hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11712.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PGAM4 | Probable phosphoglycerate mutase 4 (EC 5.4.2.11) (EC 5.4.2.4) | 4 | UniProt NCBI |
| BPGM | Bisphosphoglycerate mutase (BPGM) (EC 5.4.2.4) (2,3-bisphosphoglycerate mutase, erythrocyte) (2,3-bisphosphoglycerate synthase) (EC 5.4.2.11) (2,3-diphosphoglycerate mutase) (DPGM) (BPG-dependent PGAM) | 5 | UniProt NCBI |
| PGAM1 | Phosphoglycerate mutase 1 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B) | 5 | UniProt NCBI |
| KLF16 | Krueppel-like factor 16 (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor BTEB4) (Transcription factor NSLP2) | 4 | UniProt NCBI |
| PGAM2 | Phosphoglycerate mutase 2 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase) (Phosphoglycerate mutase isozyme M) (PGAM-M) | 5 | UniProt NCBI |
| SPACA9 | Sperm acrosome-associated protein 9 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00260 | 5.07589472875e-06 | 0.6 | PGAM4 BPGM PGAM1 | Glycine, serine and threonine metabolism |
| KEGG:00010 | 3.50803627136e-05 | 0.6 | PGAM4 BPGM PGAM1 | Glycolysis / Gluconeogenesis |
| GO:0016868 | 8.06911104389e-05 | 0.6 | PGAM4 BPGM PGAM1 | intramolecular phosphotransferase activity |
| GO:0016866 | 0.00169879277018 | 0.6 | PGAM4 BPGM PGAM1 | intramolecular transferase activity |
| GO:0004082 | 0.00468200720083 | 0.4 | PGAM1 BPGM | bisphosphoglycerate mutase activity |
| KEGG:01230 | 0.00996128881886 | 0.4 | PGAM4 PGAM1 | Biosynthesis of amino acids |
| KEGG:05230 | 0.00996128881886 | 0.4 | PGAM4 PGAM1 | Central carbon metabolism in cancer |
| GO:0004619 | 0.0140440992017 | 0.4 | PGAM4 PGAM1 | phosphoglycerate mutase activity |
| KEGG:04922 | 0.0187947263105 | 0.4 | PGAM4 PGAM1 | Glucagon signaling pathway |
| KEGG:01200 | 0.024008315736 | 0.4 | PGAM4 PGAM1 | Carbon metabolism |
| REAC:R-HSA-70171 | 0.0313469851718 | 0.4 | PGAM1 BPGM | Glycolysis |
| REAC:R-HSA-70326 | 0.0463436196778 | 0.4 | PGAM1 BPGM | Glucose metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PGAM2 | PGAM4 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PGAM1 | BPGM | 0.999 | 0.144 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PGAM2 | PGAM1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| PGAM1 | PGAM4 | 0.997 | 0.2 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| PGAM4 | BPGM | 0.992 | 0.048 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| BPGM | KLF16 | 0.989 | 0.03 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PGAM2 | BPGM | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PGAM2 | SPACA9 | 0.887 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PGAM1 | KLF16 | 0.311 | 0.106 | bioplex_WMM bioplex3_WMM WMM_only |
| PGAM4 | KLF16 | 0.051 | 0.084 | bioplex3_WMM WMM_only |
| PGAM1 | SPACA9 | 0.005 | bioplex3_HEK293 bioplex () bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| PGAM4 | huMAP3_04142.1 huMAP3_11712.1 huMAP3_11905.1 |
| BPGM | huMAP3_04142.1 huMAP3_11712.1 huMAP3_11905.1 |
| PGAM1 | huMAP3_04142.1 huMAP3_11712.1 huMAP3_11905.1 |
| KLF16 | huMAP3_09685.1 huMAP3_11322.1 huMAP3_11712.1 huMAP3_11905.1 huMAP3_12785.1 |
| PGAM2 | huMAP3_04142.1 huMAP3_11712.1 huMAP3_11905.1 |
| SPACA9 | huMAP3_11712.1 huMAP3_12372.1 huMAP3_14311.1 |