hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11725.1
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
POMC | Pro-opiomelanocortin (POMC) (Corticotropin-lipotropin) [Cleaved into: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanocyte-stimulating hormone alpha (Alpha-MSH) (Melanotropin alpha); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanocyte-stimulating hormone beta (Beta-MSH) (Melanotropin beta); Beta-endorphin; Met-enkephalin] | 5 | UniProt   NCBI |
TTL | Tubulin--tyrosine ligase (TTL) (EC 6.3.2.25) | 4 | UniProt   NCBI |
SPMAP2 | Sperm microtubule associated protein 2 (Cancer/testis antigen 56) (CT56) (Testicular haploid expressed gene protein) | 5 | UniProt   NCBI |
MARVELD2 | MARVEL domain-containing protein 2 (Tricellulin) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-5579031 | 0.0499436884912 | 0.25 | POMC | Defective ACTH causes obesity and POMCD |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 TTL |  SPMAP2 | 0.973 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 POMC |  TTL | 0.933 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 MARVELD2 |  TTL | 0.857 |            | bioplex3_HEK293     bioplex ()     |
Related Complexes