hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_11801.1

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
ADGRE2	Adhesion G protein-coupled receptor E2 (EGF-like module receptor 2) (EGF-like module-containing mucin-like hormone receptor-like 2) (CD antigen CD312)	5	UniProt NCBI
TSPAN15	Tetraspanin-15 (Tspan-15) (Tetraspan NET-7) (Transmembrane 4 superfamily member 15)	5	UniProt NCBI
TLCD1	TLC domain-containing protein 1 (Calfacilitin)	5	UniProt NCBI
HRH1	Histamine H1 receptor (H1R) (HH1R)	5	UniProt NCBI
TSPAN14	Tetraspanin-14 (Tspan-14) (DC-TM4F2) (Transmembrane 4 superfamily member 14)	5	UniProt NCBI
RIN3	Ras and Rab interactor 3 (Ras interaction/interference protein 3)	5	UniProt NCBI
DMAC1	Distal membrane-arm assembly complex protein 1 (Transmembrane protein 261)	4	UniProt NCBI
SPRY4	Protein sprouty homolog 4 (Spry-4)	5	UniProt NCBI
OCIAD2	OCIA domain-containing protein 2 (Ovarian carcinoma immunoreactive antigen-like protein)	3	UniProt NCBI
SLC22A23	Solute carrier family 22 member 23	5	UniProt NCBI
FZD5	Frizzled-5 (Fz-5) (hFz5) (FzE5)	5	UniProt NCBI
TMT1B	Thiol S-methyltransferase TMT1B (EC 2.1.1.9) (Methyltransferase-like protein 7B) (Thiol S-methyltransferase METTL7B)	5	UniProt NCBI
FZD4	Frizzled-4 (Fz-4) (hFz4) (FzE4) (CD antigen CD344)	5	UniProt NCBI
TMEM54	Transmembrane protein 54 (Beta-casein-like protein) (Protein CAC-1)	5	UniProt NCBI
SNX25	Sorting nexin-25	4	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-5340588	0.00821328967792	0.133333333333	FZD5 FZD4	Signaling by RNF43 mutants
REAC:R-HSA-373080	0.0126091324159	0.2	FZD5 ADGRE2 FZD4	Class B/2 (Secretin family receptors)
REAC:R-HSA-500792	0.0209505030328	0.266666666667	FZD4 FZD5 ADGRE2 HRH1	GPCR ligand binding
REAC:R-HSA-4641263	0.0396807363997	0.133333333333	FZD5 FZD4	Regulation of FZD by ubiquitination

Edges

Protein 1	Protein 2	Score	ProteomeHD
TSPAN15	TMT1B	0.992	0.116
TSPAN15	TMEM54	0.99
TSPAN15	HRH1	0.982
TSPAN15	TSPAN14	0.977	0.142
TSPAN15	DMAC1	0.964	0.154
TSPAN15	SLC22A23	0.963
TSPAN15	SNX25	0.952	0.07
HRH1	TLCD1	0.904
TMEM54	TLCD1	0.904
DMAC1	OCIAD2	0.904	0.028
HRH1	SNX25	0.904
TMEM54	SNX25	0.904
HRH1	TMEM54	0.902
HRH1	DMAC1	0.902
DMAC1	TMEM54	0.902
HRH1	TSPAN14	0.902
RIN3	SPRY4	0.902	0.07
TMEM54	TSPAN14	0.902
HRH1	OCIAD2	0.902
TMEM54	SPRY4	0.902
HRH1	SPRY4	0.902
TMEM54	OCIAD2	0.902
TMEM54	ADGRE2	0.893
HRH1	ADGRE2	0.893
DMAC1	TSPAN14	0.892	0.048
TMEM54	SLC22A23	0.892
HRH1	TMT1B	0.892
HRH1	SLC22A23	0.892
TMEM54	TMT1B	0.892
DMAC1	SPRY4	0.892	0.094
TSPAN15	SPRY4	0.884	0.104
DMAC1	ADGRE2	0.875
TSPAN15	FZD5	0.865
TSPAN15	OCIAD2	0.851	0.184
TSPAN15	TLCD1	0.829	0.092
TSPAN15	FZD4	0.811
TSPAN15	ADGRE2	0.779
SLC22A23	TMT1B	0.742
DMAC1	TLCD1	0.715	0.12
DMAC1	SNX25	0.715	0.07
DMAC1	TMT1B	0.675	0.064
SLC22A23	TSPAN14	0.675
TMT1B	TSPAN14	0.675	0.118
DMAC1	SLC22A23	0.675
TMT1B	OCIAD2	0.633	0.036
SLC22A23	SNX25	0.513
SNX25	TSPAN14	0.49	0.074
SPRY4	OCIAD2	0.468	0.064
OCIAD2	TSPAN14	0.455	0.052
TMT1B	SNX25	0.431	0.072
ADGRE2	OCIAD2	0.427
SPRY4	TSPAN14	0.405	0.072
ADGRE2	TSPAN14	0.401
ADGRE2	SPRY4	0.378
SPRY4	TLCD1	0.356	0.1
ADGRE2	TMT1B	0.356
ADGRE2	SLC22A23	0.356
OCIAD2	TLCD1	0.356	0.04
SPRY4	TMT1B	0.343	0.09
SLC22A23	OCIAD2	0.343
TLCD1	TSPAN14	0.343	0.076
SPRY4	SLC22A23	0.343
OCIAD2	SNX25	0.334	0.034
SPRY4	SNX25	0.334	0.092
SLC22A23	TLCD1	0.323
TMT1B	TLCD1	0.323	0.146
SNX25	TLCD1	0.315	0.108
ADGRE2	TLCD1	0.307
ADGRE2	SNX25	0.22
HRH1	FZD5	0.214
TMEM54	FZD5	0.214
DMAC1	FZD5	0.214
FZD5	OCIAD2	0.146
FZD5	TSPAN14	0.131
ADGRE2	FZD5	0.123
FZD5	SNX25	0.078
FZD5	TMT1B	0.076
SPRY4	FZD5	0.07
FZD5	TLCD1	0.043
FZD5	SLC22A23	0.042

