hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_11413.1

Complex Portal: CPX-17439

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
PCDHB6	Protocadherin beta-6 (PCDH-beta-6)	5	UniProt NCBI
PCDHB11	Protocadherin beta-11 (PCDH-beta-11)	5	UniProt NCBI
MYRF	Myelin regulatory factor (EC 3.4.-.-) (Myelin gene regulatory factor) [Cleaved into: Myelin regulatory factor, N-terminal; Myelin regulatory factor, C-terminal]	5	UniProt NCBI
PCDHGA6	Protocadherin gamma-A6 (PCDH-gamma-A6)	4	UniProt NCBI
PCDHB16	Protocadherin beta-16 (PCDH-beta-16) (Protocadherin-3X)	5	UniProt NCBI
PCDHB8	Protocadherin beta-8 (PCDH-beta-8) (Protocadherin-3I)	4	UniProt NCBI
PCDHB7	Protocadherin beta-7 (PCDH-beta-7)	4	UniProt NCBI
PCDHGB5	Protocadherin gamma-B5 (PCDH-gamma-B5)	4	UniProt NCBI
PCDHB12	Protocadherin beta-12 (PCDH-beta-12)	5	UniProt NCBI
PCDHB9	Protocadherin beta-9 (PCDH-beta-9) (Protocadherin-3H)	4	UniProt NCBI
PCDHB2	Protocadherin beta-2 (PCDH-beta-2)	4	UniProt NCBI
PCDHB3	Protocadherin beta-3 (PCDH-beta-3)	4	UniProt NCBI
PCDHB5	Protocadherin beta-5 (PCDH-beta-5)	4	UniProt NCBI
B3GNT4	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 (EC 2.4.1.149) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4) (BGnT-4) (Beta-1,3-Gn-T4) (Beta-1,3-N-acetylglucosaminyltransferase 4) (Beta3Gn-T4)	5	UniProt NCBI
PCDHB13	Protocadherin beta-13 (PCDH-beta-13)	4	UniProt NCBI
TMTC2	Protein O-mannosyl-transferase TMTC2 (EC 2.4.1.109) (Transmembrane O-mannosyltransferase targeting cadherins 2) (Transmembrane and tetratricopeptide repeat-containing 2)	5	UniProt NCBI
TMEM97	Sigma intracellular receptor 2 (S2R) (Sigma-2 receptor) (Sigma2 receptor) (Meningioma-associated protein 30) (MAC30) (Transmembrane protein 97)	5	UniProt NCBI
PCDHB10	Protocadherin beta-10 (PCDH-beta-10)	4	UniProt NCBI
PCDHB4	Protocadherin beta-4 (PCDH-beta-4)	4	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0016339	3.45523977674e-18	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007416	4.06420979671e-13	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	synapse assembly
GO:0098742	4.49496712107e-12	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	cell-cell adhesion via plasma-membrane adhesion molecules
GO:0007155	1.26014536743e-10	0.789473684211	PCDHB16 PCDHGA6 PCDHB5 PCDHB2 PCDHB8 PCDHB4 PCDHB6 PCDHB13 PCDHB11 PCDHB12 PCDHB3 PCDHB10 PCDHGB5 PCDHB7 PCDHB9	cell adhesion
GO:0050808	2.09131516058e-09	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	synapse organization
GO:0034329	1.4526983036e-08	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	cell junction assembly
