hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11699.1
Complex Portal: CPX-21433
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DUSP2 | Dual specificity protein phosphatase 2 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PAC-1) | 5 | UniProt NCBI |
| SYN3 | Synapsin-3 (Synapsin III) | 5 | UniProt NCBI |
| HPCAL4 | Hippocalcin-like protein 4 (HLP4) | 5 | UniProt NCBI |
| NDRG4 | Protein NDRG4 (Brain development-related molecule 1) (N-myc downstream-regulated gene 4 protein) (Vascular smooth muscle cell-associated protein 8) (SMAP-8) | 5 | UniProt NCBI |
| MAP2 | Microtubule-associated protein 2 (MAP-2) | 5 | UniProt NCBI |
| SYN2 | Synapsin-2 (Synapsin II) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-181429 | 0.0018206657072 | 0.4 | SYN2 SYN3 | Serotonin Neurotransmitter Release Cycle |
| REAC:R-HSA-212676 | 0.00318398402781 | 0.4 | SYN2 SYN3 | Dopamine Neurotransmitter Release Cycle |
| WP:WP2267 | 0.00528162918062 | 0.4 | SYN2 SYN3 | Synaptic vesicle pathway |
| REAC:R-HSA-112310 | 0.0106339701454 | 0.4 | SYN2 SYN3 | Neurotransmitter release cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SYN2 | DUSP2 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SYN3 | SYN2 | 0.97 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MAP2 | NDRG4 | 0.845 | bioplex_WMM bioplex3_WMM WMM_only | ||
| HPCAL4 | NDRG4 | 0.845 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SYN2 | NDRG4 | 0.845 | bioplex_WMM bioplex3_WMM WMM_only | ||
| HPCAL4 | SYN2 | 0.845 | bioplex_WMM bioplex3_WMM WMM_only | ||
| MAP2 | HPCAL4 | 0.845 | bioplex_WMM bioplex3_WMM WMM_only | ||
| MAP2 | SYN2 | 0.738 | 0.0942127659574 | bioplex_WMM bioplex3_WMM WMM_only | |
| SYN3 | DUSP2 | 0.218 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SYN3 | NDRG4 | 0.027 | bioplex3_WMM WMM_only | ||
| HPCAL4 | SYN3 | 0.027 | bioplex3_WMM WMM_only | ||
| MAP2 | SYN3 | 0.027 | bioplex3_WMM WMM_only |
Related Complexes