hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11741.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CD8B | T-cell surface glycoprotein CD8 beta chain (CD antigen CD8b) | 5 | UniProt NCBI |
| AGTR1 | Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1 receptor) | 5 | UniProt NCBI |
| TMEM11 | Transmembrane protein 11, mitochondrial (Protein PM1) (Protein PMI) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4799 | 0.0136300504448 | 1.0 | AGTR1 | Downregulation of ACE2 by SARS CoV 2 spike protein |
| WP:WP5076 | 0.0181734005931 | 1.0 | AGTR1 | Soluble ACE2 mediated cell entry of SARS CoV 2 |
| WP:WP5133 | 0.0227167507414 | 1.0 | AGTR1 | Non classical role of vitamin D |
| WP:WP4883 | 0.0272601008896 | 1.0 | AGTR1 | SARS CoV 2 and ACE2 receptor molecular mechanisms |
| KEGG:04614 | 0.0321234052737 | 1.0 | AGTR1 | Renin-angiotensin system |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CD8B | TMEM11 | 0.997 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AGTR1 | TMEM11 | 0.93 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| CD8B | huMAP3_03360.1 huMAP3_11741.1 huMAP3_11895.1 huMAP3_13123.1 huMAP3_14443.1 |
| AGTR1 | huMAP3_11741.1 huMAP3_14013.1 |
| TMEM11 | huMAP3_11741.1 huMAP3_14013.1 |