GO:0007268	2.2670208326e-07	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	chemical synaptic transmission
GO:0098916	2.2670208326e-07	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	anterograde trans-synaptic signaling
GO:0099537	2.53529758695e-07	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	trans-synaptic signaling
GO:0099536	4.46828586633e-07	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	synaptic signaling
GO:0034330	1.20796835347e-06	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	cell junction organization
GO:0098609	1.88507478201e-05	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	cell-cell adhesion
TF:M10069_1	0.000126589453222	0.631578947368	PCDHB16 PCDHB9 PCDHB5 TMEM97 PCDHB8 PCDHB11 PCDHB12 PCDHB3 PCDHB10 PCDHGB5 PCDHB13 PCDHB2	Factor: Sox-4; motif: NYCTTTGTYYYN; match class: 1
GO:0007399	0.000384650526889	0.631578947368	PCDHB16 PCDHB9 PCDHB5 PCDHB2 PCDHB4 PCDHB6 PCDHB11 PCDHB12 PCDHB10 PCDHB3 PCDHB13 MYRF	nervous system development
TF:M01284_1	0.000803117287552	0.526315789474	PCDHB16 PCDHB9 TMEM97 PCDHB8 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	Factor: Sox-9; motif: RNACAAAGGVN; match class: 1
TF:M07230_1	0.00152820116452	0.368421052632	PCDHB16 PCDHGA6 PCDHB8 PCDHB11 PCDHB12 PCDHB13 PCDHB5	Factor: TAL1::GATA1; motif: NTTATCWNNNNNNNNCAG; match class: 1
TF:M10067_1	0.00194313210129	0.526315789474	PCDHB16 PCDHB9 PCDHB8 PCDHB11 PCDHB2 PCDHB3 PCDHB10 PCDHGB5 PCDHB13 PCDHB5	Factor: Sox-2; motif: NNCCTTTGTNYYN; match class: 1
GO:0007267	0.00303732993591	0.526315789474	PCDHB16 PCDHB9 PCDHB4 PCDHB6 PCDHB11 PCDHB2 PCDHB10 PCDHB3 PCDHB13 PCDHB5	cell-cell signaling
TF:M03886	0.0456203658809	0.421052631579	PCDHB16 PCDHB10 PCDHB8 PCDHB11 PCDHB2 PCDHB3 PCDHB13 PCDHB12	Factor: Sox-2; motif: NNCCWTTGTTNTKN

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
PCDHB3	PCDHB7	1.0		mutually_exclusive (Q9NRJ7) structurally_consistent (dimer)
PCDHB8	PCDHB3	1.0		structurally_consistent (dimer)
PCDHB3	PCDHB10	1.0		mutually_exclusive (Q9NRJ7) structurally_consistent (dimer)
PCDHB5	PCDHB3	1.0		structurally_consistent (dimer)
PCDHB4	PCDHB3	1.0		structurally_consistent (dimer)
PCDHB16	PCDHB3	0.999		structurally_consistent (dimer)
PCDHB2	PCDHB3	0.999		mutually_exclusive (Q9Y5G2) structurally_consistent (dimer)
PCDHB13	PCDHB3	0.999		structurally_consistent (dimer)
PCDHB9	PCDHB3	0.999		structurally_consistent (dimer)
B3GNT4	PCDHB3	0.998
PCDHB16	PCDHB7	0.998		mutually_exclusive (Q9Y5E6) structurally_consistent (dimer)
PCDHB3	MYRF	0.998
