hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_11798.1

Complex Portal: CPX-20184

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
F9	Coagulation factor IX (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain]	5	UniProt NCBI
FERMT2	Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-9673218	0.0249718442457	0.5	F9	Defective F9 secretion
REAC:R-HSA-9673202	0.0499419797295	0.5	F9	Defective F9 variant does not activate FX
REAC:R-HSA-9672396	0.0499419797295	0.5	F9	Defective cofactor function of FVIIIa variant
REAC:R-HSA-9672383	0.0499419797295	0.5	F9	Defective factor IX causes thrombophilia
REAC:R-HSA-9673240	0.0499419797295	0.5	F9	Defective gamma-carboxylation of F9
HP:0033061	0.0499436884913	0.5	F9	Increased factor IX activity

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
F9	FERMT2	0.983			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM

Related Complexes

Genename	Complexes
F9	huMAP3_00663.1 huMAP3_03151.1 huMAP3_03499.1 huMAP3_05776.1 huMAP3_09814.1 huMAP3_09919.1 huMAP3_11798.1
FERMT2	huMAP3_03499.1 huMAP3_07598.1 huMAP3_08607.1 huMAP3_09502.1 huMAP3_09689.1 huMAP3_11798.1