hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11524.1
Complex Portal: CPX-18727
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SYAP1 | Synapse-associated protein 1 (BSD domain-containing signal transducer and Akt interactor protein) (BSTA) | 5 | UniProt NCBI |
| CTH | Cystathionine gamma-lyase (CGL) (CSE) (EC 4.4.1.1) (Cysteine desulfhydrase) (Cysteine-protein sulfhydrase) (Gamma-cystathionase) (Homocysteine desulfhydrase) (EC 4.4.1.2) | 5 | UniProt NCBI |
| PDXP | Chronophin (EC 3.1.3.16) (EC 3.1.3.74) (Pyridoxal phosphate phosphatase) (PLP phosphatase) | 5 | UniProt NCBI |
| GSS | Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) | 5 | UniProt NCBI |
| PGP | Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP) | 5 | UniProt NCBI |
| ZDHHC16 | Palmitoyltransferase ZDHHC16 (EC 2.3.1.225) (Abl-philin 2) (Zinc finger DHHC domain-containing protein 16) (DHHC-16) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4504 | 0.000784355919022 | 0.333333333333 | CTH GSS | Cysteine and methionine catabolism |
| KEGG:00270 | 0.00746443583489 | 0.333333333333 | CTH GSS | Cysteine and methionine metabolism |
| WP:WP3940 | 0.00903081201495 | 0.333333333333 | CTH GSS | One carbon metabolism and related pathways |
| WP:WP2525 | 0.0148188030846 | 0.333333333333 | CTH GSS | Trans sulfuration one carbon metabolism and related pathways |
| WP:WP4313 | 0.0164862310333 | 0.333333333333 | CTH GSS | Ferroptosis |
| WP:WP3925 | 0.0337850948883 | 0.333333333333 | CTH GSS | Amino acid metabolism |
| KEGG:01100 | 0.0414134615413 | 0.666666666667 | PGP PDXP CTH GSS | Metabolic pathways |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PDXP | ZDHHC16 | 0.993 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PDXP | PGP | 0.933 | 0.016 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZDHHC16 | PGP | 0.922 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PDXP | CTH | 0.917 | 0.07 | bioplex_WMM bioplex3_WMM fraction | |
| PDXP | SYAP1 | 0.877 | 0.014 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZDHHC16 | GSS | 0.864 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PDXP | GSS | 0.819 | 0.036 | bioplex_WMM bioplex3_WMM WMM_only | |
| CTH | SYAP1 | 0.647 | 0.13 | bioplex_WMM bioplex3_WMM WMM_only | |
| PGP | GSS | 0.581 | 0.052 | bioplex_WMM bioplex3_WMM fraction | |
| CTH | GSS | 0.392 | 0.0885714285714 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction | |
| PGP | CTH | 0.191 | 0.146 | bioplex_WMM bioplex3_WMM fraction | |
| GSS | SYAP1 | 0.154 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only | |
| PGP | SYAP1 | 0.053 | 0.134 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes