hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
ESR1	Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)	5	UniProt NCBI
PPP1R14C	Protein phosphatase 1 regulatory subunit 14C (Kinase-enhanced PP1 inhibitor) (PKC-potentiated PP1 inhibitory protein) (Serologically defined breast cancer antigen NY-BR-81)	4	UniProt NCBI
PNMT	Phenylethanolamine N-methyltransferase (PNMTase) (EC 2.1.1.28) (Noradrenaline N-methyltransferase)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP2882	0.0133543614478	1.0	ESR1 PPP1R14C	Nuclear receptors meta pathway
WP:WP5235	0.0186595012434	0.5	ESR1	Estradiol regulation in porto sinusoidal vascular disease
CORUM:1054	0.0499419797295	0.5	ESR1	ESR1-RELA-BCL3-NCOA3 complex
CORUM:2124	0.0499419797295	0.5	ESR1	IKK-alpha--ER-alpha-AIB1 complex
CORUM:2700	0.0499419797295	0.5	ESR1	ESR1-JUN complex
CORUM:5862	0.0499419797295	0.5	ESR1	CAV1-VDAC1-ESR1 complex
CORUM:6067	0.0499419797295	0.5	ESR1	ESR1-SP1 complex
CORUM:6068	0.0499419797295	0.5	ESR1	ESR1-CEBPB complex
CORUM:6069	0.0499419797295	0.5	ESR1	ESR1-GRIP1 complex
CORUM:6251	0.0499419797295	0.5	ESR1	Shc-ERalpha-IGF-1R complex
CORUM:7249	0.0499419797295	0.5	ESR1	ERS1-MDM2 complex
CORUM:7250	0.0499419797295	0.5	ESR1	ESR1-MDM4 complex
CORUM:7312	0.0499419797295	0.5	ESR1	CTNNB1-ESR1 complex
CORUM:7586	0.0499419797295	0.5	ESR1	FOXO1-ESR1 complex
HP:0031428	0.0499436884913	0.5	ESR1	Increased circulating osteocalcin level

Protein 1	Protein 2	Score	Evidence
ESR1	PPP1R14C	0.982	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
PNMT	ESR1	0.912	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
PNMT	PPP1R14C	0.421	bioplex_WMM bioplex3_WMM WMM_only