hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11769.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AEN | Apoptosis-enhancing nuclease (EC 3.1.-.-) (Interferon-stimulated 20 kDa exonuclease-like 1) | 5 | UniProt NCBI |
| ACE2 | Angiotensin-converting enzyme 2 (EC 3.4.17.23) (Angiotensin-converting enzyme homolog) (ACEH) (Angiotensin-converting enzyme-related carboxypeptidase) (ACE-related carboxypeptidase) (EC 3.4.17.-) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2] | 5 | UniProt NCBI |
| AAMP | Angio-associated migratory cell protein | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4799 | 0.0248274760036 | 0.333333333333 | ACE2 | Downregulation of ACE2 by SARS CoV 2 spike protein |
| WP:WP5065 | 0.0331010360575 | 0.333333333333 | ACE2 | SARS CoV 2 altering angiogenesis via NRP1 |
| WP:WP5076 | 0.0331010360575 | 0.333333333333 | ACE2 | Soluble ACE2 mediated cell entry of SARS CoV 2 |
| WP:WP5133 | 0.0413734636003 | 0.333333333333 | ACE2 | Non classical role of vitamin D |
| WP:WP4846 | 0.0496447587094 | 0.333333333333 | ACE2 | SARS CoV 2 and COVID 19 pathway |
| WP:WP4853 | 0.0496447587094 | 0.333333333333 | ACE2 | Linoleic acid metabolism affected by SARS CoV 2 |
| WP:WP4883 | 0.0496447587094 | 0.333333333333 | ACE2 | SARS CoV 2 and ACE2 receptor molecular mechanisms |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AEN | AAMP | 0.982 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| AAMP | ACE2 | 0.929 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| AEN | ACE2 | 0.582 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes