hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11663.1
Complex Portal: CPX-14415
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RLN2 | Prorelaxin H2 [Cleaved into: Relaxin B chain; Relaxin A chain] | 5 | UniProt NCBI |
| NMS | Neuromedin-S | 3 | UniProt NCBI |
| BACE1 | Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2) | 5 | UniProt NCBI |
| COL14A1 | Collagen alpha-1(XIV) chain (Undulin) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04080 | 0.0428875882852 | 0.5 | NMS RLN2 | Neuroactive ligand-receptor interaction |
| REAC:R-HSA-375276 | 0.046351696636 | 0.5 | NMS RLN2 | Peptide ligand-binding receptors |
| CORUM:4039 | 0.049938562206 | 0.25 | BACE1 | PAR4-BACE1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NMS | BACE1 | 0.983 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| COL14A1 | RLN2 | 0.831 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| COL14A1 | NMS | 0.801 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| BACE1 | RLN2 | 0.113 | bioplex3_WMM WMM_only | ||
| COL14A1 | BACE1 | 0.079 | bioplex3_WMM WMM_only |
Related Complexes