PCDHGB5	PCDHB3	0.996		mutually_exclusive (Q9Y5G2)
TMTC2	PCDHB3	0.996
PCDHB13	PCDHB11	0.994		structurally_consistent (dimer)
PCDHGA6	PCDHB3	0.994
PCDHB6	PCDHB12	0.993		structurally_consistent (dimer)
PCDHB6	PCDHB4	0.992		structurally_consistent (dimer)
PCDHB11	PCDHB12	0.992		structurally_consistent (dimer)
PCDHB3	TMEM97	0.992
PCDHB6	PCDHB16	0.989		structurally_consistent (dimer)
PCDHB7	PCDHB12	0.988		structurally_consistent (dimer)
TMTC2	PCDHB7	0.98
PCDHB5	PCDHB11	0.959		structurally_consistent (dimer)
PCDHB4	PCDHB10	0.949		mutually_exclusive (Q9Y5E6)
PCDHB8	PCDHB10	0.949		mutually_exclusive (Q9Y5E6)
PCDHB5	PCDHB10	0.949		mutually_exclusive (Q9Y5E6)
PCDHB2	PCDHB10	0.949		mutually_exclusive (Q9Y5E6)
PCDHB9	PCDHB10	0.949		mutually_exclusive (Q9Y5E6)
TMTC2	PCDHB11	0.949
PCDHB9	PCDHB8	0.946		mutually_exclusive (Q9Y5E6)
PCDHB2	PCDHB9	0.946		mutually_exclusive (Q9Y5E6)
PCDHB4	PCDHB5	0.946		mutually_exclusive (Q9Y5E6)
PCDHB2	PCDHB8	0.946		mutually_exclusive (Q9Y5E6)
PCDHB4	PCDHB8	0.946		mutually_exclusive (Q9Y5E6)
PCDHB5	PCDHB8	0.946	0.138	mutually_exclusive (Q9Y5E6)
PCDHB5	PCDHB9	0.946		mutually_exclusive (Q9Y5E6)
PCDHB4	PCDHB9	0.946		mutually_exclusive (Q9Y5E6)
PCDHB16	PCDHB9	0.946		mutually_exclusive (Q9Y5E6)
PCDHB13	PCDHB8	0.946		mutually_exclusive (Q9Y5E6)
PCDHB16	PCDHB8	0.946		mutually_exclusive (Q9Y5E6)
PCDHB13	PCDHB9	0.946		mutually_exclusive (Q9Y5E6)
PCDHB13	PCDHB7	0.946		mutually_exclusive (Q9Y5E6)
PCDHB13	PCDHB10	0.946		mutually_exclusive (Q9Y5E6)
PCDHB9	PCDHB7	0.946		mutually_exclusive (Q9Y5E6)
PCDHB8	PCDHB7	0.946		mutually_exclusive (Q9Y5E6)
PCDHB4	PCDHB13	0.946		mutually_exclusive (Q9Y5E6)
PCDHB4	PCDHB7	0.946		mutually_exclusive (Q9Y5E6)
PCDHB16	PCDHB10	0.944		mutually_exclusive (Q9Y5E6) structurally_consistent (dimer)
PCDHB2	PCDHB4	0.933		mutually_exclusive (Q9Y5E6)
PCDHB4	PCDHB16	0.933
PCDHB13	PCDHB5	0.931
PCDHB5	PCDHB7	0.931		mutually_exclusive (Q9Y5E6)
PCDHB16	PCDHB13	0.923		mutually_exclusive (Q9Y5E6)
PCDHB2	PCDHB7	0.923		mutually_exclusive (Q9Y5E6)
PCDHB2	PCDHB13	0.923		mutually_exclusive (Q9Y5E6)
PCDHB10	PCDHB7	0.916
PCDHB4	PCDHGB5	0.904
B3GNT4	PCDHB4	0.904
PCDHB4	MYRF	0.904
TMTC2	PCDHB8	0.904	0.068
TMTC2	PCDHB9	0.904
PCDHB4	PCDHGA6	0.904
B3GNT4	PCDHB8	0.902
PCDHGA6	PCDHB9	0.902
PCDHB9	MYRF	0.902
PCDHGB5	PCDHB9	0.902
PCDHGA6	PCDHB8	0.902
B3GNT4	PCDHB10	0.902
PCDHGB5	PCDHB8	0.902
B3GNT4	PCDHB9	0.902
PCDHB8	MYRF	0.902
PCDHB10	TMEM97	0.899
PCDHB10	MYRF	0.893
PCDHB8	TMEM97	0.892	0.064
PCDHB9	TMEM97	0.892
TMTC2	PCDHB10	0.883
PCDHGB5	PCDHB16	0.863		mutually_exclusive (Q9Y5G3)
PCDHB2	PCDHB5	0.827		mutually_exclusive (Q9Y5E6)
