hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_11653.1

Complex Portal: CPX-16401

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
DNMT1	DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT)	5	UniProt NCBI
HMGB2	High mobility group protein B2 (High mobility group protein 2) (HMG-2)	5	UniProt NCBI
CALD1	Caldesmon (CDM)	5	UniProt NCBI
ZBTB6	Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482) (Zinc finger protein with interaction domain)	5	UniProt NCBI
CNN3	Calponin-3 (Calponin, acidic isoform)	5	UniProt NCBI
TACO1	Translational activator of cytochrome c oxidase 1 (Coiled-coil domain-containing protein 44) (Translational activator of mitochondrially-encoded cytochrome c oxidase I)	5	UniProt NCBI
EIF4B	Eukaryotic translation initiation factor 4B (eIF-4B)	5	UniProt NCBI
FAM50A	Protein FAM50A (Protein HXC-26) (Protein XAP-5)	5	UniProt NCBI
API5	Apoptosis inhibitor 5 (API-5) (Antiapoptosis clone 11 protein) (AAC-11) (Cell migration-inducing gene 8 protein) (Fibroblast growth factor 2-interacting factor) (FIF) (Protein XAGL)	5	UniProt NCBI
LRRC47	Leucine-rich repeat-containing protein 47	4	UniProt NCBI
RTF2	Replication termination factor 2 (RTF2) (Replication termination factor 2 domain-containing protein 1)	5	UniProt NCBI
HMGB1	High mobility group protein B1 (High mobility group protein 1) (HMG-1)	5	UniProt NCBI
PLEK	Pleckstrin (Platelet 47 kDa protein) (p47)	5	UniProt NCBI
MAP4	Microtubule-associated protein 4 (MAP-4)	5	UniProt NCBI
FAM50B	Protein FAM50B (Protein XAP-5-like)	5	UniProt NCBI
HMGB3	High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4)	5	UniProt NCBI
EDF1	Endothelial differentiation-related factor 1 (EDF-1) (Multiprotein-bridging factor 1) (MBF1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:280	0.000153131458895	0.125	HMGB2 HMGB1	HMGB1-HMGB2-HSC70-ERP60-GAPDH complex
HPA:0470203	0.00211633200245	0.3125	MAP4 HMGB2 HMGB1 CNN3 CALD1	skin 2; endothelial cells[High]
GO:0008301	0.00883419058623	0.1875	HMGB2 HMGB1 HMGB3	DNA binding, bending
HPA:0570772	0.017496559506	0.3125	HMGB1 HMGB2 FAM50A CNN3 CALD1	testis; peritubular cells[>=Medium]
HPA:0400203	0.018800257384	0.1875	HMGB2 CNN3 HMGB1	rectum; endothelial cells[High]
HPA:0460201	0.0202762750188	0.375	CALD1 MAP4 HMGB2 TACO1 CNN3 HMGB1	skin 1; endothelial cells[>=Low]
REAC:R-HSA-140342	0.0254483747841	0.125	HMGB2 HMGB1	Apoptosis induced DNA fragmentation
HPA:0470201	0.027151466016	0.375	CALD1 MAP4 HMGB2 TACO1 CNN3 HMGB1	skin 2; endothelial cells[>=Low]
HPA:0480892	0.0353490287693	0.25	PLEK HMGB2 CNN3 HMGB1	small intestine; goblet cells[>=Medium]
GO:0000400	0.0362620408935	0.1875	HMGB2 HMGB1 HMGB3	four-way junction DNA binding
HPA:0460202	0.0409462266924	0.3125	MAP4 HMGB2 HMGB1 CNN3 CALD1	skin 1; endothelial cells[>=Medium]
HPA:0460203	0.0419040356452	0.25	MAP4 HMGB2 HMGB1 CALD1	skin 1; endothelial cells[High]
HPA:0471493	0.0489729701894	0.1875	HMGB2 HMGB1 CALD1	skin 2; vascular mural cells[High]

