hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11921.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IFNA1 | Interferon alpha-1/13 (IFN-alpha-1/13) (Interferon alpha-D) (LeIF D) | 5 | UniProt NCBI |
| IFNA7 | Interferon alpha-7 (IFN-alpha-7) (Interferon alpha-J) (LeIF J) (Interferon alpha-J1) (IFN-alpha-J1) | 5 | UniProt NCBI |
| IFIT3 | Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G) | 5 | UniProt NCBI |
| IFI44L | Interferon-induced protein 44-like | 4 | UniProt NCBI |
| IFI44 | Interferon-induced protein 44 (p44) (Microtubule-associated protein 44) | 3 | UniProt NCBI |
| ISG15 | Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP) | 5 | UniProt NCBI |
| UBA7 | Ubiquitin-like modifier-activating enzyme 7 (Ubiquitin-activating enzyme 7) (EC 6.2.1.-) (D8) (Ubiquitin-activating enzyme E1 homolog) | 5 | UniProt NCBI |
| IFNA2 | Interferon alpha-2 (IFN-alpha-2) (Interferon alpha-A) (LeIF A) | 5 | UniProt NCBI |
| IFNA4 | Interferon alpha-4 (IFN-alpha-4) (Interferon alpha-4B) (Interferon alpha-76) (Interferon alpha-M1) | 5 | UniProt NCBI |
| IFIT1 | Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56) | 5 | UniProt NCBI |
| IFNA6 | Interferon alpha-6 (IFN-alpha-6) (Interferon alpha-54) (Interferon alpha-K) (LeIF K) | 5 | UniProt NCBI |
| IFNA14 | Interferon alpha-14 (IFN-alpha-14) (Interferon alpha-H) (LeIF H) (Interferon lambda-2-H) | 5 | UniProt NCBI |
| TRIM21 | E3 ubiquitin-protein ligase TRIM21 (EC 2.3.2.27) (52 kDa Ro protein) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (RING finger protein 81) (Ro(SS-A)) (Sjoegren syndrome type A antigen) (SS-A) (Tripartite motif-containing protein 21) | 5 | UniProt NCBI |
| UBR3 | E3 ubiquitin-protein ligase UBR3 (EC 2.3.2.27) (N-recognin-3) (RING-type E3 ubiquitin transferase UBR3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650) | 5 | UniProt NCBI |
| IFNA21 | Interferon alpha-21 (IFN-alpha-21) (Interferon alpha-F) (LeIF F) | 5 | UniProt NCBI |
| IFNA5 | Interferon alpha-5 (IFN-alpha-5) (Interferon alpha-61) (Interferon alpha-G) (LeIF G) | 5 | UniProt NCBI |
| IFNA16 | Interferon alpha-16 (IFN-alpha-16) (Interferon alpha-WA) | 4 | UniProt NCBI |
| IFNA8 | Interferon alpha-8 (IFN-alpha-8) (Interferon alpha-B) (LeIF B) (Interferon alpha-B2) | 5 | UniProt NCBI |
| IFNA17 | Interferon alpha-17 (IFN-alpha-17) (Interferon alpha-88) (Interferon alpha-I') (LeIF I) (Interferon alpha-T) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-909733 | 7.71303227715e-26 | 0.722222222222 | IFNA14 IFIT3 IFNA7 IFNA4 IFNA6 IFNA2 IFIT1 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | Interferon alpha/beta signaling |
| REAC:R-HSA-913531 | 1.9783922203e-24 | 0.833333333333 | IFNA14 IFIT3 IFNA21 IFNA4 IFNA17 IFNA6 IFIT1 IFNA2 IFNA7 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 UBA7 | Interferon Signaling |
| REAC:R-HSA-912694 | 1.256790152e-22 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Regulation of IFNA/IFNB signaling |
| GO:0005132 | 1.43009793195e-22 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | type I interferon receptor binding |
| REAC:R-HSA-168928 | 7.4042062414e-22 | 0.666666666667 | IFNA14 IFNA21 IFNA4 IFNA6 IFNA2 IFNA7 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 UBA7 | DDX58/IFIH1-mediated induction of interferon-alpha/beta |
| GO:0033141 | 7.80668006918e-22 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | positive regulation of peptidyl-serine phosphorylation of STAT protein |
| WP:WP4912 | 1.25963039054e-21 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | SARS coronavirus and innate immunity |
| GO:0009615 | 1.49592391537e-21 | 0.888888888889 | IFNA14 IFIT3 IFNA4 IFNA17 IFI44 IFIT1 IFNA2 IFNA7 IFNA8 ISG15 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA21 | response to virus |
| GO:0033139 | 1.64725583973e-21 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | regulation of peptidyl-serine phosphorylation of STAT protein |
| REAC:R-HSA-933541 | 2.19378357652e-21 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | TRAF6 mediated IRF7 activation |
| GO:0042501 | 3.2928702738e-21 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | serine phosphorylation of STAT protein |
| GO:0043330 | 4.05056539172e-21 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA14 IFIT1 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | response to exogenous dsRNA |
