hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11861.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RHOC | Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9) | 5 | UniProt NCBI |
| C1orf198 | Uncharacterized protein C1orf198 | 3 | UniProt NCBI |
| DAAM1 | Disheveled-associated activator of morphogenesis 1 | 5 | UniProt NCBI |
| CPQ | Carboxypeptidase Q (EC 3.4.17.-) (Lysosomal dipeptidase) (Plasma glutamate carboxypeptidase) | 5 | UniProt NCBI |
| DIAPH2 | Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) | 5 | UniProt NCBI |
| RHOD | Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1) | 5 | UniProt NCBI |
| DIAPH1 | Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5663220 | 4.22297532609e-05 | 0.571428571429 | DIAPH1 DAAM1 RHOC RHOD | RHO GTPases Activate Formins |
| REAC:R-HSA-9012999 | 5.40512105848e-05 | 0.714285714286 | DIAPH1 DAAM1 RHOD RHOC DIAPH2 | RHO GTPase cycle |
| REAC:R-HSA-194315 | 0.000554819347598 | 0.714285714286 | DIAPH1 DAAM1 RHOD RHOC DIAPH2 | Signaling by Rho GTPases |
| REAC:R-HSA-9013106 | 0.000562353197014 | 0.428571428571 | DAAM1 RHOC DIAPH1 | RHOC GTPase cycle |
| REAC:R-HSA-9716542 | 0.000618457686161 | 0.714285714286 | DIAPH1 DAAM1 RHOD RHOC DIAPH2 | Signaling by Rho GTPases, Miro GTPases and RHOBTB3 |
| REAC:R-HSA-195258 | 0.00106596867098 | 0.571428571429 | DIAPH1 DAAM1 RHOC RHOD | RHO GTPase Effectors |
| REAC:R-HSA-9035034 | 0.0325139680435 | 0.285714285714 | DIAPH1 DIAPH2 | RHOF GTPase cycle |
| REAC:R-HSA-9013405 | 0.0480490075434 | 0.285714285714 | DIAPH1 RHOD | RHOD GTPase cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| C1orf198 | RHOD | 0.999 | 0.246 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RHOD | DAAM1 | 0.996 | 0.384 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RHOD | DIAPH2 | 0.996 | 0.210333333333 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| C1orf198 | DAAM1 | 0.995 | 0.184 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| RHOC | DAAM1 | 0.993 | 0.428888888889 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RHOD | DIAPH1 | 0.99 | 0.416 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RHOC | DIAPH1 | 0.884 | 0.224 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| RHOC | C1orf198 | 0.878 | 0.4 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| DIAPH1 | DAAM1 | 0.848 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only |
| CPQ | C1orf198 | 0.832 | 0.084 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| C1orf198 | DIAPH1 | 0.815 | 0.114 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| C1orf198 | DIAPH2 | 0.715 | 0.086 | bioplex3_WMM WMM_only |
| DIAPH1 | DIAPH2 | 0.407 | 0.164 | bioplex3_WMM youn_WMM WMM_only |
| DAAM1 | DIAPH2 | 0.267 | 0.078 | bioplex3_WMM WMM_only |
| CPQ | DAAM1 | 0.193 | 0.064 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes