List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_11434.1

Confidence: Medium   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
CYP8B1	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (EC 1.14.14.139) (7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase) (CYPVIIIB1) (Cytochrome P450 8B1) (Sterol 12-alpha-hydroxylase)	5	UniProt   NCBI
HERC3	Probable E3 ubiquitin-protein ligase HERC3 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 3) (HECT-type E3 ubiquitin transferase HERC3)	4	UniProt   NCBI
HSD17B3	17-beta-hydroxysteroid dehydrogenase type 3 (17-beta-HSD 3) (Estradiol 17-beta-dehydrogenase 2) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 12C member 2) (Testicular 17-beta-hydroxysteroid dehydrogenase) (Testosterone 17-beta-dehydrogenase 3) (EC 1.1.1.64)	5	UniProt   NCBI
TTLL2	Probable tubulin polyglutamylase TTLL2 (EC 6.-.-.-) (Testis-specific protein NYD-TSPG) (Tubulin--tyrosine ligase-like protein 2)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-211994	0.0499436884912	0.25	CYP8B1	Sterols are 12-hydroxylated by CYP8B1



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
HERC3	CYP8B1	0.926		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
HERC3	TTLL2	0.899		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
HERC3	HSD17B3	0.829		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM





Related Complexes

Genename	Complexes
CYP8B1	huMAP3_03964.1 huMAP3_08650.1 huMAP3_11434.1 huMAP3_14095.1
HERC3	huMAP3_01032.1 huMAP3_02853.1 huMAP3_09104.1 huMAP3_09769.1 huMAP3_11434.1
HSD17B3	huMAP3_11434.1
TTLL2	huMAP3_11434.1