hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11837.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNJ10 | ATP-sensitive inward rectifier potassium channel 10 (ATP-dependent inwardly rectifying potassium channel Kir4.1) (Inward rectifier K(+) channel Kir1.2) (Potassium channel, inwardly rectifying subfamily J member 10) | 5 | UniProt NCBI |
| TRPM8 | Transient receptor potential cation channel subfamily M member 8 (Long transient receptor potential channel 6) (LTrpC-6) (LTrpC6) (Transient receptor potential p8) (Trp-p8) | 5 | UniProt NCBI |
| KCNJ11 | ATP-sensitive inward rectifier potassium channel 11 (IKATP) (Inward rectifier K(+) channel Kir6.2) (Potassium channel, inwardly rectifying subfamily J member 11) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296065 | 0.00239054881557 | 0.666666666667 | KCNJ10 KCNJ11 | Inwardly rectifying K+ channels |
| HP:0002717 | 0.00708857159683 | 0.666666666667 | KCNJ10 KCNJ11 | Adrenal overactivity |
| GO:0099094 | 0.00949377645712 | 1.0 | KCNJ10 KCNJ11 TRPM8 | ligand-gated monoatomic cation channel activity |
| GO:0015272 | 0.0140440992017 | 0.666666666667 | KCNJ10 KCNJ11 | ATP-activated inward rectifier potassium channel activity |
| REAC:R-HSA-1296071 | 0.0145828870271 | 0.666666666667 | KCNJ10 KCNJ11 | Potassium Channels |
| GO:0015276 | 0.0180186629002 | 1.0 | KCNJ10 KCNJ11 TRPM8 | ligand-gated monoatomic ion channel activity |
| GO:0022834 | 0.0180186629002 | 1.0 | KCNJ10 KCNJ11 TRPM8 | ligand-gated channel activity |
| HP:0000112 | 0.0418708017344 | 0.666666666667 | KCNJ10 KCNJ11 | Nephropathy |
| REAC:R-HSA-1296067 | 0.0498224659464 | 0.333333333333 | KCNJ10 | Potassium transport channels |
| CORUM:6654 | 0.0499402709677 | 0.333333333333 | KCNJ11 | KCNJ11-ABCC9 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| KCNJ11 | KCNJ10 | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KCNJ11 | TRPM8 | 0.891 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes