hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11894.1
Complex Portal: CPX-15519
Confidence: Medium  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PCDH19 | Protocadherin-19 | 5 | UniProt   NCBI |
| CDON | Cell adhesion molecule-related/down-regulated by oncogenes | 5 | UniProt   NCBI |
| DCHS1 | Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) | 5 | UniProt   NCBI |
| PCDHGB4 | Protocadherin gamma-B4 (PCDH-gamma-B4) (Cadherin-20) (Fibroblast cadherin-2) | 4 | UniProt   NCBI |
| PCDHGB2 | Protocadherin gamma-B2 (PCDH-gamma-B2) | 4 | UniProt   NCBI |
| CELSR3 | Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) | 5 | UniProt   NCBI |
| PCDHGB1 | Protocadherin gamma-B1 (PCDH-gamma-B1) | 4 | UniProt   NCBI |
| OPA3 | Optic atrophy 3 protein | 4 | UniProt   NCBI |
| PCDHGA12 | Protocadherin gamma-A12 (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin-3) | 4 | UniProt   NCBI |
| PCDHGB5 | Protocadherin gamma-B5 (PCDH-gamma-B5) | 4 | UniProt   NCBI |
| PCDHB1 | Protocadherin beta-1 (PCDH-beta-1) | 4 | UniProt   NCBI |
| PCDHGB7 | Protocadherin gamma-B7 (PCDH-gamma-B7) | 4 | UniProt   NCBI |
| PCDHGB3 | Protocadherin gamma-B3 (PCDH-gamma-B3) | 4 | UniProt   NCBI |
| PCDHGB6 | Protocadherin gamma-B6 (PCDH-gamma-B6) | 4 | UniProt   NCBI |
| C18orf32 | UPF0729 protein C18orf32 (Putative NF-kappa-B-activating protein 200) | 4 | UniProt   NCBI |
| PCDH12 | Protocadherin-12 (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cad-2) (VE-cadherin-2) [Cleaved into: Protocadherin-12, secreted form] | 5 | UniProt   NCBI |
| PCDHGA11 | Protocadherin gamma-A11 (PCDH-gamma-A11) | 4 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   GO:0007155 | 4.9816818551e-12 | 0.882352941176 | PCDHGB7 PCDHB1 DCHS1 PCDHGB3 PCDHGA11 PCDH12 PCDHGA12 PCDHGB4 PCDHGB2 PCDHGB6 PCDHGB5 PCDH19 CDON CELSR3 PCDHGB1 | cell adhesion |
|   TF:M10067 | 0.0363011340494 | 0.882352941176 | PCDHB1 PCDHGB4 PCDHGB3 PCDHGA11 PCDH12 PCDHGA12 CDON C18orf32 PCDHGB1 DCHS1 PCDHGB6 PCDHGB5 PCDHGB7 CELSR3 PCDHGB2 | Factor: Sox-2; motif: NNCCTTTGTNYYN |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
|  PCDHGB2 |  PCDHGB7 | 0.998 |            |
structurally_consistent (dimer)        
|
|  PCDHGB2 |  PCDHGB6 | 0.998 |            |
structurally_consistent (dimer)        
|
|  PCDHGB1 |  PCDHGB4 | 0.997 |            |
structurally_consistent (dimer)        
|
|  PCDHGB1 |  PCDHGB2 | 0.997 |            |
structurally_consistent (dimer)        
|
|  PCDHGB3 |  PCDHGB2 | 0.996 |            |
structurally_consistent (dimer)        
|
|  PCDHGB4 |  PCDHGB5 | 0.996 |            |          |
|  PCDH19 |  PCDHGB1 | 0.995 |            |          |
|  PCDHGB1 |  PCDHGB3 | 0.994 |            |
structurally_consistent (dimer)        
|
|  PCDHGB4 |  PCDHGB2 | 0.993 |            |
structurally_consistent (dimer)        
|
|  PCDHGB4 |  PCDHGB3 | 0.992 |            |          |
|  PCDHGB1 |  OPA3 | 0.99 |            |          |
|  PCDHGB2 |  PCDHGA12 | 0.988 |            |
structurally_consistent (dimer)        
|
|  PCDHGB1 |  CDON | 0.983 |            |          |
|  PCDHGB1 |  PCDHGA11 | 0.98 |            |
mutually_exclusive (Q9Y5G2)        
structurally_consistent (dimer)         |
|  PCDHGB2 |  PCDHGB5 | 0.979 |            |
structurally_consistent (dimer)        
|
|  DCHS1 |  PCDHGB1 | 0.979 |            |          |
|  PCDH12 |  CDON | 0.966 |            |          |
|  OPA3 |  PCDHB1 | 0.962 |            |          |
|  PCDHGB3 |  PCDHGB5 | 0.961 |            |          |
|  PCDHGA11 |  CDON | 0.961 |            |          |
|  PCDHGB2 |  PCDHGA11 | 0.959 |            |
mutually_exclusive (Q9Y5G3)        
structurally_consistent (dimer)         |
|  PCDH12 |  PCDHGA11 | 0.956 |            |
structurally_consistent (dimer)        
|
|  PCDHGB1 |  CELSR3 | 0.956 |            |          |
|  PCDHGB1 |  PCDHGA12 | 0.949 |            |
mutually_exclusive (Q9Y5G2)        
|
|  PCDH19 |  PCDH12 | 0.939 |            |          |
|  PCDH19 |  PCDHGB2 | 0.933 |            |          |
|  PCDHGB4 |  PCDHGB7 | 0.931 |            |
mutually_exclusive (Q9Y5G2)        
|
|  PCDHGB3 |  PCDHGB7 | 0.923 |            |
mutually_exclusive (Q9Y5G2)        
|
|  PCDHGB6 |  PCDHB1 | 0.923 |            |
structurally_consistent (dimer)        
|
|  PCDHGB4 |  OPA3 | 0.911 |            |          |
|  PCDHGB4 |  PCDHGB6 | 0.905 |            |
mutually_exclusive (Q9Y5G2)        
|
|  CDON |  C18orf32 | 0.904 |            |          |
|  PCDHGB2 |  OPA3 | 0.876 |            |          |
|  PCDHGB5 |  PCDHGA12 | 0.875 |            |          |
|  PCDHGB5 |  CELSR3 | 0.867 |            |          |
|  PCDHGB6 |  OPA3 | 0.844 |            |          |
|  PCDHGA11 |  PCDHGA12 | 0.84 |            |          |
|  PCDHGA12 |  CDON | 0.833 |            |          |
|  PCDHGB3 |  PCDHGB6 | 0.826 |            |
mutually_exclusive (Q9Y5G2)        
|
|  PCDHGB5 |  PCDHGA11 | 0.796 |            |          |
|  PCDHGB1 |  PCDHGB5 | 0.796 |            |
structurally_consistent (dimer)        
|
|  PCDHGB7 |  PCDHGA11 | 0.796 |            |
mutually_exclusive (Q9Y5G2)        
|
|  PCDHGB6 |  PCDHGA11 | 0.796 |            |
mutually_exclusive (Q9Y5G2)        
|
|  PCDHGB5 |  PCDHGB6 | 0.795 |            |
mutually_exclusive (Q9Y5G2)        
|
|  PCDHGB5 |  PCDHGB7 | 0.795 |            |
mutually_exclusive (Q9Y5G2)        
|
|  PCDHGB3 |  PCDHGA12 | 0.767 |            |          |
|  PCDHGB4 |  PCDHGA12 | 0.767 |            |          |
|  PCDHGB7 |  PCDHGA12 | 0.753 |            |          |
|  PCDHGB7 |  PCDHGB6 | 0.744 |            |
mutually_exclusive (Q9Y5G2)        
|
|  PCDHGB7 |  CDON | 0.715 |            |          |
|  CELSR3 |  PCDHGA11 | 0.682 |            |          |
|  PCDHGB6 |  CDON | 0.675 |            |          |
|  PCDHGB6 |  PCDHGA12 | 0.652 |            |
mutually_exclusive (Q9Y5G2)        
|
|  PCDHGB4 |  CELSR3 | 0.652 |            |          |
|  PCDHGB2 |  CDON | 0.651 |            |          |
|  PCDHGB5 |  OPA3 | 0.643 |            |          |
|  PCDHGB5 |  CDON | 0.613 |            |          |
|  PCDH19 |  CDON | 0.559 |            |          |
|  PCDHGB3 |  OPA3 | 0.559 |            |          |
|  PCDH19 |  PCDHGA12 | 0.529 |            |          |
|  DCHS1 |  PCDHGA11 | 0.454 |            |          |
|  DCHS1 |  CELSR3 | 0.451 | 0.068           |          |
|  PCDHGB3 |  CELSR3 | 0.443 |            |          |
|  DCHS1 |  PCDHGA12 | 0.432 |            |          |
|  PCDH19 |  DCHS1 | 0.428 |            |          |
|  PCDH19 |  PCDHGA11 | 0.35 |            |          |
|  PCDH19 |  CELSR3 | 0.304 |            |          |
|  PCDH19 |  PCDHGB5 | 0.265 |            |          |
|  PCDH19 |  PCDHGB4 | 0.265 |            |          |
|  PCDH19 |  PCDHGB3 | 0.262 |            |          |
|  OPA3 |  PCDHGA12 | 0.258 |            |          |
|  PCDHGB3 |  PCDHGA11 | 0.237 |            |          |
|  PCDH19 |  OPA3 | 0.218 |            |          |
|  PCDHGB4 |  PCDHGA11 | 0.218 |            |          |
|  DCHS1 |  PCDHGB2 | 0.213 |            |          |
|  PCDHGB2 |  CELSR3 | 0.213 |            |          |
|  CELSR3 |  PCDHGA12 | 0.201 |            |          |
|  DCHS1 |  PCDHGB3 | 0.189 |            |          |
|  OPA3 |  CDON | 0.165 |            |          |
|  DCHS1 |  CDON | 0.165 |            |          |
|  DCHS1 |  PCDHGB4 | 0.164 |            |          |
|  DCHS1 |  PCDHGB5 | 0.164 |            |          |
|  OPA3 |  PCDHGA11 | 0.162 |            |          |
|  DCHS1 |  OPA3 | 0.159 | 0.078           |          |
|  CELSR3 |  OPA3 | 0.146 | 0.062           |          |
|  PCDHGB3 |  CDON | 0.143 |            |          |
|  PCDHGB4 |  CDON | 0.143 |            |          |
|  CELSR3 |  CDON | 0.13 |            |          |
|  PCDH19 |  PCDHGB7 | 0.113 |            |          |
|  PCDH19 |  PCDHGB6 | 0.095 |            |          |
|  PCDHGB7 |  OPA3 | 0.078 |            |          |
Related Complexes