hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11525.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCTD18 | BTB/POZ domain-containing protein KCTD18 | 3 | UniProt NCBI |
| CCDC66 | Coiled-coil domain-containing protein 66 | 5 | UniProt NCBI |
| LRP1 | Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] | 5 | UniProt NCBI |
| HOXD4 | Homeobox protein Hox-D4 (Homeobox protein HHO.C13) (Homeobox protein Hox-4B) (Homeobox protein Hox-5.1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7535 | 0.0249718442456 | 0.25 | LRP1 | CD44-LRP1 complex |
| CORUM:2709 | 0.049938562206 | 0.25 | LRP1 | MMP-9-TIMP-1-LRP complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HOXD4 | LRP1 | 0.928 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| LRP1 | KCTD18 | 0.916 | 0.082 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CCDC66 | LRP1 | 0.874 | 0.178666666667 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes