.0278917334495	0.25	SLC22A5 SLC6A8 SLC22A4	modified amino acid transmembrane transporter activity
GO:0060358	0.0309012475255	0.166666666667	SLC43A1 SLC43A2	negative regulation of leucine import
GO:1905532	0.0309012475255	0.166666666667	SLC43A1 SLC43A2	regulation of leucine import across plasma membrane
GO:0060357	0.0309012475255	0.166666666667	SLC43A1 SLC43A2	regulation of leucine import
GO:1905533	0.0309012475255	0.166666666667	SLC43A1 SLC43A2	negative regulation of leucine import across plasma membrane
GO:0055085	0.0344231128443	0.583333333333	SLC43A1 SLC16A7 SLC43A2 SLC22A4 SLC22A5 SLC25A42 SLC6A8	transmembrane transport
GO:0005215	0.0359686680099	0.583333333333	SLC43A1 SLC16A7 SLC43A2 SLC22A4 SLC22A5 SLC25A42 SLC6A8	transporter activity
GO:0072337	0.0371057242165	0.25	SLC22A5 SLC6A8 SLC22A4	modified amino acid transport
REAC:R-HSA-352230	0.0384420778088	0.166666666667	SLC43A1 SLC43A2	Amino acid transport across the plasma membrane

Edges

Protein 1	Protein 2	Score	ProteomeHD
PIGW	YIPF3	0.99
SLC49A4	SLC22A4	0.987
YIPF3	SLC43A1	0.981	0.094
NIPA2	SLC22A4	0.98
YIPF3	SLC22A5	0.978
YIPF3	SLC6A8	0.977	0.076
YIPF3	SLC43A2	0.965	0.042
SLC22A4	SLC43A1	0.951
SLC22A4	SLC22A5	0.948
SLC25A42	SLC22A4	0.938
NIPA2	YIPF3	0.927	0.132
SLC22A4	EIF2D	0.915
NIPA2	SLC16A7	0.892	0.072
SLC22A4	SLC6A8	0.879
SLC22A4	PIGW	0.818
NIPA2	SLC6A8	0.804	0.058
SLC16A7	YIPF3	0.587	0.032
SLC43A1	SLC43A2	0.502	0.114
NIPA2	SLC43A2	0.502	0.1
SLC49A4	EIF2D	0.415	0.026
SLC16A7	SLC6A8	0.343	0.076
SLC22A5	SLC43A2	0.333
SLC22A4	YIPF3	0.323
NIPA2	EIF2D	0.278	0.068
SLC25A42	EIF2D	0.274	0.04
SLC43A1	EIF2D	0.274	0.082
NIPA2	SLC43A1	0.265	0.116
NIPA2	SLC22A5	0.262
SLC43A1	SLC22A5	0.262
SLC49A4	NIPA2	0.25	0.144
NIPA2	PIGW	0.237
PIGW	SLC43A1	0.237
PIGW	SLC22A5	0.202
PIGW	SLC43A2	0.172
SLC6A8	SLC43A2	0.172	0.052
SLC43A1	SLC6A8	0.165	0.09
SLC49A4	SLC43A1	0.113	0.1
SLC22A5	EIF2D	0.113
SLC25A42	NIPA2	0.095	0.044
SLC22A5	SLC6A8	0.091
SLC25A42	SLC6A8	0.087	0.044
SLC25A42	PIGW	0.087
SLC49A4	YIPF3	0.082	0.146
SLC25A42	SLC49A4	0.079	0.062
SLC25A42	SLC43A1	0.078	0.03
PIGW	EIF2D	0.078
SLC49A4	SLC22A5	0.078
SLC6A8	EIF2D	0.076	0.042
SLC49A4	PIGW	0.076
SLC25A42	SLC22A5	0.076
SLC49A4	SLC6A8	0.076	0.196
YIPF3	EIF2D	0.068	0.03
SLC25A42	YIPF3	0.053	0.108
PIGW	SLC6A8	0.043

Related Complexes

Genename	Complexes
YIPF3	huMAP3_03783.1 huMAP3_06247.1 huMAP3_06493.1 huMAP3_07410.1 huMAP3_08419.1 huMAP3_08819.1 huMAP3_09884.1 huMAP3_10274.1 huMAP3_11383.1
SLC49A4	huMAP3_00508.1 huMAP3_06893.1 huMAP3_11383.1 huMAP3_11807.1 huMAP3_12493.1 huMAP3_12885.1 huMAP3_14859.1
SLC43A1	huMAP3_03783.1 huMAP3_07044.1 huMAP3_09370.1 huMAP3_10274.1 huMAP3_11383.1 huMAP3_11397.1 huMAP3_11593.1 huMAP3_12160.1 huMAP3_14441.1 huMAP3_15029.1
SLC16A7	huMAP3_01472.1 huMAP3_03300.1 huMAP3_05957.1 huMAP3_07901.1 huMAP3_11218.1 huMAP3_11345.1 huMAP3_11383.1 huMAP3_12623.1
NIPA2	huMAP3_00508.1 huMAP3_01472.1 huMAP3_05394.1 huMAP3_05972.1 huMAP3_07901.1 huMAP3_11218.1 huMAP3_11383.1 huMAP3_11743.1
EIF2D	huMAP3_11383.1 huMAP3_11807.1 huMAP3_12493.1 huMAP3_12778.1 huMAP3_12885.1 huMAP3_14859.1
SLC22A5	huMAP3_03783.1 huMAP3_06951.1 huMAP3_08419.1 huMAP3_10274.1 huMAP3_11383.1 huMAP3_11807.1 huMAP3_14859.1
SLC6A8	huMAP3_03783.1 huMAP3_04130.1 huMAP3_05991.1 huMAP3_06169.1 huMAP3_09296.1 huMAP3_09534.1 huMAP3_10274.1 huMAP3_10992.1 huMAP3_11383.1
SLC43A2	huMAP3_03783.1 huMAP3_06493.1 huMAP3_08419.1 huMAP3_10274.1 huMAP3_11383.1
PIGW	huMAP3_01752.1 huMAP3_03783.1 huMAP3_04203.1 huMAP3_06205.1 huMAP3_06493.1 huMAP3_07406.1 huMAP3_08014.1 huMAP3_08118.1 huMAP3_08419.1 huMAP3_10274.1 huMAP3_11383.1 huMAP3_11807.1
SLC22A4	huMAP3_00508.1 huMAP3_06893.1 huMAP3_11383.1 huMAP3_11807.1 huMAP3_12493.1 huMAP3_12885.1 huMAP3_14859.1
SLC25A42	huMAP3_00266.1 huMAP3_02051.1 huMAP3_09758.1 huMAP3_09993.1 huMAP3_10109.1 huMAP3_10809.1 huMAP3_11383.1 huMAP3_11449.1 huMAP3_11601.1 huMAP3_12493.1 huMAP3_12656.1 huMAP3_12720.1 huMAP3_12885.1 huMAP3_13183.1 huMAP3_13997.1 huMAP3_14433.1 huMAP3_14524.1 huMAP3_15336.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_11383.1