hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11869.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RABEP2 | Rab GTPase-binding effector protein 2 (Rabaptin-5beta) | 5 | UniProt NCBI |
| RABEP1 | Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17) | 5 | UniProt NCBI |
| SLMAP | Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein) | 5 | UniProt NCBI |
| CEP192 | Centrosomal protein of 192 kDa (Cep192) (Cep192/SPD-2) | 5 | UniProt NCBI |
| CCDC186 | Coiled-coil domain-containing protein 186 (CTCL tumor antigen HD-CL-01/L14-2) | 3 | UniProt NCBI |
| RABGEF1 | Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5) | 5 | UniProt NCBI |
| TAX1BP1 | Tax1-binding protein 1 (TRAF6-binding protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:50 | 6.1565588648e-05 | 0.285714285714 | RABGEF1 RABEP1 | RAB5-RABAPTIN5-RABEX5 complex |
| WP:WP4950 | 0.00575727775656 | 0.285714285714 | RABGEF1 RABEP2 | 16p11 2 distal deletion syndrome |
| REAC:R-HSA-8854214 | 0.028001578843 | 0.285714285714 | RABGEF1 RABEP1 | TBC/RABGAPs |
| KEGG:04137 | 0.047723469919 | 0.285714285714 | RABGEF1 TAX1BP1 | Mitophagy - animal |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RABEP2 | RABGEF1 | 1.0 | 0.192 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 boldt_WMM |
| RABGEF1 | RABEP1 | 0.998 | 0.314 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 boldt_WMM |
| SLMAP | RABEP2 | 0.983 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RABEP2 | RABEP1 | 0.982 | 0.074 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
| RABGEF1 | TAX1BP1 | 0.974 | 0.056 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| SLMAP | RABGEF1 | 0.974 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| CEP192 | RABEP2 | 0.973 | 0.076 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| RABEP1 | CCDC186 | 0.912 | 0.046 | bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only |
| SLMAP | RABEP1 | 0.836 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| SLMAP | CCDC186 | 0.412 | bioplex3_WMM WMM_only | |
| CEP192 | RABGEF1 | 0.302 | 0.108 | bioplex3_WMM youn_WMM WMM_only |
| TAX1BP1 | RABEP1 | 0.213 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only |
| RABEP2 | TAX1BP1 | 0.127 | 0.04 | bioplex_WMM bioplex3_WMM WMM_only |
| SLMAP | CEP192 | 0.09 | bioplex3_WMM youn_WMM WMM_only | |
| SLMAP | TAX1BP1 | 0.089 | bioplex_WMM bioplex3_WMM WMM_only | |
| RABGEF1 | CCDC186 | 0.044 | 0.09 | bioplex3_WMM WMM_only |
| RABEP2 | CCDC186 | 0.022 | 0.056 | bioplex3_WMM WMM_only |
| CEP192 | CCDC186 | 0.014 | 0.154 | youn_WMM WMM_only |
| CEP192 | RABEP1 | 0.01 | 0.138 | youn_WMM gupta_WMM WMM_only |
Related Complexes