hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11609.1
Complex Portal: CPX-24741
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CCDC185 | Coiled-coil domain-containing protein 185 | 5 | UniProt NCBI |
| BFSP1 | Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H) [Cleaved into: Filensin C-terminal fragment; Filensin N-terminal fragment] | 5 | UniProt NCBI |
| MPHOSPH9 | M-phase phosphoprotein 9 | 5 | UniProt NCBI |
| BFSP2 | Phakinin (49 kDa cytoskeletal protein) (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 47) (CP47) (Lens fiber cell beaded filament protein CP 49) (CP49) (Lens intermediate filament-like light) (LIFL-L) | 5 | UniProt NCBI |
| CENPE | Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-7) (Kinesin-related protein CENPE) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0200291 | 0.00085197326798 | 0.4 | BFSP1 BFSP2 | eye; lens fiber cells[>=Low] |
| HPA:0200292 | 0.00085197326798 | 0.4 | BFSP1 BFSP2 | eye; lens fiber cells[>=Medium] |
| HPA:0200000 | 0.00170254701487 | 0.4 | BFSP1 BFSP2 | eye |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BFSP1 | BFSP2 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| CENPE | BFSP2 | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM | ||
| CCDC185 | BFSP1 | 0.99 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| BFSP1 | MPHOSPH9 | 0.871 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CENPE | BFSP1 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CCDC185 | MPHOSPH9 | 0.046 | bioplex3_WMM WMM_only | ||
| CENPE | MPHOSPH9 | 0.005 | gupta_WMM WMM_only |
Related Complexes