hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11822.1
Complex Portal: CPX-16945
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HSD17B1 | 17-beta-hydroxysteroid dehydrogenase type 1 (17-beta-HSD 1) (EC 1.1.1.51) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 1) (EC 1.1.1.62) (Placental 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 1) | 5 | UniProt NCBI |
| SELENOS | Selenoprotein S (SelS) (VCP-interacting membrane protein) | 5 | UniProt NCBI |
| FEZ1 | Fasciculation and elongation protein zeta-1 (Zygin I) (Zygin-1) | 5 | UniProt NCBI |
| KLHDC2 | Kelch domain-containing protein 2 (Hepatocellular carcinoma-associated antigen 33) (Host cell factor homolog LCP) (Host cell factor-like protein 1) (HCLP-1) | 5 | UniProt NCBI |
| AFAP1L1 | Actin filament-associated protein 1-like 1 (AFAP1-like protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6041 | 0.049938562206 | 0.25 | FEZ1 | DISC1-FEZ1 complex |
| CORUM:6043 | 0.049938562206 | 0.25 | FEZ1 | DISC-FEZ1-F-actin complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SELENOS | KLHDC2 | 0.998 | 0.122 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| KLHDC2 | AFAP1L1 | 0.992 | 0.078 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KLHDC2 | FEZ1 | 0.969 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| HSD17B1 | AFAP1L1 | 0.922 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes