hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_11535.1

Complex Portal: CPX-24811

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
FAM193A	Protein FAM193A (Protein IT14)	3	UniProt NCBI
AIFM1	Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8)	5	UniProt NCBI
CHCHD4	Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4)	5	UniProt NCBI
HOXD1	Homeobox protein Hox-D1 (Homeobox protein Hox-GG)	4	UniProt NCBI
GFER	FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration) (hERV1) (Hepatopoietin)	5	UniProt NCBI
CHCHD5	Coiled-coil-helix-coiled-coil-helix domain-containing protein 5	3	UniProt NCBI
ZNF518B	Zinc finger protein 518B	3	UniProt NCBI
AK2	Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) [Cleaved into: Adenylate kinase 2, mitochondrial, N-terminally processed]	5	UniProt NCBI
COX17	Cytochrome c oxidase copper chaperone	5	UniProt NCBI
KPLCE	Protein KPLCE (KPRP N-terminal and LCE C-terminal-like protein) (Skin-specific protein 32)	2	UniProt NCBI
THAP4	Peroxynitrite isomerase THAP4 (EC 5.99.-.-) (Ferric Homo sapiens nitrobindin) (Hs-Nb(III)) (THAP domain-containing protein 4)	5	UniProt NCBI
ZNRF2	E3 ubiquitin-protein ligase ZNRF2 (EC 2.3.2.27) (Protein Ells2) (RING finger protein 202) (RING-type E3 ubiquitin transferase ZNRF2) (Zinc/RING finger protein 2)	5	UniProt NCBI
CCBE1	Collagen and calcium-binding EGF domain-containing protein 1 (Full of fluid protein homolog)	5	UniProt NCBI
SUOX	Sulfite oxidase, mitochondrial (EC 1.8.3.1)	5	UniProt NCBI
TXN	Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx)	5	UniProt NCBI
CAMTA1	Calmodulin-binding transcription activator 1	5	UniProt NCBI
HOXB1	Homeobox protein Hox-B1 (Homeobox protein Hox-2I)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-1268020	0.000101393516557	0.266666666667	GFER CHCHD4 COX17 CHCHD5	Mitochondrial protein import
GO:0005758	0.000131261854127	0.333333333333	AIFM1 AK2 CHCHD4 COX17 CHCHD5	mitochondrial intermembrane space
GO:0031970	0.000215823179568	0.333333333333	AIFM1 AK2 CHCHD4 COX17 CHCHD5	organelle envelope lumen
REAC:R-HSA-9609507	0.00270762753596	0.266666666667	GFER CHCHD4 COX17 CHCHD5	Protein localization

Edges

Protein 1	Protein 2	Score	ProteomeHD
TXN	CHCHD4	0.999	0.044
AIFM1	AK2	0.999	0.47
AIFM1	CHCHD4	0.998	0.476
CAMTA1	CHCHD4	0.998
AIFM1	GFER	0.995	0.214
CHCHD4	AK2	0.993	0.332
CAMTA1	AIFM1	0.992
HOXD1	HOXB1	0.989
CHCHD4	GFER	0.986	0.072
GFER	HOXB1	0.985
AIFM1	TXN	0.977	0.182
AK2	HOXB1	0.961
AIFM1	HOXB1	0.959
CCBE1	CHCHD4	0.95
CHCHD4	HOXB1	0.95
CCBE1	AIFM1	0.946
CHCHD4	CHCHD5	0.919	0.112
CHCHD4	FAM193A	0.919	0.074
THAP4	CHCHD4	0.917	0.062
CHCHD4	ZNRF2	0.917	0.016
CHCHD4	ZNF518B	0.916
CAMTA1	ZNF518B	0.904
THAP4	ZNF518B	0.904
SUOX	CHCHD4	0.875	0.086
CCBE1	AK2	0.87
THAP4	KPLCE	0.836
GFER	CHCHD5	0.829	0.078
SUOX	CHCHD5	0.827	0.11
SUOX	COX17	0.824	0.054
THAP4	ZNRF2	0.73	0.096
THAP4	CAMTA1	0.717
ZNRF2	ZNF518B	0.715
CAMTA1	TXN	0.674
THAP4	AIFM1	0.648	0.068
CAMTA1	AK2	0.614
CHCHD4	COX17	0.504	0.108
CAMTA1	ZNRF2	0.427
CAMTA1	CHCHD5	0.415
CAMTA1	COX17	0.415
CAMTA1	GFER	0.381
TXN	HOXB1	0.355
CHCHD5	COX17	0.351	0.236
THAP4	GFER	0.299	0.108
AIFM1	ZNRF2	0.268	0.162
FAM193A	CHCHD5	0.25	0.088
CAMTA1	FAM193A	0.25
GFER	AK2	0.24	0.174
GFER	KPLCE	0.223	0.064
THAP4	CHCHD5	0.214	0.078
GFER	COX17	0.21	0.104
ZNF518B	AK2	0.174
AK2	COX17	0.159	0.166
TXN	ZNRF2	0.152	0.128
ZNF518B	CHCHD5	0.146
THAP4	AK2	0.137	0.042
THAP4	FAM193A	0.131	0.134
TXN	ZNF518B	0.131
FAM193A	COX17	0.117	0.06
AIFM1	ZNF518B	0.112
ZNRF2	COX17	0.108	0.062
SUOX	GFER	0.104	0.056
ZNF518B	COX17	0.098
THAP4	COX17	0.098	0.018
THAP4	TXN	0.093	0.088
CCBE1	TXN	0.081
CHCHD5	KPLCE	0.081	0.034
ZNF518B	KPLCE	0.08
SUOX	CAMTA1	0.078
SUOX	FAM193A	0.076	0.08
ZNF518B	GFER	0.073
SUOX	TXN	0.064	0.1272
TXN	HOXD1	0.063
FAM193A	GFER	0.06	0.118
ZNRF2	AK2	0.057	0.08
CHCHD4	HOXD1	0.053
AIFM1	CHCHD5	0.05	0.13
ZNRF2	CHCHD5	0.046	0.118
SUOX	ZNF518B	0.043
THAP4	SUOX	0.043	0.076
ZNRF2	FAM193A	0.043	0.08
SUOX	ZNRF2	0.042	0.074
TXN	COX17	0.04	0.1
TXN	CHCHD5	0.034	0.094
AK2	CHCHD5	0.031	0.224
TXN	GFER	0.03	0.082
AIFM1	FAM193A	0.028	0.228
SUOX	KPLCE	0.027
ZNRF2	GFER	0.026	0.076
AK2	HOXD1	0.023
FAM193A	ZNF518B	0.022
SUOX	AIFM1	0.022	0.102
AIFM1	HOXD1	0.021
AIFM1	COX17	0.02	0.122
FAM193A	AK2	0.018	0.07
TXN	KPLCE	0.016	0.16
SUOX	AK2	0.015	0.108
ZNRF2	KPLCE	0.006	0.06
TXN	FAM193A	0.006	0.124
TXN	AK2	0.005	0.18
CHCHD4	KPLCE	0.002	0.014
AK2	KPLCE	0.001	0.054
AIFM1	KPLCE	0.0	0.05