| WP:WP4558 | 7.67735576522e-21 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Overview of interferons mediated signaling pathway |
| KEGG:04622 | 1.0088877636e-20 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | RIG-I-like receptor signaling pathway |
| GO:0043331 | 1.62430771525e-20 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA14 IFIT1 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | response to dsRNA |
| KEGG:05320 | 1.75973729395e-20 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Autoimmune thyroid disease |
| GO:0071357 | 1.85642752682e-20 | 0.666666666667 | IFNA14 IFNA7 IFNA4 IFNA6 IFNA2 IFIT1 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | cellular response to type I interferon |
| WP:WP4655 | 2.02731583703e-20 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | Cytosolic DNA sensing pathway |
| GO:0002323 | 3.48854644054e-20 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | natural killer cell activation involved in immune response |
| GO:0034340 | 4.89416875062e-20 | 0.666666666667 | IFNA14 IFNA7 IFNA4 IFNA6 IFNA2 IFIT1 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | response to type I interferon |
| GO:0060337 | 7.12744139266e-18 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | type I interferon-mediated signaling pathway |
| KEGG:04623 | 8.11309546898e-18 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Cytosolic DNA-sensing pathway |
| REAC:R-HSA-9705671 | 3.03987656896e-17 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | SARS-CoV-2 activates/modulates innate and adaptive immune responses |
| KEGG:05160 | 3.47326982311e-17 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA14 IFIT1 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Hepatitis C |
| KEGG:04620 | 8.11276468384e-17 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Toll-like receptor signaling pathway |
| WP:WP75 | 9.93111199632e-17 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Toll like receptor signaling pathway |
| WP:WP5095 | 1.12675164505e-16 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Overview of proinflammatory and profibrotic mediators |
| GO:0140888 | 2.02614317968e-16 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | interferon-mediated signaling pathway |
| REAC:R-HSA-1280215 | 3.76184642208e-16 | 0.833333333333 | IFNA14 IFIT3 IFNA21 IFNA4 IFNA17 IFNA6 IFIT1 IFNA2 IFNA7 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 UBA7 | Cytokine Signaling in Immune system |
| GO:0098586 | 5.12269892143e-16 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | cellular response to virus |
| GO:0042100 | 6.23321546007e-16 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | B cell proliferation |
| GO:0051707 | 6.32989890204e-16 | 0.944444444444 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFI44 IFIT1 IFNA7 IFNA2 IFNA8 ISG15 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA4 | response to other organism |
| GO:0043207 | 6.32989890204e-16 | 0.944444444444 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFI44 IFIT1 IFNA7 IFNA2 IFNA8 ISG15 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA4 | response to external biotic stimulus |
| KEGG:04650 | 8.55070947487e-16 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Natural killer cell mediated cytotoxicity |
| GO:0009607 | 1.10684393097e-15 | 0.944444444444 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFI44 IFIT1 IFNA7 IFNA2 IFNA8 ISG15 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA4 | response to biotic stimulus |
| KEGG:05169 | 1.26291002182e-15 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | Epstein-Barr virus infection |
| GO:0140546 | 1.68080130655e-15 | 0.888888888889 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFNA6 IFIT1 IFNA2 IFNA7 IFNA8 ISG15 IFNA5 TRIM21 IFI44L IFNA16 IFNA4 | defense response to symbiont |
| GO:0030101 | 2.64104869205e-15 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | natural killer cell activation |
| KEGG:04936 | 3.24817736278e-15 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Alcoholic liver disease |
| KEGG:05162 | 3.24817736278e-15 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Measles |
| KEGG:05171 | 4.60258888893e-15 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | Coronavirus disease - COVID-19 |
| GO:0098542 | 5.7132498802e-15 | 0.888888888889 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFNA6 IFIT1 IFNA2 IFNA7 IFNA8 ISG15 IFNA5 TRIM21 IFI44L IFNA16 IFNA4 | defense response to other organism |
