hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11795.1
Complex Portal: CPX-15079
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARL5B | ADP-ribosylation factor-like protein 5B (ADP-ribosylation factor-like protein 8) | 4 | UniProt NCBI |
| ARL5A | ADP-ribosylation factor-like protein 5A | 4 | UniProt NCBI |
| FNDC11 | Fibronectin type III domain-containing protein 11 | 5 | UniProt NCBI |
| MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase) | 5 | UniProt NCBI |
| BCL10 | B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CARD-containing molecule enhancing NF-kappa-B) (CARD-like apoptotic protein) (hCLAP) (CED-3/ICH-1 prodomain homologous E10-like regulator) (CIPER) (Cellular homolog of vCARMEN) (cCARMEN) (Cellular-E10) (c-E10) (Mammalian CARD-containing adapter molecule E10) (mE10) | 5 | UniProt NCBI |
| GNAT1 | Guanine nucleotide-binding protein G(t) subunit alpha-1 (Transducin alpha-1 chain) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2753 | 1.36501667663e-05 | 0.4 | MALT1 BCL10 | FYB-CARMA1-BCL-10-MALT1 complex |
| CORUM:2752 | 1.36501667663e-05 | 0.4 | MALT1 BCL10 | CARMA1-BCL10-MALT1 complex |
| CORUM:2053 | 1.36501667663e-05 | 0.4 | MALT1 BCL10 | BCL10-MALT1 complex |
| CORUM:2054 | 8.18785830799e-05 | 0.4 | MALT1 BCL10 | CASP8-FADD-MALT1-BCL10 complex |
| CORUM:2055 | 0.000136445626745 | 0.4 | MALT1 BCL10 | CASP8-CHUK-IKBKB-MALT1-BCL10 complex |
| CORUM:2745 | 0.000136445626745 | 0.4 | MALT1 BCL10 | Ubiquitin E3 ligase (TRAF6, TAB2, MALT1, UEV1A, BCL10) |
| HP:0012123 | 0.000384717178033 | 0.4 | MALT1 BCL10 | Posterior uveitis |
| WP:WP3863 | 0.00687274586933 | 0.4 | MALT1 BCL10 | T cell antigen receptor TCR pathway during Staphylococcus aureus infection |
| HP:0012191 | 0.00768171284681 | 0.4 | MALT1 BCL10 | B-cell lymphoma |
| WP:WP5072 | 0.0080488533074 | 0.4 | MALT1 BCL10 | Modulators of TCR signaling and T cell activation |
| KEGG:04662 | 0.0102617382696 | 0.4 | MALT1 BCL10 | B cell receptor signaling pathway |
| WP:WP69 | 0.010677250915 | 0.4 | MALT1 BCL10 | T cell receptor signaling pathway |
| GO:0032449 | 0.0140440992017 | 0.4 | MALT1 BCL10 | CBM complex |
| KEGG:04064 | 0.0142114773497 | 0.4 | MALT1 BCL10 | NF-kappa B signaling pathway |
| WP:WP5098 | 0.015731077008 | 0.4 | MALT1 BCL10 | T cell activation SARS CoV 2 |
| KEGG:04625 | 0.0160443574347 | 0.4 | MALT1 BCL10 | C-type lectin receptor signaling pathway |
| WP:WP23 | 0.0165943234371 | 0.4 | MALT1 BCL10 | B cell receptor signaling pathway |
| HP:0100721 | 0.0176485923371 | 0.4 | MALT1 BCL10 | Mediastinal lymphadenopathy |
| KEGG:04660 | 0.0235498516465 | 0.4 | MALT1 BCL10 | T cell receptor signaling pathway |
| GO:1903292 | 0.0280843539964 | 0.4 | ARL5A ARL5B | protein localization to Golgi membrane |
| REAC:R-HSA-1169091 | 0.0313469851718 | 0.4 | MALT1 BCL10 | Activation of NF-kappaB in B cells |
| HP:0012539 | 0.0358235710582 | 0.4 | MALT1 BCL10 | Non-Hodgkin lymphoma |
| REAC:R-HSA-1168372 | 0.0406556405791 | 0.4 | MALT1 BCL10 | Downstream signaling events of B Cell Receptor (BCR) |
| REAC:R-HSA-2871837 | 0.0417637628913 | 0.4 | MALT1 BCL10 | FCERI mediated NF-kB activation |
| KEGG:05152 | 0.0471742362289 | 0.4 | MALT1 BCL10 | Tuberculosis |
| HP:0000554 | 0.0472853555832 | 0.4 | MALT1 BCL10 | Uveitis |
| HP:0045026 | 0.0497672375822 | 0.4 | MALT1 BCL10 | Abnormal mediastinum morphology |
| CORUM:2052 | 0.0498708842806 | 0.2 | BCL10 | BCL10 homo-oligomer complex |
| CORUM:2051 | 0.0498708842806 | 0.2 | MALT1 | MALT1 homo-oligomer complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BCL10 | MALT1 | 0.998 | 0.226 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MALT1 | FNDC11 | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| FNDC11 | ARL5B | 0.976 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ARL5B | ARL5A | 0.969 | 0.134 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ARL5B | GNAT1 | 0.823 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MALT1 | ARL5B | 0.232 | 0.08 | bioplex3_WMM WMM_only |
Related Complexes