hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11838.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AASDH | Beta-alanine-activating enzyme (EC 6.2.1.-) (Acyl-CoA synthetase family member 4) (Protein NRPS998) | 5 | UniProt NCBI |
| GREB1 | Protein GREB1 (Gene regulated in breast cancer 1 protein) | 5 | UniProt NCBI |
| WDR41 | WD repeat-containing protein 41 | 5 | UniProt NCBI |
| KHNYN | Protein KHNYN (KH and NYN domain-containing protein) | 3 | UniProt NCBI |
| TKT | Transketolase (TK) (EC 2.2.1.1) | 5 | UniProt NCBI |
| C9orf72 | Guanine nucleotide exchange factor C9orf72 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7063 | 4.09448956317e-05 | 0.4 | C9orf72 WDR41 | C9orf72-SMCR8-WDR41 complex |
| CORUM:7065 | 0.000286457379015 | 0.4 | C9orf72 WDR41 | WDR41-(C9orf72-SMCR8)-(FIP200-ULK1-ATG13-ATG101) complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TKT | KHNYN | 0.991 | 0.06 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| TKT | AASDH | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TKT | GREB1 | 0.91 | 0.0986666666667 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| C9orf72 | WDR41 | 0.891 | 0.136 | bioplex3_HEK293 bioplex3_WMM gupta_WMM WMM_only |
| TKT | WDR41 | 0.884 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| WDR41 | GREB1 | 0.234 | bioplex_WMM bioplex3_WMM WMM_only | |
| AASDH | WDR41 | 0.187 | bioplex_WMM bioplex3_WMM WMM_only | |
| KHNYN | AASDH | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | |
| AASDH | GREB1 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | |
| KHNYN | GREB1 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | |
| KHNYN | WDR41 | 0.073 | 0.154 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| C9orf72 | TKT | 0.004 | 0.147 | bioplex3_HEK293 WMM_only |
Related Complexes