Related Complexes

Genename	Complexes
FAM193A	huMAP3_01222.1 huMAP3_03973.1 huMAP3_04194.1 huMAP3_07794.1 huMAP3_08327.1 huMAP3_09002.1 huMAP3_10206.1 huMAP3_11398.1 huMAP3_11535.1 huMAP3_12143.1 huMAP3_13651.1 huMAP3_13966.1
AIFM1	huMAP3_00674.1 huMAP3_01357.1 huMAP3_02200.1 huMAP3_07303.1 huMAP3_08673.1 huMAP3_10541.1 huMAP3_10602.1 huMAP3_11103.1 huMAP3_11535.1
CHCHD4	huMAP3_00674.1 huMAP3_01357.1 huMAP3_03447.1 huMAP3_07303.1 huMAP3_08673.1 huMAP3_10541.1 huMAP3_10602.1 huMAP3_11103.1 huMAP3_11535.1
HOXD1	huMAP3_02824.1 huMAP3_02876.1 huMAP3_04086.1 huMAP3_11103.1 huMAP3_11535.1 huMAP3_14437.1
GFER	huMAP3_01357.1 huMAP3_02200.1 huMAP3_07303.1 huMAP3_08673.1 huMAP3_10602.1 huMAP3_11103.1 huMAP3_11535.1
CHCHD5	huMAP3_02541.1 huMAP3_10389.1 huMAP3_11535.1 huMAP3_12415.1 huMAP3_12514.1 huMAP3_13385.1 huMAP3_13392.1
ZNF518B	huMAP3_01324.1 huMAP3_03102.1 huMAP3_06983.1 huMAP3_07161.1 huMAP3_08472.1 huMAP3_09782.1 huMAP3_10027.1 huMAP3_11535.1 huMAP3_11676.1 huMAP3_13614.1 huMAP3_13717.1
AK2	huMAP3_01357.1 huMAP3_02200.1 huMAP3_02824.1 huMAP3_07303.1 huMAP3_08673.1 huMAP3_10602.1 huMAP3_11103.1 huMAP3_11535.1 huMAP3_14437.1 huMAP3_14499.1
COX17	huMAP3_11285.1 huMAP3_11535.1 huMAP3_12415.1 huMAP3_12514.1 huMAP3_13385.1 huMAP3_14287.1
KPLCE	huMAP3_11535.1 huMAP3_12930.1
THAP4	huMAP3_00205.1 huMAP3_02509.1 huMAP3_09026.1 huMAP3_11535.1 huMAP3_13614.1
ZNRF2	huMAP3_00796.1 huMAP3_06520.1 huMAP3_09326.1 huMAP3_11451.1 huMAP3_11535.1
CCBE1	huMAP3_00037.1 huMAP3_01515.1 huMAP3_02779.1 huMAP3_06014.1 huMAP3_10031.1 huMAP3_10095.1 huMAP3_11535.1 huMAP3_14499.1
SUOX	huMAP3_00380.1 huMAP3_00973.1 huMAP3_06074.1 huMAP3_10198.1 huMAP3_11285.1 huMAP3_11535.1 huMAP3_12415.1 huMAP3_12514.1 huMAP3_13385.1 huMAP3_14287.1
TXN	huMAP3_00674.1 huMAP3_01357.1 huMAP3_03447.1 huMAP3_07303.1 huMAP3_08673.1 huMAP3_10541.1 huMAP3_10602.1 huMAP3_11103.1 huMAP3_11535.1 huMAP3_11922.1
CAMTA1	huMAP3_00674.1 huMAP3_01357.1 huMAP3_03447.1 huMAP3_07303.1 huMAP3_08673.1 huMAP3_10541.1 huMAP3_10602.1 huMAP3_11103.1 huMAP3_11535.1
HOXB1	huMAP3_02824.1 huMAP3_02876.1 huMAP3_04086.1 huMAP3_11103.1 huMAP3_11535.1 huMAP3_12511.1 huMAP3_14437.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_11535.1

Complex Portal: CPX-24811