hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11507.1
Complex Portal: CPX-14456
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TM2D1 | TM2 domain-containing protein 1 (Amyloid-beta-binding protein) (hBBP) | 5 | UniProt NCBI |
| TMX2 | Thioredoxin-related transmembrane protein 2 (Cell proliferation-inducing gene 26 protein) (Thioredoxin domain-containing protein 14) | 5 | UniProt NCBI |
| SGK3 | Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) | 5 | UniProt NCBI |
| CYP19A1 | Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase) | 5 | UniProt NCBI |
| FAAH | Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Fatty acid ester hydrolase) (EC 3.1.1.-) (Oleamide hydrolase 1) | 5 | UniProt NCBI |
| CD200 | OX-2 membrane glycoprotein (CD antigen CD200) | 5 | UniProt NCBI |
| ADCY3 | Adenylate cyclase type 3 (EC 4.6.1.1) (ATP pyrophosphate-lyase 3) (Adenylate cyclase type III) (AC-III) (Adenylate cyclase, olfactive type) (Adenylyl cyclase 3) (AC3) | 5 | UniProt NCBI |
| PCNX3 | Pecanex-like protein 3 (Pecanex homolog protein 3) | 4 | UniProt NCBI |
| SLC4A8 | Electroneutral sodium bicarbonate exchanger 1 (Electroneutral Na(+)-driven Cl-HCO3 exchanger) (Solute carrier family 4 member 8) (k-NBC3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CYP19A1 | CD200 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CYP19A1 | FAAH | 0.984 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CYP19A1 | TMX2 | 0.982 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CYP19A1 | SGK3 | 0.976 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CYP19A1 | PCNX3 | 0.963 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SLC4A8 | ADCY3 | 0.962 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CYP19A1 | ADCY3 | 0.959 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TMX2 | PCNX3 | 0.912 | 0.114 | bioplex_WMM bioplex3_WMM WMM_only | |
| TMX2 | SLC4A8 | 0.898 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SLC4A8 | PCNX3 | 0.885 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TM2D1 | PCNX3 | 0.879 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ADCY3 | PCNX3 | 0.826 | 0.132 | bioplex_WMM bioplex3_WMM WMM_only | |
| TMX2 | ADCY3 | 0.521 | 0.116 | bioplex_WMM bioplex3_WMM WMM_only | |
| FAAH | ADCY3 | 0.482 | 0.102 | bioplex3_WMM WMM_only | |
| FAAH | TMX2 | 0.376 | 0.088 | bioplex3_WMM WMM_only | |
| FAAH | PCNX3 | 0.352 | 0.048 | bioplex3_WMM WMM_only | |
| TMX2 | SGK3 | 0.182 | 0.058 | bioplex_WMM bioplex3_WMM WMM_only | |
| SGK3 | ADCY3 | 0.181 | 0.11 | bioplex_WMM bioplex3_WMM WMM_only | |
| FAAH | SGK3 | 0.042 | 0.08 |
structurally_consistent (P11511)
|
bioplex3_WMM WMM_only |
| SGK3 | PCNX3 | 0.026 | 0.07 | bioplex3_WMM WMM_only | |
| ADCY3 | TM2D1 | 0.013 | bioplex3_WMM WMM_only |
Related Complexes