hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11535.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FAM193A | Protein FAM193A (Protein IT14) | 3 | UniProt NCBI |
| AIFM1 | Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8) | 5 | UniProt NCBI |
| CHCHD4 | Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4) | 5 | UniProt NCBI |
| HOXD1 | Homeobox protein Hox-D1 (Homeobox protein Hox-GG) | 4 | UniProt NCBI |
| GFER | FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration) (hERV1) (Hepatopoietin) | 5 | UniProt NCBI |
| CHCHD5 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 | 3 | UniProt NCBI |
| ZNF518B | Zinc finger protein 518B | 3 | UniProt NCBI |
| AK2 | Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) [Cleaved into: Adenylate kinase 2, mitochondrial, N-terminally processed] | 5 | UniProt NCBI |
| COX17 | Cytochrome c oxidase copper chaperone | 5 | UniProt NCBI |
| KPLCE | Protein KPLCE (KPRP N-terminal and LCE C-terminal-like protein) (Skin-specific protein 32) | 2 | UniProt NCBI |
| THAP4 | Peroxynitrite isomerase THAP4 (EC 5.99.-.-) (Ferric Homo sapiens nitrobindin) (Hs-Nb(III)) (THAP domain-containing protein 4) | 5 | UniProt NCBI |
| ZNRF2 | E3 ubiquitin-protein ligase ZNRF2 (EC 2.3.2.27) (Protein Ells2) (RING finger protein 202) (RING-type E3 ubiquitin transferase ZNRF2) (Zinc/RING finger protein 2) | 5 | UniProt NCBI |
| CCBE1 | Collagen and calcium-binding EGF domain-containing protein 1 (Full of fluid protein homolog) | 5 | UniProt NCBI |
| SUOX | Sulfite oxidase, mitochondrial (EC 1.8.3.1) | 5 | UniProt NCBI |
| TXN | Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx) | 5 | UniProt NCBI |
| CAMTA1 | Calmodulin-binding transcription activator 1 | 5 | UniProt NCBI |
| HOXB1 | Homeobox protein Hox-B1 (Homeobox protein Hox-2I) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1268020 | 0.000101393516557 | 0.266666666667 | GFER COX17 CHCHD4 CHCHD5 | Mitochondrial protein import |
| GO:0005758 | 0.000131261854127 | 0.333333333333 | AIFM1 AK2 COX17 CHCHD4 CHCHD5 | mitochondrial intermembrane space |
| GO:0031970 | 0.000215823179568 | 0.333333333333 | AIFM1 AK2 COX17 CHCHD4 CHCHD5 | organelle envelope lumen |
| REAC:R-HSA-9609507 | 0.00270762753596 | 0.266666666667 | GFER COX17 CHCHD4 CHCHD5 | Protein localization |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| TXN | CHCHD4 | 0.999 | 0.044 |
| AIFM1 | AK2 | 0.999 | 0.47 |
| AIFM1 | CHCHD4 | 0.998 | 0.476 |
| CAMTA1 | CHCHD4 | 0.998 | |
| AIFM1 | GFER | 0.995 | 0.214 |
| CHCHD4 | AK2 | 0.993 | 0.332 |
| CAMTA1 | AIFM1 | 0.992 | |
| HOXD1 | HOXB1 | 0.989 | |
| CHCHD4 | GFER | 0.986 | 0.072 |
| GFER | HOXB1 | 0.985 | |
| AIFM1 | TXN | 0.977 | 0.182 |
| AK2 | HOXB1 | 0.961 | |
| AIFM1 | HOXB1 | 0.959 | |
| CCBE1 | CHCHD4 | 0.95 | |
| CHCHD4 | HOXB1 | 0.95 | |
| CCBE1 | AIFM1 | 0.946 | |
| CHCHD4 | CHCHD5 | 0.919 | 0.112 |
| CHCHD4 | FAM193A | 0.919 | 0.074 |
| THAP4 | CHCHD4 | 0.917 | 0.062 |
| CHCHD4 | ZNRF2 | 0.917 | 0.016 |
| CHCHD4 | ZNF518B | 0.916 | |
| CAMTA1 | ZNF518B | 0.904 | |
| THAP4 | ZNF518B | 0.904 | |
| SUOX | CHCHD4 | 0.875 | 0.086 |
| CCBE1 | AK2 | 0.87 | |
| THAP4 | KPLCE | 0.836 | |
| GFER | CHCHD5 | 0.829 | 0.078 |
| SUOX | CHCHD5 | 0.827 | 0.11 |
| SUOX | COX17 | 0.824 | 0.054 |
| THAP4 | ZNRF2 | 0.73 | 0.096 |
| THAP4 | CAMTA1 | 0.717 | |
| ZNRF2 | ZNF518B | 0.715 | |
| CAMTA1 | TXN | 0.674 | |
| THAP4 | AIFM1 | 0.648 | 0.068 |
| CAMTA1 | AK2 | 0.614 | |
| CHCHD4 | COX17 | 0.504 | 0.108 |
| CAMTA1 | ZNRF2 | 0.427 | |
| CAMTA1 | COX17 | 0.415 | |
| CAMTA1 | CHCHD5 | 0.415 | |
| CAMTA1 | GFER | 0.381 | |
| TXN | HOXB1 | 0.355 | |
| CHCHD5 | COX17 | 0.351 | 0.236 |
| THAP4 | GFER | 0.299 | 0.108 |
| AIFM1 | ZNRF2 | 0.268 | 0.162 |
| CAMTA1 | FAM193A | 0.25 | |
| FAM193A | CHCHD5 | 0.25 | 0.088 |
| GFER | AK2 | 0.24 | 0.174 |
| GFER | KPLCE | 0.223 | 0.064 |
| THAP4 | CHCHD5 | 0.214 | 0.078 |
| GFER | COX17 | 0.21 | 0.104 |
| ZNF518B | AK2 | 0.174 | |
| AK2 | COX17 | 0.159 | 0.166 |
| TXN | ZNRF2 | 0.152 | 0.128 |
| ZNF518B | CHCHD5 | 0.146 | |
| THAP4 | AK2 | 0.137 | 0.042 |
| THAP4 | FAM193A | 0.131 | 0.134 |
| TXN | ZNF518B | 0.131 | |
| FAM193A | COX17 | 0.117 | 0.06 |
| AIFM1 | ZNF518B | 0.112 | |
| ZNRF2 | COX17 | 0.108 | 0.062 |
| SUOX | GFER | 0.104 | 0.056 |
| THAP4 | COX17 | 0.098 | 0.018 |
| ZNF518B | COX17 | 0.098 | |
| THAP4 | TXN | 0.093 | 0.088 |
| CCBE1 | TXN | 0.081 | |
| CHCHD5 | KPLCE | 0.081 | 0.034 |
| ZNF518B | KPLCE | 0.08 | |
| SUOX | CAMTA1 | 0.078 | |
| SUOX | FAM193A | 0.076 | 0.08 |
| ZNF518B | GFER | 0.073 | |
| SUOX | TXN | 0.064 | 0.1272 |
| TXN | HOXD1 | 0.063 | |
| FAM193A | GFER | 0.06 | 0.118 |
| ZNRF2 | AK2 | 0.057 | 0.08 |
| CHCHD4 | HOXD1 | 0.053 | |
| AIFM1 | CHCHD5 | 0.05 | 0.13 |
| ZNRF2 | CHCHD5 | 0.046 | 0.118 |
| SUOX | ZNF518B | 0.043 | |
| ZNRF2 | FAM193A | 0.043 | 0.08 |
| THAP4 | SUOX | 0.043 | 0.076 |
| SUOX | ZNRF2 | 0.042 | 0.074 |
| TXN | COX17 | 0.04 | 0.1 |
| TXN | CHCHD5 | 0.034 | 0.094 |
| AK2 | CHCHD5 | 0.031 | 0.224 |
| TXN | GFER | 0.03 | 0.082 |
| AIFM1 | FAM193A | 0.028 | 0.228 |
| SUOX | KPLCE | 0.027 | |
| ZNRF2 | GFER | 0.026 | 0.076 |
| AK2 | HOXD1 | 0.023 | |
| FAM193A | ZNF518B | 0.022 | |
| SUOX | AIFM1 | 0.022 | 0.102 |
| AIFM1 | HOXD1 | 0.021 | |
| AIFM1 | COX17 | 0.02 | 0.122 |
| FAM193A | AK2 | 0.018 | 0.07 |
| TXN | KPLCE | 0.016 | 0.16 |
| SUOX | AK2 | 0.015 | 0.108 |
| ZNRF2 | KPLCE | 0.006 | 0.06 |
| TXN | FAM193A | 0.006 | 0.124 |
| TXN | AK2 | 0.005 | 0.18 |
| CHCHD4 | KPLCE | 0.002 | 0.014 |
| AK2 | KPLCE | 0.001 | 0.054 |
| AIFM1 | KPLCE | 0.0 | 0.05 |
Related Complexes