hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11386.1
Complex Portal: CPX-17054
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SSX4 | Protein SSX4 (Cancer/testis antigen 5.4) (CT5.4) | 3 | UniProt NCBI |
| RGP1 | RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog) | 5 | UniProt NCBI |
| SYNGR1 | Synaptogyrin-1 | 5 | UniProt NCBI |
| RIC1 | Guanine nucleotide exchange factor subunit RIC1 (Connexin-43-interacting protein of 150 kDa) (Protein RIC1 homolog) (RAB6A-GEF complex partner protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0034066 | 0.00140460216025 | 0.666666666667 | RGP1 RIC1 | Ric1-Rgp1 guanyl-nucleotide exchange factor complex |
| REAC:R-HSA-6811438 | 0.00643790104829 | 0.666666666667 | RGP1 RIC1 | Intra-Golgi traffic |
| REAC:R-HSA-6811440 | 0.00735562020533 | 0.666666666667 | RGP1 RIC1 | Retrograde transport at the Trans-Golgi-Network |
| REAC:R-HSA-8876198 | 0.0220121799777 | 0.666666666667 | RGP1 RIC1 | RAB GEFs exchange GTP for GDP on RABs |
| REAC:R-HSA-9007101 | 0.0392065258044 | 0.666666666667 | RGP1 RIC1 | Rab regulation of trafficking |
| CORUM:7296 | 0.0499402709677 | 0.333333333333 | RGP1 | PRT1-RGP1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SSX4 | SYNGR1 | 0.976 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| RGP1 | RIC1 | 0.966 | 0.17 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RIC1 | SYNGR1 | 0.948 | 0.066 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RGP1 | SYNGR1 | 0.845 | 0.05 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes