hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11593.1
Complex Portal: CPX-18348
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ABCB9 | ABC-type oligopeptide transporter ABCB9 (EC 7.4.2.6) (ATP-binding cassette sub-family B member 9) (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL) | 5 | UniProt NCBI |
| KCNT2 | Potassium channel subfamily T member 2 (Sequence like an intermediate conductance potassium channel subunit) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1) | 5 | UniProt NCBI |
| SLC43A1 | Large neutral amino acids transporter small subunit 3 (L-type amino acid transporter 3) (Prostate cancer overexpressed gene 1 protein) (Solute carrier family 43 member 1) | 5 | UniProt NCBI |
| PIGQ | Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (N-acetylglucosamyl transferase component GPI1) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) | 5 | UniProt NCBI |
| MARCHF4 | E3 ubiquitin-protein ligase MARCHF4 (EC 2.3.2.27) (Membrane-associated RING finger protein 4) (Membrane-associated RING-CH protein IV) (MARCH-IV) (RING finger protein 174) (RING-type E3 ubiquitin transferase MARCHF4) | 5 | UniProt NCBI |
| ANO10 | Anoctamin-10 (Transmembrane protein 16K) | 5 | UniProt NCBI |
| LRRC8D | Volume-regulated anion channel subunit LRRC8D (Leucine-rich repeat-containing protein 5) (Leucine-rich repeat-containing protein 8D) (HsLRRC8D) | 5 | UniProt NCBI |
| SLC17A2 | Sodium-dependent phosphate transport protein 3 (Na(+)/PI cotransporter 3) (Sodium/phosphate cotransporter 3) (Solute carrier family 17 member 2) | 5 | UniProt NCBI |
| ABCD4 | Lysosomal cobalamin transporter ABCD4 (EC 7.6.2.8) (ATP-binding cassette sub-family D member 4) (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0022857 | 0.000857921652942 | 0.777777777778 | SLC17A2 LRRC8D ABCD4 SLC43A1 KCNT2 ABCB9 ANO10 | transmembrane transporter activity |
| GO:0005215 | 0.00188245805208 | 0.777777777778 | SLC17A2 LRRC8D ABCD4 SLC43A1 KCNT2 ABCB9 ANO10 | transporter activity |
| KEGG:02010 | 0.00946371194657 | 0.222222222222 | ABCB9 ABCD4 | ABC transporters |
| REAC:R-HSA-382551 | 0.0451212027851 | 0.444444444444 | LRRC8D ABCB9 ANO10 SLC43A1 | Transport of small molecules |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SLC17A2 | ANO10 | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SLC17A2 | SLC43A1 | 0.989 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| KCNT2 | SLC17A2 | 0.973 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SLC17A2 | ABCD4 | 0.955 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ABCB9 | SLC17A2 | 0.95 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MARCHF4 | KCNT2 | 0.946 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| LRRC8D | SLC17A2 | 0.923 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ABCB9 | MARCHF4 | 0.908 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MARCHF4 | PIGQ | 0.89 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ABCB9 | PIGQ | 0.829 | bioplex3_WMM WMM_only | ||
| MARCHF4 | ABCD4 | 0.795 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KCNT2 | ABCD4 | 0.676 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ABCB9 | ANO10 | 0.643 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| KCNT2 | ANO10 | 0.607 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ANO10 | ABCD4 | 0.56 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only | |
| ABCB9 | ABCD4 | 0.554 | bioplex_WMM bioplex3_WMM WMM_only | ||
| LRRC8D | KCNT2 | 0.446 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ABCB9 | KCNT2 | 0.421 | bioplex_WMM bioplex3_WMM WMM_only | ||
| LRRC8D | ANO10 | 0.387 | 0.036 | bioplex_WMM bioplex3_WMM WMM_only | |
| PIGQ | ABCD4 | 0.335 | 0.072 | bioplex_WMM bioplex3_WMM WMM_only | |
| ABCB9 | LRRC8D | 0.328 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KCNT2 | PIGQ | 0.284 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ANO10 | SLC43A1 | 0.265 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only | |
| LRRC8D | SLC43A1 | 0.262 | 0.144 | bioplex_WMM bioplex3_WMM WMM_only | |
| SLC43A1 | ABCD4 | 0.237 | 0.132 | bioplex_WMM bioplex3_WMM WMM_only | |
| LRRC8D | ABCD4 | 0.233 | 0.084 | bioplex_WMM bioplex3_WMM WMM_only | |
| ABCB9 | SLC43A1 | 0.165 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KCNT2 | SLC43A1 | 0.165 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PIGQ | SLC43A1 | 0.085 | 0.086 | bioplex3_WMM WMM_only | |
| ANO10 | PIGQ | 0.079 | 0.058 | bioplex3_WMM WMM_only | |
| LRRC8D | PIGQ | 0.079 | 0.102 | bioplex3_WMM WMM_only |
Related Complexes