hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11693.1
Complex Portal: CPX-16202
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KATNA1 | Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 5.6.1.1) (p60 katanin) | 5 | UniProt NCBI |
| KATNAL1 | Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (EC 5.6.1.1) (p60 katanin-like 1) | 5 | UniProt NCBI |
| MCRIP2 | MAPK regulated corepressor interacting protein 2 (Protein FAM195A) | 4 | UniProt NCBI |
| MCRIP1 | Mapk-regulated corepressor-interacting protein 1 (Granulin-2) (Protein FAM195B) | 5 | UniProt NCBI |
| KATNBL1 | KATNB1-like protein 1 (Katanin p80 subunit B-like 1) | 5 | UniProt NCBI |
| KATNB1 | Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin) | 5 | UniProt NCBI |
| LSM12 | Protein LSM12 | 5 | UniProt NCBI |
| ATXN2L | Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7366 | 3.36110250117e-12 | 0.5 | KATNB1 KATNBL1 KATNA1 KATNAL1 | KATNA1-KATNAL1-KATNB1-KATNBL1 complex |
| GO:0008352 | 1.84188417064e-09 | 0.5 | KATNB1 KATNBL1 KATNA1 KATNAL1 | katanin complex |
| GO:0031122 | 0.000247854455944 | 0.5 | KATNB1 KATNBL1 KATNA1 KATNAL1 | cytoplasmic microtubule organization |
| GO:0000922 | 0.0152505613645 | 0.5 | KATNB1 KATNBL1 KATNA1 KATNAL1 | spindle pole |
| GO:0005875 | 0.0162903522249 | 0.5 | KATNB1 KATNBL1 KATNA1 KATNAL1 | microtubule associated complex |
| GO:0051013 | 0.0393180950424 | 0.25 | KATNA1 KATNAL1 | microtubule severing |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KATNA1 | KATNB1 | 1.0 | 0.094 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM |
| LSM12 | ATXN2L | 1.0 | 0.514 |
structurally_consistent (dimer)
|
youn () bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| MCRIP2 | LSM12 | 1.0 | 0.146 |
structurally_consistent (dimer)
|
youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| MCRIP2 | ATXN2L | 0.999 | 0.09 |
mutually_exclusive (Q3MHD2)
|
youn () bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| KATNA1 | KATNBL1 | 0.998 | 0.146 |
mixed_interface
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 boldt_WMM |
| KATNBL1 | KATNAL1 | 0.998 | 0.08 |
structurally_consistent (Q9BVA0)
|
bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only |
| KATNB1 | KATNBL1 | 0.994 | 0.082 |
mixed_interface
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM |
| MCRIP1 | LSM12 | 0.968 | 0.03 | youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM | |
| ATXN2L | KATNBL1 | 0.954 | 0.046 | bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only | |
| LSM12 | KATNBL1 | 0.933 | 0.084 | bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only | |
| KATNA1 | KATNAL1 | 0.911 | 0.078 | bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only | |
| MCRIP1 | KATNBL1 | 0.886 | 0.056 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KATNB1 | KATNAL1 | 0.797 | 0.08 |
structurally_consistent (dimer)
|
bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only |
| KATNA1 | MCRIP1 | 0.307 | 0.036 | bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| MCRIP1 | KATNAL1 | 0.283 | 0.062 | bioplex3_WMM youn_WMM WMM_only | |
| MCRIP2 | MCRIP1 | 0.228 | 0.026 | youn () bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| LSM12 | KATNAL1 | 0.223 | 0.028 | bioplex3_WMM boldt youn_WMM fraction boldt_WMM | |
| KATNB1 | MCRIP1 | 0.157 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| KATNB1 | LSM12 | 0.085 | 0.048 | bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | |
| ATXN2L | KATNAL1 | 0.082 | 0.086 | bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM | |
| MCRIP1 | ATXN2L | 0.081 | 0.016 | bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM | |
| KATNB1 | ATXN2L | 0.066 | 0.032 | bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | |
| KATNA1 | ATXN2L | 0.053 | 0.16 | bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM | |
| KATNA1 | LSM12 | 0.038 | 0.15 | bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | |
| KATNA1 | MCRIP2 | 0.017 | 0.058 | youn_WMM WMM_only | |
| MCRIP2 | KATNAL1 | 0.01 | 0.044 | youn_WMM WMM_only | |
| KATNB1 | MCRIP2 | 0.005 | 0.082 | youn () youn_WMM WMM_only |
Related Complexes