Edges

Protein 1	Protein 2	Score	ProteomeHD
MAP4	CALD1	0.985
RTF2	DNMT1	0.981	0.206
HMGB1	HMGB2	0.972	0.722
API5	CALD1	0.962
FAM50A	EDF1	0.954	0.14
CALD1	HMGB3	0.927
HMGB3	FAM50A	0.922	0.126
HMGB3	LRRC47	0.921	0.1
FAM50A	FAM50B	0.919
RTF2	FAM50A	0.916	0.076
CALD1	FAM50A	0.913
HMGB1	HMGB3	0.9	0.33
CALD1	HMGB1	0.898
DNMT1	LRRC47	0.896	0.108
CALD1	LRRC47	0.892
RTF2	HMGB3	0.886	0.074
CNN3	PLEK	0.883	0.234
MAP4	LRRC47	0.881
HMGB2	LRRC47	0.879	0.222
CALD1	CNN3	0.877
FAM50A	ZBTB6	0.869
HMGB2	HMGB3	0.866	0.37
API5	FAM50A	0.856	0.268
API5	LRRC47	0.855	0.222
DNMT1	HMGB3	0.848	0.106
RTF2	TACO1	0.848	0.074
CALD1	RTF2	0.844
CALD1	EIF4B	0.843
CALD1	EDF1	0.834
CALD1	HMGB2	0.83
MAP4	CNN3	0.83
API5	HMGB3	0.819	0.11
RTF2	LRRC47	0.783	0.028
MAP4	EIF4B	0.772
HMGB1	FAM50A	0.752	0.132
API5	DNMT1	0.718	0.318
FAM50A	LRRC47	0.715	0.176
HMGB1	LRRC47	0.708	0.228
CALD1	DNMT1	0.698
RTF2	CNN3	0.687	0.056
CALD1	TACO1	0.675
HMGB1	TACO1	0.673	0.094
EIF4B	LRRC47	0.666	0.172
CNN3	LRRC47	0.653	0.102
DNMT1	FAM50A	0.647	0.128
FAM50A	EIF4B	0.639	0.268
EDF1	LRRC47	0.637	0.212
FAM50A	TACO1	0.569	0.044
HMGB3	EDF1	0.564	0.09
HMGB2	DNMT1	0.553	0.176
HMGB3	TACO1	0.533	0.058
TACO1	LRRC47	0.505	0.11
API5	HMGB2	0.493	0.326
MAP4	HMGB3	0.482
API5	EIF4B	0.462	0.334
RTF2	EDF1	0.427	0.06
HMGB3	CNN3	0.407	0.074
DNMT1	TACO1	0.35	0.092
CNN3	EIF4B	0.336	0.206
EDF1	EIF4B	0.314	0.19
DNMT1	EDF1	0.307	0.154
MAP4	FAM50A	0.298
MAP4	DNMT1	0.284
HMGB2	EIF4B	0.281	0.242
MAP4	HMGB2	0.235
RTF2	EIF4B	0.234	0.278
API5	MAP4	0.23
MAP4	EDF1	0.209
RTF2	HMGB1	0.201	0.06
HMGB2	FAM50A	0.188	0.094
MAP4	TACO1	0.187
HMGB2	EDF1	0.157	0.146
API5	EDF1	0.155	0.22
HMGB1	DNMT1	0.148	0.2
HMGB3	EIF4B	0.145	0.068
MAP4	HMGB1	0.136
MAP4	RTF2	0.128
HMGB2	TACO1	0.127	0.06
API5	RTF2	0.124	0.136
DNMT1	CNN3	0.119	0.094
API5	TACO1	0.097	0.092
CNN3	TACO1	0.096	0.048
RTF2	HMGB2	0.082	0.024
API5	HMGB1	0.081	0.39
EDF1	TACO1	0.077	0.078
DNMT1	EIF4B	0.074	0.092
TACO1	EIF4B	0.052	0.124
FAM50A	CNN3	0.05	0.116
API5	CNN3	0.041	0.172
HMGB1	EIF4B	0.04	0.204
EDF1	ZBTB6	0.038
EDF1	CNN3	0.032	0.134
PLEK	TACO1	0.028	0.054
HMGB2	ZBTB6	0.028
HMGB1	EDF1	0.027	0.07
HMGB1	CNN3	0.015	0.238
EDF1	PLEK	0.014	0.032
HMGB3	ZBTB6	0.014
CALD1	ZBTB6	0.012
HMGB2	PLEK	0.011	0.094
EIF4B	ZBTB6	0.01
DNMT1	ZBTB6	0.009
MAP4	ZBTB6	0.009
LRRC47	FAM50B	0.008
CNN3	ZBTB6	0.007
HMGB1	PLEK	0.007	0.136
API5	ZBTB6	0.007
PLEK	EIF4B	0.005	0.116
HMGB2	CNN3	0.003	0.194
HMGB1	ZBTB6	0.002
MAP4	PLEK	0.002

