hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11903.1
Complex Portal: CPX-17537
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MRE11 | Double-strand break repair protein MRE11 (EC 3.1.-.-) (Double-strand break repair protein MRE11A) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A) | 5 | UniProt NCBI |
| AK1 | Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.10) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03450 | 0.0261247873322 | 0.5 | MRE11 | Non-homologous end-joining |
| KEGG:00730 | 0.0284987925806 | 0.5 | AK1 | Thiamine metabolism |
| WP:WP2942 | 0.0435328773163 | 0.5 | MRE11 | DDX1 as a regulatory component of the Drosha microprocessor |
| CORUM:72 | 0.0499419797295 | 0.5 | MRE11 | R/M complex (RAD50-MRE11 complex) |
| CORUM:263 | 0.0499419797295 | 0.5 | MRE11 | R/M complex (RAD50-MRE11 complex) |
| CORUM:264 | 0.0499419797295 | 0.5 | MRE11 | R/M complex (RAD50-MRE11 complex) |
| HP:0100953 | 0.0499436884913 | 0.5 | MRE11 | Enlarged interhemispheric fissure |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MRE11 | AK1 | 0.926 | 0.026 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
Related Complexes
| Genename | Complexes |
|---|---|
| MRE11 | huMAP3_02263.1 huMAP3_04707.1 huMAP3_11272.1 huMAP3_11903.1 huMAP3_14612.1 |
| AK1 | huMAP3_11903.1 huMAP3_13695.1 huMAP3_14442.1 huMAP3_14612.1 huMAP3_14906.1 |