| KEGG:04630 | 5.72105871159e-15 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | JAK-STAT signaling pathway |
| GO:0044419 | 5.94044030693e-15 | 0.944444444444 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFI44 IFIT1 IFNA7 IFNA2 IFNA8 ISG15 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA4 | biological process involved in interspecies interaction between organisms |
| WP:WP4630 | 6.00370324149e-15 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Measles virus infection |
| GO:0033138 | 6.89613114863e-15 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | positive regulation of peptidyl-serine phosphorylation |
| GO:0046425 | 8.02263339151e-15 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | regulation of receptor signaling pathway via JAK-STAT |
| KEGG:04217 | 9.068213979e-15 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Necroptosis |
| REAC:R-HSA-9705683 | 1.07980075363e-14 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | SARS-CoV-2-host interactions |
| GO:0045087 | 1.34880240268e-14 | 0.833333333333 | IFNA14 IFIT3 IFNA21 IFNA4 IFNA17 IFNA6 IFIT1 IFNA2 IFNA7 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 UBA7 | innate immune response |
| GO:1904892 | 1.43737892494e-14 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | regulation of receptor signaling pathway via STAT |
| KEGG:05164 | 1.51244342915e-14 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Influenza A |
| GO:0002286 | 1.65433625205e-14 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | T cell activation involved in immune response |
| KEGG:04621 | 1.74217289764e-14 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | NOD-like receptor signaling pathway |
| KEGG:05152 | 1.74217289764e-14 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Tuberculosis |
| WP:WP4666 | 1.82221793904e-14 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Hepatitis B infection |
| GO:0006955 | 1.97259607931e-14 | 0.944444444444 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFI44 IFIT1 IFNA7 IFNA2 IFNA8 ISG15 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA4 | immune response |
| KEGG:05161 | 2.00278592716e-14 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Hepatitis B |
| GO:0030183 | 3.69658117104e-14 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | B cell differentiation |
| KEGG:05167 | 7.31356314071e-14 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Kaposi sarcoma-associated herpesvirus infection |
| GO:0033135 | 9.84553646527e-14 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | regulation of peptidyl-serine phosphorylation |
| KEGG:05417 | 1.47635337983e-13 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Lipid and atherosclerosis |
| REAC:R-HSA-983231 | 1.92244719102e-13 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Factors involved in megakaryocyte development and platelet production |
| KEGG:05163 | 2.84368304285e-13 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Human cytomegalovirus infection |
| KEGG:05165 | 2.99410597133e-13 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | Human papillomavirus infection |
| KEGG:05170 | 2.99756604971e-13 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Human immunodeficiency virus 1 infection |
| KEGG:04060 | 3.69069863129e-13 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Cytokine-cytokine receptor interaction |
| REAC:R-HSA-9694516 | 6.91521407593e-13 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | SARS-CoV-2 Infection |
| GO:0007259 | 1.15733191869e-12 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | receptor signaling pathway via JAK-STAT |
| GO:0097696 | 1.65389634458e-12 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | receptor signaling pathway via STAT |
| GO:0006952 | 1.78365690699e-12 | 0.888888888889 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFNA6 IFIT1 IFNA2 IFNA7 IFNA8 ISG15 IFNA5 TRIM21 IFI44L IFNA16 IFNA4 | defense response |
| GO:0002285 | 1.96780433217e-12 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | lymphocyte activation involved in immune response |
| GO:0005125 | 5.25885953393e-12 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | cytokine activity |
| GO:0009605 | 1.04133361567e-11 | 0.944444444444 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFI44 IFIT1 IFNA7 IFNA2 IFNA8 ISG15 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA4 | response to external stimulus |