Related Complexes

Genename	Complexes
ADGRE2	huMAP3_00859.1 huMAP3_01740.1 huMAP3_02901.1 huMAP3_05018.1 huMAP3_05469.1 huMAP3_06657.1 huMAP3_07952.1 huMAP3_08737.1 huMAP3_10174.1 huMAP3_10750.1 huMAP3_10990.1 huMAP3_11416.1 huMAP3_11801.1 huMAP3_12613.1 huMAP3_13549.1 huMAP3_14350.1
TSPAN15	huMAP3_00384.1 huMAP3_08599.1 huMAP3_09584.1 huMAP3_10314.1 huMAP3_11801.1
TLCD1	huMAP3_07929.1 huMAP3_08645.1 huMAP3_09611.1 huMAP3_11801.1 huMAP3_12356.1 huMAP3_14859.1
HRH1	huMAP3_00384.1 huMAP3_10314.1 huMAP3_11801.1 huMAP3_12613.1 huMAP3_13549.1 huMAP3_14350.1
TSPAN14	huMAP3_08976.1 huMAP3_09744.1 huMAP3_10376.1 huMAP3_11801.1 huMAP3_12613.1 huMAP3_13549.1 huMAP3_14350.1
RIN3	huMAP3_00447.1 huMAP3_03685.1 huMAP3_05476.1 huMAP3_10709.1 huMAP3_11239.1 huMAP3_11532.1 huMAP3_11633.1 huMAP3_11801.1 huMAP3_12613.1 huMAP3_14042.1 huMAP3_14135.1 huMAP3_14456.1
DMAC1	huMAP3_00384.1 huMAP3_10314.1 huMAP3_11801.1 huMAP3_12613.1 huMAP3_13549.1 huMAP3_14350.1
SPRY4	huMAP3_01882.1 huMAP3_03685.1 huMAP3_06859.1 huMAP3_11239.1 huMAP3_11633.1 huMAP3_11729.1 huMAP3_11801.1 huMAP3_12613.1 huMAP3_14042.1 huMAP3_14350.1
OCIAD2	huMAP3_03623.1 huMAP3_06562.1 huMAP3_07779.1 huMAP3_11801.1 huMAP3_12613.1 huMAP3_13101.1 huMAP3_13533.1 huMAP3_13549.1 huMAP3_14350.1
SLC22A23	huMAP3_03222.1 huMAP3_10152.1 huMAP3_11801.1
FZD5	huMAP3_02182.1 huMAP3_04495.1 huMAP3_05126.1 huMAP3_05865.1 huMAP3_06498.1 huMAP3_07185.1 huMAP3_08162.1 huMAP3_11801.1 huMAP3_13198.1
TMT1B	huMAP3_03407.1 huMAP3_08478.1 huMAP3_10746.1 huMAP3_11801.1
FZD4	huMAP3_11801.1
TMEM54	huMAP3_00384.1 huMAP3_10314.1 huMAP3_11801.1 huMAP3_12613.1 huMAP3_13549.1 huMAP3_14350.1
SNX25	huMAP3_04297.1 huMAP3_04782.1 huMAP3_07507.1 huMAP3_11385.1 huMAP3_11801.1 huMAP3_12230.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_11801.1