hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11500.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NFIB | Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein) | 5 | UniProt NCBI |
| NFIX | Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein) | 5 | UniProt NCBI |
| NFIA | Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-73980 | 8.26352391973e-07 | 1.0 | NFIX NFIB NFIA | RNA Polymerase III Transcription Termination |
| REAC:R-HSA-749476 | 4.26427696795e-06 | 1.0 | NFIX NFIB NFIA | RNA Polymerase III Abortive And Retractive Initiation |
| REAC:R-HSA-74158 | 4.26427696795e-06 | 1.0 | NFIX NFIB NFIA | RNA Polymerase III Transcription |
| HP:0012741 | 0.000986522412937 | 0.666666666667 | NFIX NFIB | Unilateral cryptorchidism |
| HPA:0461443 | 0.00122038823392 | 1.0 | NFIX NFIB NFIA | skin 1; fibrohistiocytic cells[High] |
| HP:0100729 | 0.00230958793402 | 1.0 | NFIX NFIB NFIA | Large face |
| HPA:0400653 | 0.00341538204963 | 0.666666666667 | NFIB NFIA | rectum; fibroblasts[High] |
| HPA:0461392 | 0.00491069279856 | 1.0 | NFIX NFIB NFIA | skin 1; cells in basal layer[>=Medium] |
| HP:0001274 | 0.00500021216384 | 1.0 | NFIX NFIB NFIA | Agenesis of corpus callosum |
| HPA:0471412 | 0.00581164540589 | 1.0 | NFIX NFIB NFIA | skin 2; cells in spinous layer[>=Medium] |
| HPA:0461442 | 0.0062577927992 | 1.0 | NFIX NFIB NFIA | skin 1; fibrohistiocytic cells[>=Medium] |
| HPA:0470181 | 0.00660698711107 | 1.0 | NFIX NFIB NFIA | skin 2; cells in granular layer[>=Low] |
| HP:0000256 | 0.00731040972407 | 1.0 | NFIX NFIB NFIA | Macrocephaly |
| HPA:0400203 | 0.00754626791577 | 0.666666666667 | NFIB NFIA | rectum; endothelial cells[High] |
| HP:0040194 | 0.00785695607115 | 1.0 | NFIX NFIB NFIA | Increased head circumference |
| HPA:0471392 | 0.00799822858561 | 1.0 | NFIX NFIB NFIA | skin 2; cells in basal layer[>=Medium] |
| HPA:0461411 | 0.0084089015935 | 1.0 | NFIX NFIB NFIA | skin 1; cells in spinous layer[>=Low] |
| HPA:0400652 | 0.00992024532416 | 0.666666666667 | NFIB NFIA | rectum; fibroblasts[>=Medium] |
| HP:0000463 | 0.00994692183455 | 1.0 | NFIX NFIB NFIA | Anteverted nares |
| HPA:0471442 | 0.0105118333285 | 1.0 | NFIX NFIB NFIA | skin 2; fibrohistiocytic cells[>=Medium] |
| HP:0005288 | 0.0110790903562 | 1.0 | NFIX NFIB NFIA | Abnormal nostril morphology |
| HPA:0400651 | 0.0121808707248 | 0.666666666667 | NFIB NFIA | rectum; fibroblasts[>=Low] |
| HPA:0471411 | 0.012211103258 | 1.0 | NFIX NFIB NFIA | skin 2; cells in spinous layer[>=Low] |
| HPA:0461441 | 0.0127085332088 | 1.0 | NFIX NFIB NFIA | skin 1; fibrohistiocytic cells[>=Low] |
| HPA:0461391 | 0.0128927121824 | 1.0 | NFIX NFIB NFIA | skin 1; cells in basal layer[>=Low] |
| HP:0000752 | 0.0146990195962 | 1.0 | NFIX NFIB NFIA | Hyperactivity |
| HPA:0471391 | 0.0165736132678 | 1.0 | NFIX NFIB NFIA | skin 2; cells in basal layer[>=Low] |
| HP:0000429 | 0.0178248545893 | 1.0 | NFIX NFIB NFIA | Abnormal morphology of the nasal alae |
| HPA:0471441 | 0.0193402202577 | 1.0 | NFIX NFIB NFIA | skin 2; fibrohistiocytic cells[>=Low] |
| HP:0000734 | 0.0221003701364 | 1.0 | NFIX NFIB NFIA | Disinhibition |
| HPA:0400202 | 0.0244321680476 | 0.666666666667 | NFIB NFIA | rectum; endothelial cells[>=Medium] |
| HP:0000965 | 0.0270637362845 | 0.666666666667 | NFIX NFIA | Cutis marmorata |
| HPA:0151342 | 0.0298945095171 | 0.666666666667 | NFIB NFIA | duodenum; glands of Brunner[>=Medium] |
| HP:0000396 | 0.0313463863633 | 0.666666666667 | NFIX NFIA | Overfolded helix |
| HPA:0461393 | 0.0323023843332 | 0.666666666667 | NFIX NFIB | skin 1; cells in basal layer[High] |
| HPA:0030432 | 0.0366451526634 | 0.666666666667 | NFIB NFIA | appendix; germinal center cells[>=Medium] |
| HP:0200006 | 0.0371287212398 | 1.0 | NFIX NFIB NFIA | Slanting of the palpebral fissure |
| HP:0008544 | 0.0388502441646 | 0.666666666667 | NFIX NFIA | Abnormally folded helix |
| HP:0002119 | 0.043601990352 | 1.0 | NFIX NFIB NFIA | Ventriculomegaly |
| HP:0007370 | 0.0449808704429 | 1.0 | NFIX NFIB NFIA | Aplasia/Hypoplasia of the corpus callosum |
| HP:0003745 | 0.045003983416 | 0.666666666667 | NFIX NFIA | Sporadic |
| HPA:0400201 | 0.0461437218829 | 0.666666666667 | NFIB NFIA | rectum; endothelial cells[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NFIB | NFIX | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| NFIB | NFIA | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM | |
| NFIX | NFIA | 0.557 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| NFIB | huMAP3_01226.1 huMAP3_08589.1 huMAP3_11500.1 huMAP3_13816.1 |
| NFIX | huMAP3_01226.1 huMAP3_11500.1 huMAP3_13816.1 |
| NFIA | huMAP3_01226.1 huMAP3_11500.1 huMAP3_13816.1 |