Related Complexes

Genename	Complexes
DNMT1	huMAP3_01087.1 huMAP3_02973.1 huMAP3_05472.1 huMAP3_08171.1 huMAP3_11653.1 huMAP3_13283.1 huMAP3_13998.1 huMAP3_14982.1
HMGB2	huMAP3_00806.1 huMAP3_08690.1 huMAP3_10093.1 huMAP3_11653.1 huMAP3_12523.1 huMAP3_14618.1
CALD1	huMAP3_00227.1 huMAP3_02119.1 huMAP3_03762.1 huMAP3_06395.1 huMAP3_10673.1 huMAP3_11074.1 huMAP3_11653.1 huMAP3_12523.1
ZBTB6	huMAP3_11653.1 huMAP3_13283.1 huMAP3_14041.1 huMAP3_14675.1 huMAP3_14750.1
CNN3	huMAP3_01619.1 huMAP3_11653.1 huMAP3_11859.1
TACO1	huMAP3_11391.1 huMAP3_11653.1 huMAP3_12535.1 huMAP3_13103.1 huMAP3_13283.1 huMAP3_13411.1
EIF4B	huMAP3_11429.1 huMAP3_11653.1 huMAP3_12523.1 huMAP3_14832.1
FAM50A	huMAP3_01587.1 huMAP3_11653.1 huMAP3_12523.1 huMAP3_13283.1 huMAP3_14750.1
API5	huMAP3_00227.1 huMAP3_02119.1 huMAP3_03762.1 huMAP3_06395.1 huMAP3_10673.1 huMAP3_11074.1 huMAP3_11293.1 huMAP3_11653.1 huMAP3_12523.1 huMAP3_13283.1 huMAP3_14618.1 huMAP3_14750.1 huMAP3_14982.1
LRRC47	huMAP3_11653.1 huMAP3_12523.1 huMAP3_13283.1 huMAP3_14618.1 huMAP3_14982.1
RTF2	huMAP3_00559.1 huMAP3_02973.1 huMAP3_08171.1 huMAP3_10737.1 huMAP3_11653.1 huMAP3_12523.1 huMAP3_13283.1
HMGB1	huMAP3_00806.1 huMAP3_06127.1 huMAP3_08690.1 huMAP3_10049.1 huMAP3_11653.1 huMAP3_12437.1 huMAP3_12523.1 huMAP3_14618.1
PLEK	huMAP3_03603.1 huMAP3_11653.1 huMAP3_11859.1
MAP4	huMAP3_00227.1 huMAP3_02119.1 huMAP3_03762.1 huMAP3_06395.1 huMAP3_10673.1 huMAP3_11074.1 huMAP3_11653.1 huMAP3_11859.1 huMAP3_12523.1
FAM50B	huMAP3_11653.1 huMAP3_12523.1 huMAP3_13283.1 huMAP3_14750.1
HMGB3	huMAP3_01252.1 huMAP3_05512.1 huMAP3_08901.1 huMAP3_11653.1 huMAP3_12523.1 huMAP3_13283.1 huMAP3_14618.1 huMAP3_14750.1
EDF1	huMAP3_01587.1 huMAP3_11653.1 huMAP3_12523.1 huMAP3_13283.1 huMAP3_14750.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_11653.1

Complex Portal: CPX-16401