hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11707.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LYSMD1 | LysM and putative peptidoglycan-binding domain-containing protein 1 | 4 | UniProt NCBI |
| AKT1S1 | Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate) | 5 | UniProt NCBI |
| HSPG2 | Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide] | 5 | UniProt NCBI |
| TUB | Tubby protein homolog | 5 | UniProt NCBI |
| RNF138 | E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138) | 5 | UniProt NCBI |
| TULP1 | Tubby-related protein 1 (Tubby-like protein 1) | 5 | UniProt NCBI |
| ANKRD54 | Ankyrin repeat domain-containing protein 54 (Lyn-interacting ankyrin repeat protein) | 3 | UniProt NCBI |
| SMYD5 | Histone-lysine N-trimethyltransferase SMYD5 (EC 2.1.1.372) (Protein NN8-4AG) (Retinoic acid-induced protein 15) (SET and MYND domain-containing protein 5) ([histone H4]-lysine20 N-trimethyltransferase SMYD5) | 5 | UniProt NCBI |
| TULP3 | Tubby-related protein 3 (Tubby-like protein 3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0500087 | 0.0238199336716 | 0.222222222222 | TUB TULP1 | Peripapillary atrophy |
| HP:0012512 | 0.0277810467869 | 0.222222222222 | TUB TULP1 | Diffuse optic disc pallor |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ANKRD54 | TULP3 | 0.998 | 0.106 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM |
| TULP1 | TULP3 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| LYSMD1 | TULP3 | 0.994 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| TUB | TULP3 | 0.98 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TULP3 | HSPG2 | 0.977 | 0.11 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| RNF138 | TULP3 | 0.96 | 0.137111111111 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| SMYD5 | TUB | 0.903 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ANKRD54 | TUB | 0.848 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| AKT1S1 | TULP3 | 0.812 | 0.102 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| LYSMD1 | TULP1 | 0.557 | bioplex_WMM bioplex3_WMM WMM_only | |
| AKT1S1 | LYSMD1 | 0.502 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only |
| AKT1S1 | TULP1 | 0.502 | bioplex_WMM bioplex3_WMM WMM_only | |
| LYSMD1 | TUB | 0.487 | bioplex_WMM bioplex3_WMM WMM_only | |
| TUB | TULP1 | 0.487 | bioplex_WMM bioplex3_WMM WMM_only | |
| ANKRD54 | LYSMD1 | 0.35 | 0.104 | bioplex_WMM bioplex3_WMM WMM_only |
| ANKRD54 | TULP1 | 0.305 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| ANKRD54 | AKT1S1 | 0.189 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only |
| RNF138 | TUB | 0.166 | bioplex_WMM bioplex3_WMM WMM_only | |
| AKT1S1 | TUB | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | |
| ANKRD54 | RNF138 | 0.162 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only |
| RNF138 | TULP1 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | |
| RNF138 | LYSMD1 | 0.143 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only |
| AKT1S1 | RNF138 | 0.125 | 0.08 | bioplex_WMM bioplex3_WMM WMM_only |
| ANKRD54 | HSPG2 | 0.099 | 0.022 | bioplex3_WMM WMM_only |
| TULP1 | HSPG2 | 0.055 | bioplex3_WMM WMM_only | |
| LYSMD1 | HSPG2 | 0.055 | 0.072 | bioplex3_WMM WMM_only |
| TUB | HSPG2 | 0.042 | bioplex3_WMM WMM_only | |
| AKT1S1 | HSPG2 | 0.03 | 0.052 | bioplex3_WMM WMM_only |
| RNF138 | HSPG2 | 0.016 | 0.088 | bioplex3_WMM WMM_only |
Related Complexes