PCDHB16	PCDHB5	0.826		mutually_exclusive (Q9Y5E6)
PCDHB2	PCDHB16	0.82
PCDHB2	PCDHGB5	0.817
PCDHGB5	PCDHB10	0.795
PCDHGA6	PCDHB10	0.795
TMTC2	PCDHB12	0.782
PCDHB2	TMTC2	0.768
PCDHB4	TMTC2	0.768
B3GNT4	PCDHB5	0.768
PCDHB5	PCDHGA6	0.768
PCDHB5	MYRF	0.768
PCDHB4	TMEM97	0.73
PCDHB2	MYRF	0.73
PCDHGB5	PCDHB5	0.73
PCDHB2	B3GNT4	0.73
TMTC2	PCDHB5	0.715	0.08
B3GNT4	PCDHB13	0.696
B3GNT4	PCDHB7	0.696
MYRF	PCDHB7	0.688
PCDHB13	MYRF	0.688
PCDHB13	PCDHGA6	0.676
PCDHGA6	PCDHB7	0.676
PCDHB2	TMEM97	0.675
PCDHB5	TMEM97	0.675	0.058
PCDHB13	TMEM97	0.675
B3GNT4	TMEM97	0.675
PCDHB16	TMEM97	0.675
TMEM97	MYRF	0.675
TMEM97	PCDHB7	0.675
PCDHGA6	TMEM97	0.675
PCDHGB5	TMEM97	0.675
TMTC2	PCDHB13	0.668
TMTC2	TMEM97	0.652	0.028
PCDHB16	TMTC2	0.651
PCDHGB5	TMTC2	0.651
PCDHB2	PCDHGA6	0.65		mutually_exclusive (Q9Y5G2)
PCDHB16	PCDHGA6	0.65
PCDHB13	PCDHB12	0.502		mutually_exclusive (Q9Y5F2)
PCDHB6	PCDHB7	0.502
PCDHGB5	PCDHB13	0.478
PCDHGB5	PCDHB7	0.478
B3GNT4	PCDHB16	0.427
PCDHB16	MYRF	0.418
B3GNT4	MYRF	0.418
PCDHGB5	MYRF	0.418
B3GNT4	PCDHGA6	0.418
PCDHB4	PCDHB12	0.415		mutually_exclusive (Q9Y5E3)
B3GNT4	PCDHGB5	0.405
PCDHGB5	PCDHGA6	0.4		mutually_exclusive (Q9Y5G2)
PCDHGA6	MYRF	0.396
B3GNT4	TMTC2	0.356
TMTC2	PCDHGA6	0.334
TMTC2	MYRF	0.22
PCDHB6	PCDHB10	0.024		mutually_exclusive (Q9NRJ7)

Related Complexes

Genename	Complexes
PCDHB6	huMAP3_01482.1 huMAP3_05891.1 huMAP3_09439.1 huMAP3_10979.1 huMAP3_11044.1 huMAP3_11413.1 huMAP3_12508.1 huMAP3_13400.1 huMAP3_14592.1
PCDHB11	huMAP3_02244.1 huMAP3_03025.1 huMAP3_05501.1 huMAP3_10554.1 huMAP3_10979.1 huMAP3_11413.1 huMAP3_11574.1 huMAP3_12508.1
MYRF	huMAP3_04901.1 huMAP3_10750.1 huMAP3_11413.1 huMAP3_11633.1 huMAP3_11729.1 huMAP3_12046.1 huMAP3_12057.1 huMAP3_12508.1 huMAP3_12626.1 huMAP3_12904.1 huMAP3_13663.1 huMAP3_15258.1
PCDHGA6	huMAP3_04006.1 huMAP3_07326.1 huMAP3_08397.1 huMAP3_08534.1 huMAP3_08651.1 huMAP3_09203.1 huMAP3_10439.1 huMAP3_11413.1 huMAP3_12057.1 huMAP3_12508.1 huMAP3_12904.1 huMAP3_13663.1 huMAP3_15258.1
PCDHB16	huMAP3_01760.1 huMAP3_10552.1 huMAP3_10979.1 huMAP3_11044.1 huMAP3_11413.1 huMAP3_12057.1 huMAP3_12210.1 huMAP3_12508.1 huMAP3_15258.1
PCDHB8	huMAP3_04259.1 huMAP3_04568.1 huMAP3_06237.1 huMAP3_07685.1 huMAP3_10979.1 huMAP3_11044.1 huMAP3_11413.1 huMAP3_12046.1 huMAP3_12057.1 huMAP3_12508.1 huMAP3_12626.1 huMAP3_12904.1 huMAP3_13663.1 huMAP3_15258.1
PCDHB7	huMAP3_05075.1 huMAP3_05078.1 huMAP3_06139.1 huMAP3_07669.1 huMAP3_10552.1 huMAP3_10979.1 huMAP3_11413.1 huMAP3_12508.1 huMAP3_13946.1 huMAP3_15258.1
