hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
TRIT1	tRNA dimethylallyltransferase (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (hGRO1) (tRNA isopentenyltransferase 1) (IPTase)	5	UniProt NCBI
TRMT5	tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-6782315	0.00113803532692	1.0	TRIT1 TRMT5	tRNA modification in the nucleus and cytosol
HP:0008347	0.00507502240382	1.0	TRIT1 TRMT5	Decreased activity of mitochondrial complex IV
REAC:R-HSA-72306	0.00828920325958	1.0	TRIT1 TRMT5	tRNA processing
HP:0011923	0.0133830220427	1.0	TRIT1 TRMT5	Decreased activity of mitochondrial complex I
GO:0070900	0.016855225923	1.0	TRIT1 TRMT5	mitochondrial tRNA modification
GO:1900864	0.016855225923	1.0	TRIT1 TRMT5	mitochondrial RNA modification
HP:0008972	0.0277776310426	1.0	TRIT1 TRMT5	Decreased activity of mitochondrial respiratory chain
HP:0011922	0.0295479082178	1.0	TRIT1 TRMT5	Abnormal activity of mitochondrial respiratory chain
GO:0090646	0.0365196561665	1.0	TRIT1 TRMT5	mitochondrial tRNA processing

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
TRMT5	TRIT1	0.801	0.1		bioplex3_WMM youn_WMM WMM_only

Genename	Complexes
TRIT1	huMAP3_02718.1 huMAP3_11244.1 huMAP3_11484.1 huMAP3_14743.1 huMAP3_15304.1
TRMT5	huMAP3_01128.1 huMAP3_02385.1 huMAP3_07252.1 huMAP3_07579.1 huMAP3_09052.1 huMAP3_10835.1 huMAP3_11244.1 huMAP3_11484.1 huMAP3_11920.1 huMAP3_14743.1