hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11484.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TRIT1 | tRNA dimethylallyltransferase (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (hGRO1) (tRNA isopentenyltransferase 1) (IPTase) | 5 | UniProt NCBI |
| TRMT5 | tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6782315 | 0.00113803532692 | 1.0 | TRIT1 TRMT5 | tRNA modification in the nucleus and cytosol |
| HP:0008347 | 0.00507502240382 | 1.0 | TRIT1 TRMT5 | Decreased activity of mitochondrial complex IV |
| REAC:R-HSA-72306 | 0.00828920325958 | 1.0 | TRIT1 TRMT5 | tRNA processing |
| HP:0011923 | 0.0133830220427 | 1.0 | TRIT1 TRMT5 | Decreased activity of mitochondrial complex I |
| GO:0070900 | 0.016855225923 | 1.0 | TRIT1 TRMT5 | mitochondrial tRNA modification |
| GO:1900864 | 0.016855225923 | 1.0 | TRIT1 TRMT5 | mitochondrial RNA modification |
| HP:0008972 | 0.0277776310426 | 1.0 | TRIT1 TRMT5 | Decreased activity of mitochondrial respiratory chain |
| HP:0011922 | 0.0295479082178 | 1.0 | TRIT1 TRMT5 | Abnormal activity of mitochondrial respiratory chain |
| GO:0090646 | 0.0365196561665 | 1.0 | TRIT1 TRMT5 | mitochondrial tRNA processing |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TRMT5 | TRIT1 | 0.801 | 0.1 | bioplex3_WMM youn_WMM WMM_only |
Related Complexes