hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11687.1
Complex Portal: CPX-23199
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-hydroxyanthranilate oxygenase) (3-HAO) (h3HAO) (3-hydroxyanthranilic acid dioxygenase) (HAD) | 5 | UniProt NCBI |
| VWC2L | von Willebrand factor C domain-containing protein 2-like (VWC2-like protein) (Brorin-like) | 5 | UniProt NCBI |
| MTURN | Maturin (Maturin neural progenitor differentiation regulator protein homolog) (Protein Ells1) | 5 | UniProt NCBI |
| DAZAP1 | DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1) | 5 | UniProt NCBI |
| GCLC | Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) | 5 | UniProt NCBI |
| TYW3 | tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase) | 4 | UniProt NCBI |
| LYZL6 | Lysozyme-like protein 6 (EC 3.2.1.17) | 5 | UniProt NCBI |
| MTAP | S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00270 | 0.0132732043194 | 0.25 | GCLC MTAP | Cysteine and methionine metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TYW3 | MTAP | 0.993 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TYW3 | GCLC | 0.963 | 0.05 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TYW3 | MTURN | 0.948 | 0.08 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only |
| TYW3 | VWC2L | 0.862 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| TYW3 | LYZL6 | 0.846 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MTAP | HAAO | 0.839 | 0.136 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TYW3 | DAZAP1 | 0.817 | 0.052 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MTAP | GCLC | 0.74 | 0.06 | bioplex_WMM bioplex3_WMM fraction | |
| GCLC | DAZAP1 | 0.127 | 0.054 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MTURN | DAZAP1 | 0.101 | 0.098 | bioplex3_HEK293 WMM_only | |
| VWC2L | DAZAP1 | 0.055 | bioplex3_HEK293 WMM_only | ||
| MTAP | DAZAP1 | 0.01 | 0.078 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| GCLC | HAAO | 0.009 | 0.102 | fraction | |
| MTAP | LYZL6 | 0.003 | bioplex3_HCT116 WMM_only |
Related Complexes