PCDHGB5	huMAP3_01547.1 huMAP3_07300.1 huMAP3_09456.1 huMAP3_09591.1 huMAP3_11044.1 huMAP3_11413.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12210.1 huMAP3_12508.1 huMAP3_15204.1
PCDHB12	huMAP3_05501.1 huMAP3_05891.1 huMAP3_09439.1 huMAP3_10554.1 huMAP3_10979.1 huMAP3_11413.1 huMAP3_11574.1 huMAP3_12508.1 huMAP3_13400.1 huMAP3_13946.1 huMAP3_14592.1
PCDHB9	huMAP3_04259.1 huMAP3_04568.1 huMAP3_06237.1 huMAP3_07685.1 huMAP3_10979.1 huMAP3_11044.1 huMAP3_11413.1 huMAP3_12046.1 huMAP3_12057.1 huMAP3_12508.1 huMAP3_12626.1 huMAP3_12904.1 huMAP3_13663.1 huMAP3_15258.1
PCDHB2	huMAP3_00026.1 huMAP3_01540.1 huMAP3_01547.1 huMAP3_07685.1 huMAP3_07751.1 huMAP3_08211.1 huMAP3_09183.1 huMAP3_11044.1 huMAP3_11413.1 huMAP3_12046.1 huMAP3_12057.1 huMAP3_12210.1 huMAP3_12508.1 huMAP3_12626.1 huMAP3_12904.1 huMAP3_13663.1 huMAP3_15258.1
PCDHB3	huMAP3_04259.1 huMAP3_04568.1 huMAP3_06237.1 huMAP3_07685.1 huMAP3_10979.1 huMAP3_11044.1 huMAP3_11413.1 huMAP3_12057.1 huMAP3_12508.1 huMAP3_13663.1 huMAP3_15258.1
PCDHB5	huMAP3_02244.1 huMAP3_04568.1 huMAP3_10554.1 huMAP3_10979.1 huMAP3_11044.1 huMAP3_11413.1 huMAP3_12046.1 huMAP3_12057.1 huMAP3_12508.1 huMAP3_12626.1 huMAP3_12904.1 huMAP3_13663.1 huMAP3_15258.1
B3GNT4	huMAP3_00824.1 huMAP3_02701.1 huMAP3_04203.1 huMAP3_05640.1 huMAP3_06656.1 huMAP3_06964.1 huMAP3_07685.1 huMAP3_08118.1 huMAP3_10955.1 huMAP3_11413.1 huMAP3_12046.1 huMAP3_12057.1 huMAP3_12508.1 huMAP3_12626.1 huMAP3_12904.1 huMAP3_13663.1 huMAP3_15258.1
PCDHB13	huMAP3_02244.1 huMAP3_03025.1 huMAP3_10554.1 huMAP3_10979.1 huMAP3_11413.1 huMAP3_12046.1 huMAP3_12057.1 huMAP3_12077.1 huMAP3_12508.1 huMAP3_12626.1 huMAP3_12904.1 huMAP3_13560.1 huMAP3_13663.1 huMAP3_14269.1 huMAP3_15258.1
TMTC2	huMAP3_01866.1 huMAP3_04259.1 huMAP3_05013.1 huMAP3_05926.1 huMAP3_06139.1 huMAP3_07669.1 huMAP3_07685.1 huMAP3_08247.1 huMAP3_10708.1 huMAP3_10755.1 huMAP3_10979.1 huMAP3_11413.1 huMAP3_12046.1 huMAP3_12057.1 huMAP3_12508.1 huMAP3_12904.1 huMAP3_13663.1 huMAP3_15258.1
TMEM97	huMAP3_04861.1 huMAP3_06237.1 huMAP3_11413.1 huMAP3_12046.1 huMAP3_12057.1 huMAP3_12508.1 huMAP3_12626.1 huMAP3_13663.1 huMAP3_15258.1
PCDHB10	huMAP3_04259.1 huMAP3_04568.1 huMAP3_06237.1 huMAP3_07685.1 huMAP3_10979.1 huMAP3_11044.1 huMAP3_11413.1 huMAP3_12046.1 huMAP3_12057.1 huMAP3_12508.1 huMAP3_12626.1 huMAP3_12904.1 huMAP3_13663.1 huMAP3_15258.1
PCDHB4	huMAP3_01482.1 huMAP3_06237.1 huMAP3_09439.1 huMAP3_10979.1 huMAP3_11044.1 huMAP3_11413.1 huMAP3_12046.1 huMAP3_12057.1 huMAP3_12210.1 huMAP3_12508.1 huMAP3_12626.1 huMAP3_12904.1 huMAP3_13663.1 huMAP3_15258.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_11413.1

Complex Portal: CPX-17439