hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11418.1
Complex Portal: CPX-11734
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KLF12 | Krueppel-like factor 12 (Transcriptional repressor AP-2rep) | 5 | UniProt NCBI |
| FGF13 | Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2) | 5 | UniProt NCBI |
| SCN5A | Sodium channel protein type 5 subunit alpha (Sodium channel protein cardiac muscle subunit alpha) (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (hH1) | 5 | UniProt NCBI |
| SCHIP1 | Schwannomin-interacting protein 1 (SCHIP-1) | 5 | UniProt NCBI |
| MTMR2 | Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0005949 | 0.00288300984678 | 0.4 | FGF13 SCN5A | Apneic episodes in infancy |
| REAC:R-HSA-5576892 | 0.00418294558639 | 0.4 | FGF13 SCN5A | Phase 0 - rapid depolarisation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SCHIP1 | FGF13 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MTMR2 | SCHIP1 | 0.974 | 0.106 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| KLF12 | FGF13 | 0.964 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| FGF13 | SCN5A | 0.936 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KLF12 | SCN5A | 0.25 | 0.118 | bioplex3_WMM WMM_only | |
| MTMR2 | FGF13 | 0.25 | bioplex3_WMM WMM_only |
Related Complexes