hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11662.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CTSC | Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] | 5 | UniProt NCBI |
| WFDC9 | Protein WFDC9 | 2 | UniProt NCBI |
| CST3 | Cystatin-C (Cystatin-3) (Gamma-trace) (Neuroendocrine basic polypeptide) (Post-gamma-globulin) | 5 | UniProt NCBI |
| GFRA3 | GDNF family receptor alpha-3 (GDNF receptor alpha-3) (GDNFR-alpha-3) (GFR-alpha-3) | 5 | UniProt NCBI |
| CTSL | Procathepsin L (EC 3.4.22.15) (Cathepsin L1) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L; Cathepsin L heavy chain; Cathepsin L light chain] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0271143 | 0.00454527080883 | 0.6 | CTSC CTSL CST3 | kidney; proximal tubules (cell body)[High] |
| GO:0060309 | 0.0140440992017 | 0.4 | CST3 CTSL | elastin catabolic process |
| KEGG:04210 | 0.0319348346673 | 0.4 | CTSC CTSL | Apoptosis |
| HPA:0271142 | 0.0324319514824 | 0.6 | CTSC CTSL CST3 | kidney; proximal tubules (cell body)[>=Medium] |
| KEGG:04142 | 0.0335445792486 | 0.4 | CTSC CTSL | Lysosome |
| GO:0051541 | 0.0468008499735 | 0.4 | CST3 CTSL | elastin metabolic process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CTSL | CST3 | 0.998 | 0.104 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 fraction |
| CTSC | CST3 | 0.981 | 0.242 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| CTSC | WFDC9 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CTSC | CTSL | 0.936 | 0.140454545455 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CST3 | GFRA3 | 0.902 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes