List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_11899.1

Confidence: Medium   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
CHP2	Calcineurin B homologous protein 2 (Hepatocellular carcinoma-associated antigen 520)	5	UniProt   NCBI
ITGB3BP	Centromere protein R (CENP-R) (Beta-3-endonexin) (Integrin beta-3-binding protein) (Nuclear receptor-interacting factor 3)	5	UniProt   NCBI
CENPM	Centromere protein M (CENP-M) (Interphase centromere complex protein 39) (Proliferation-associated nuclear element protein 1)	5	UniProt   NCBI
CENPT	Centromere protein T (CENP-T) (Interphase centromere complex protein 22)	5	UniProt   NCBI
CENPQ	Centromere protein Q (CENP-Q)	5	UniProt   NCBI
CENPU	Centromere protein U (CENP-U) (Centromere protein of 50 kDa) (CENP-50) (Interphase centromere complex protein 24) (KSHV latent nuclear antigen-interacting protein 1) (MLF1-interacting protein) (Polo-box-interacting protein 1)	5	UniProt   NCBI
CENPO	Centromere protein O (CENP-O) (Interphase centromere complex protein 36)	5	UniProt   NCBI
CENPK	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33)	5	UniProt   NCBI
MRPS26	Small ribosomal subunit protein mS26 (28S ribosomal protein S13, mitochondrial) (MRP-S13) (S13mt) (28S ribosomal protein S26, mitochondrial) (MRP-S26) (S26mt)	4	UniProt   NCBI
ZFY	Zinc finger Y-chromosomal protein	5	UniProt   NCBI
CENPP	Centromere protein P (CENP-P)	5	UniProt   NCBI
EEIG2	EEIG family member 2 (EEIG2)	2	UniProt   NCBI
CENPI	Centromere protein I (CENP-I) (FSH primary response protein 1) (Follicle-stimulating hormone primary response protein) (Interphase centromere complex protein 19) (Leucine-rich primary response protein 1)	5	UniProt   NCBI
CENPL	Centromere protein L (CENP-L) (Interphase centromere complex protein 33)	5	UniProt   NCBI
CENPH	Centromere protein H (CENP-H) (Interphase centromere complex protein 35)	5	UniProt   NCBI
ZFX	Zinc finger X-chromosomal protein	5	UniProt   NCBI
TBC1D13	TBC1 domain family member 13	4	UniProt   NCBI
CENPW	Centromere protein W (CENP-W) (Cancer-up-regulated gene 2 protein)	5	UniProt   NCBI
CENPN	Centromere protein N (CENP-N) (Interphase centromere complex protein 32)	5	UniProt   NCBI
CENPX	Centromere protein X (CENP-X) (FANCM-associated histone fold protein 2) (FANCM-interacting histone fold protein 2) (Fanconi anemia-associated polypeptide of 10 kDa) (Retinoic acid-inducible gene D9 protein homolog) (Stimulated by retinoic acid gene 13 protein homolog)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0000939	3.01514667242e-37	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	inner kinetochore
CORUM:7394	1.77877305904e-32	0.578947368421	CENPQ CENPH CENPL CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO	CENP-H-I complex
CORUM:1179	1.38604989773e-30	0.578947368421	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPK CENPO CENPL	CENP-A NAC-CAD complex
REAC:R-HSA-774815	3.33874156154e-28	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Nucleosome assembly
REAC:R-HSA-606279	3.33874156154e-28	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Deposition of new CENPA-containing nucleosomes at the centromere
REAC:R-HSA-73886	2.24879601346e-23	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Chromosome Maintenance
GO:0000776	1.14419173638e-20	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	kinetochore
GO:0000779	1.74451291928e-20	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	condensed chromosome, centromeric region
REAC:R-HSA-141424	2.67657841655e-20	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Amplification of signal from the kinetochores
REAC:R-HSA-141444	2.67657841655e-20	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
REAC:R-HSA-69618	2.04257804436e-19	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Mitotic Spindle Checkpoint
REAC:R-HSA-9648025	3.61157042835e-19	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	EML4 and NUDC in mitotic spindle formation
REAC:R-HSA-2500257	8.52296598455e-19	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Resolution of Sister Chromatid Cohesion
GO:0000775	2.08803549202e-18	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	chromosome, centromeric region
REAC:R-HSA-5663220	2.52901811193e-18	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	RHO GTPases Activate Formins
GO:0000793	3.71649745434e-18	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	condensed chromosome
REAC:R-HSA-2467813	1.54314541776e-16	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Separation of Sister Chromatids
REAC:R-HSA-68877	3.14797558782e-16	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Mitotic Prometaphase
REAC:R-HSA-68882	1.62552354152e-15	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Mitotic Anaphase
REAC:R-HSA-2555396	1.71676443871e-15	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Mitotic Metaphase and Anaphase
GO:0098687	2.21125599505e-15	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	chromosomal region
GO:0007059	2.63886531723e-15	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	chromosome segregation
REAC:R-HSA-69620	2.47907147684e-14	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Cell Cycle Checkpoints
REAC:R-HSA-195258	5.07316134992e-14	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	RHO GTPase Effectors
REAC:R-HSA-1640170	2.74637024606e-13	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Cell Cycle
CORUM:929	3.59586306466e-13	0.368421052632	CENPM CENPL CENPU CENPH CENPI CENPK CENPO	CEN complex
CORUM:927	4.79173042039e-13	0.263157894737	CENPN CENPM CENPH CENPT CENPU	CENP-A NAC complex
REAC:R-HSA-68886	1.28163828979e-12	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	M Phase
REAC:R-HSA-69278	5.00632539167e-11	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Cell Cycle, Mitotic
CORUM:7388	6.29483581627e-11	0.263157894737	CENPN CENPI CENPH CENPT CENPL	CENP-A nucleosomal complex
REAC:R-HSA-194315	4.24807681611e-10	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Signaling by Rho GTPases
REAC:R-HSA-9716542	5.50731751689e-10	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Signaling by Rho GTPases, Miro GTPases and RHOBTB3
GO:0099080	2.878943056e-09	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	supramolecular complex
GO:0022402	1.43982209512e-08	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	cell cycle process
GO:0005694	6.34353006821e-08	0.789473684211	CENPQ CENPH CENPT CENPM CENPX CENPW CENPL CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO ZFY	chromosome
CORUM:6146	2.84164363312e-07	0.157894736842	CENPW CENPT CENPX	CENP-T-W-S-X heterotetramer complex
GO:0007049	4.31288968921e-07	0.736842105263	CENPQ CENPH CENPT CENPM CENPX CENPW CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	cell cycle
CORUM:6144	6.11162772017e-05	0.105263157895	CENPW CENPT	CENP-T-W complex
GO:0005654	0.000239777797105	0.894736842105	CENPQ CENPH CENPW CENPT CENPM CENPX CENPP CENPL CENPU MRPS26 ITGB3BP CENPN CENPI CENPK ZFY CENPO CHP2	nucleoplasm
REAC:R-HSA-162582	0.000282400739174	0.631578947368	CENPQ CENPH CENPT CENPM CENPU CENPP ITGB3BP CENPN CENPI CENPK CENPO CENPL	Signal Transduction
GO:0043232	0.000371891268531	0.894736842105	CENPQ CENPH CENPW CENPT CENPM CENPX CENPP CENPL CENPU MRPS26 ITGB3BP CENPN CENPI CENPK ZFY CENPO CHP2	intracellular non-membrane-bounded organelle
GO:0043228	0.000371891268531	0.894736842105	CENPQ CENPH CENPW CENPT CENPM CENPX CENPP CENPL CENPU MRPS26 ITGB3BP CENPN CENPI CENPK ZFY CENPO CHP2	non-membrane-bounded organelle
GO:0031981	0.000690638277052	0.894736842105	CENPQ CENPH CENPW CENPT CENPM CENPX CENPP CENPL CENPU MRPS26 ITGB3BP CENPN CENPI CENPK ZFY CENPO CHP2	nuclear lumen
GO:0070013	0.0227513058361	0.894736842105	CENPQ CENPH CENPW CENPT CENPM CENPX CENPP CENPL CENPU MRPS26 ITGB3BP CENPN CENPI CENPK ZFY CENPO CHP2	intracellular organelle lumen
GO:0043233	0.0227513058361	0.894736842105	CENPQ CENPH CENPW CENPT CENPM CENPX CENPP CENPL CENPU MRPS26 ITGB3BP CENPN CENPI CENPK ZFY CENPO CHP2	organelle lumen
GO:0031974	0.0227513058361	0.894736842105	CENPQ CENPH CENPW CENPT CENPM CENPX CENPP CENPL CENPU MRPS26 ITGB3BP CENPN CENPI CENPK ZFY CENPO CHP2	membrane-enclosed lumen



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
CENPO	CENPP	1.0	0.376
CENPK	CENPH	1.0	0.43
ITGB3BP	CENPP	1.0	0.298
CENPU	ITGB3BP	1.0	0.25
CENPH	CENPI	1.0	0.328
CENPU	CENPQ	1.0	0.524
CENPQ	CENPP	1.0	0.302
CENPO	ITGB3BP	0.999	0.218
CENPU	CENPO	0.999	0.364
CENPU	CENPP	0.999	0.212
CENPO	CENPQ	0.999	0.462
ITGB3BP	CENPQ	0.999	0.302
CENPK	CENPI	0.999	0.206
CENPU	CENPI	0.999	0.268
ITGB3BP	CENPT	0.998	0.156
CENPU	CENPT	0.998	0.19
CENPP	CENPH	0.998	0.284
CENPH	CENPM	0.998	0.26
CENPN	ITGB3BP	0.998	0.21
CENPQ	CENPI	0.998	0.316
CENPN	CENPQ	0.998	0.286
CENPN	CENPI	0.998	0.238
CENPO	CENPT	0.997	0.36
CENPO	CENPI	0.996	0.256
CENPT	CENPQ	0.996	0.172
CENPI	CENPM	0.996	0.138
CENPN	CENPU	0.996	0.322
CENPN	CENPO	0.996	0.38
CENPU	CENPH	0.996	0.194
CENPT	CENPH	0.995	0.26
CENPU	CENPX	0.995	0.168
ITGB3BP	CENPH	0.995	0.196
CENPQ	CENPX	0.994	0.124
CENPO	CENPX	0.994	0.156
CENPN	CENPT	0.993	0.218
ITGB3BP	CENPX	0.993	0.106
CENPK	CENPM	0.993	0.22
CENPO	CENPH	0.993	0.172
ITGB3BP	CENPI	0.993	0.206
CENPQ	CENPH	0.992	0.424
CENPP	CENPX	0.991	0.152
CENPP	CENPI	0.99	0.156
CENPT	CENPI	0.99	0.168
CENPN	CENPH	0.989	0.228
CENPL	CENPQ	0.988	0.176
CENPN	MRPS26	0.987	0.056
CENPN	CENPP	0.985	0.258
TBC1D13	CENPM	0.984	0.054
CENPT	CENPP	0.984	0.138
ZFX	CENPU	0.983	0.138
ZFX	CENPI	0.973	0.108
ZFX	ZFY	0.972
CENPL	CENPI	0.966	0.218
ITGB3BP	CENPK	0.965	0.194
CENPO	CENPK	0.962	0.264
CENPU	CENPK	0.962	0.228
CENPN	CENPL	0.961	0.276
MRPS26	CENPQ	0.961	0.268
MRPS26	EEIG2	0.96	0.024
CENPQ	CENPK	0.96	0.352
CENPQ	CENPM	0.959	0.17
CENPU	CENPL	0.956	0.216
CENPO	CENPM	0.953	0.184
MRPS26	ITGB3BP	0.952	0.198
CENPU	MRPS26	0.952	0.088
MRPS26	CENPO	0.943	0.088
MRPS26	CENPP	0.942	0.124
CENPL	MRPS26	0.938	0.112
CENPL	CENPO	0.938	0.308
CENPL	ITGB3BP	0.931	0.22
ZFX	CENPO	0.925	0.118
MRPS26	CENPT	0.923	0.046
MRPS26	CENPI	0.923	0.116
CENPX	CHP2	0.915
CENPU	CENPM	0.915	0.266
ZFX	CENPN	0.898	0.1
CENPX	CENPH	0.886	0.212
ZFX	ITGB3BP	0.852	0.118
CENPH	CENPW	0.848
ZFX	CENPQ	0.845	0.098
CENPT	CENPW	0.794
CENPN	CENPK	0.785	0.224
CENPP	CENPK	0.785	0.22
CENPN	CENPM	0.785	0.136
CENPT	CENPM	0.785	0.136
CENPP	CENPM	0.785	0.172
ITGB3BP	CENPM	0.785	0.226
CENPT	CENPK	0.785	0.166
CENPL	CENPH	0.765	0.252
CENPX	CENPM	0.764	0.148
CENPN	CENPX	0.764	0.134
CENPX	CENPI	0.764	0.124
CENPX	CENPK	0.764	0.226
CENPT	CENPX	0.764	0.166
MRPS26	CENPH	0.707	0.284
MRPS26	CENPM	0.437	0.102
CENPQ	CENPW	0.423
CENPL	CENPW	0.315
MRPS26	CENPW	0.248
ZFX	CENPT	0.232	0.104
ZFX	CENPP	0.232	0.112
ZFX	CENPX	0.232	0.062
ZFX	CENPM	0.232	0.062
ZFX	CENPK	0.232	0.118
ZFX	CENPH	0.232	0.112
CENPU	CENPW	0.192
CENPP	CENPW	0.192
CENPL	CENPT	0.192	0.16
CENPI	CENPW	0.192
CENPL	CENPX	0.192	0.134
CENPL	CENPK	0.192	0.182
CENPK	CENPW	0.192
ITGB3BP	CENPW	0.192
EEIG2	CENPW	0.192
CENPM	CENPW	0.192
CENPX	CENPW	0.192
CENPL	CENPM	0.192	0.148
CENPN	CENPW	0.192
CENPO	CENPW	0.192
CENPL	EEIG2	0.192	0.096
CENPL	CENPP	0.192	0.294
ZFX	MRPS26	0.152	0.106
ZFX	CENPL	0.135	0.09
CENPH	EEIG2	0.095	0.066
MRPS26	CENPK	0.084	0.054
ZFY	CENPO	0.076
ZFY	CENPQ	0.076
ZFY	MRPS26	0.07
CENPP	EEIG2	0.063	0.054
ITGB3BP	EEIG2	0.063	0.076
MRPS26	CENPX	0.063	0.104
CENPN	EEIG2	0.063	0.106
CENPT	EEIG2	0.063	0.116
EEIG2	CENPM	0.063	0.058
CENPO	EEIG2	0.063	0.096
CENPQ	EEIG2	0.063	0.082
CENPU	ZFY	0.052
CENPX	EEIG2	0.049	0.096
CENPU	EEIG2	0.049	0.09
CENPI	EEIG2	0.049	0.166
CENPK	EEIG2	0.048	0.086





Related Complexes

Genename	Complexes
CHP2	huMAP3_11582.1 huMAP3_11696.1 huMAP3_11899.1 huMAP3_11995.1 huMAP3_12695.1 huMAP3_13031.1 huMAP3_13592.1 huMAP3_14509.1 huMAP3_14808.1 huMAP3_15172.1
ITGB3BP	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPM	huMAP3_09807.1 huMAP3_11899.1 huMAP3_12305.1 huMAP3_13642.1 huMAP3_14808.1
CENPT	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPQ	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPU	huMAP3_01056.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPO	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPK	huMAP3_04427.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
MRPS26	huMAP3_02367.1 huMAP3_05807.1 huMAP3_05954.1 huMAP3_11899.1
ZFY	huMAP3_02155.1 huMAP3_02433.1 huMAP3_04594.1 huMAP3_10388.1 huMAP3_11209.1 huMAP3_11265.1 huMAP3_11899.1 huMAP3_12625.1
CENPP	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
EEIG2	huMAP3_04849.1 huMAP3_11899.1
CENPI	huMAP3_04427.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11265.1 huMAP3_11899.1 huMAP3_14808.1
CENPL	huMAP3_01056.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPH	huMAP3_04427.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_13975.1 huMAP3_14808.1
ZFX	huMAP3_01056.1 huMAP3_02155.1 huMAP3_04594.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11265.1 huMAP3_11899.1 huMAP3_14808.1
TBC1D13	huMAP3_04880.1 huMAP3_11899.1 huMAP3_12305.1 huMAP3_13642.1 huMAP3_14808.1 huMAP3_14813.1
CENPW	huMAP3_11899.1 huMAP3_13975.1 huMAP3_14808.1
CENPN	huMAP3_01056.1 huMAP3_06427.1 huMAP3_09807.1 huMAP3_11899.1 huMAP3_14808.1
CENPX	huMAP3_04053.1 huMAP3_06427.1 huMAP3_09167.1 huMAP3_09780.1 huMAP3_09807.1 huMAP3_09816.1 huMAP3_11696.1 huMAP3_11899.1 huMAP3_12695.1 huMAP3_13031.1 huMAP3_14509.1 huMAP3_14808.1