| GO:0042113 | 1.19690142982e-11 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | B cell activation |
| GO:0002376 | 1.32075275308e-11 | 0.944444444444 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFI44 IFIT1 IFNA7 IFNA2 IFNA8 ISG15 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA4 | immune system process |
| KEGG:04151 | 1.57879811365e-11 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | PI3K-Akt signaling pathway |
| WP:WP4172 | 1.84868780477e-11 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | PI3K Akt signaling pathway |
| GO:0034097 | 1.91179996452e-11 | 0.722222222222 | IFNA14 IFNA7 IFNA4 IFNA17 IFNA6 IFNA2 IFIT1 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 IFNA21 | response to cytokine |
| GO:0046651 | 2.23680865549e-11 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | lymphocyte proliferation |
| REAC:R-HSA-9679506 | 2.36352110878e-11 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | SARS-CoV Infections |
| GO:0032943 | 2.73181775608e-11 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | mononuclear cell proliferation |
| GO:0002366 | 3.77876393735e-11 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | leukocyte activation involved in immune response |
| GO:0005126 | 4.86201627226e-11 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | cytokine receptor binding |
| GO:0002263 | 4.86201627226e-11 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | cell activation involved in immune response |
| GO:0006959 | 5.84943702259e-11 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | humoral immune response |
| GO:0018105 | 6.60418430655e-11 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | peptidyl-serine phosphorylation |
| GO:0070661 | 7.44529048097e-11 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | leukocyte proliferation |
| GO:0018209 | 1.25490037286e-10 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | peptidyl-serine modification |
| KEGG:05168 | 1.90046889394e-10 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Herpes simplex virus 1 infection |
| REAC:R-HSA-168249 | 2.8122345662e-10 | 0.722222222222 | IFNA14 IFNA21 IFNA4 IFNA17 IFNA6 IFNA2 IFNA7 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 UBA7 | Innate Immune System |
| GO:0071345 | 3.02536634046e-10 | 0.666666666667 | IFNA14 IFNA7 IFNA4 IFNA6 IFNA2 IFIT1 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | cellular response to cytokine stimulus |
| GO:0002250 | 4.25149446398e-10 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | adaptive immune response |
| GO:0019221 | 9.11148852223e-10 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | cytokine-mediated signaling pathway |
| KEGG:05200 | 1.31110659516e-09 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Pathways in cancer |
| REAC:R-HSA-168256 | 1.45878251992e-09 | 0.833333333333 | IFNA14 IFIT3 IFNA21 IFNA4 IFNA17 IFNA6 IFIT1 IFNA2 IFNA7 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 UBA7 | Immune System |
| GO:0014070 | 1.79741011071e-09 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA14 IFIT1 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | response to organic cyclic compound |
| GO:0030098 | 1.86532993236e-09 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | lymphocyte differentiation |
| GO:1903131 | 6.01352298659e-09 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | mononuclear cell differentiation |
| GO:0048018 | 7.25978983885e-09 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | receptor ligand activity |
| GO:0030546 | 8.41858494083e-09 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | signaling receptor activator activity |
| GO:0030545 | 1.76888757288e-08 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | signaling receptor regulator activity |
| REAC:R-HSA-9824446 | 2.13071050234e-08 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | Viral Infection Pathways |
| GO:0042110 | 3.30833934464e-08 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | T cell activation |
| REAC:R-HSA-109582 | 3.42681686838e-08 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Hemostasis |
| GO:0002521 | 8.24260832412e-08 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | leukocyte differentiation |
| GO:0002252 | 1.29754587005e-07 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | immune effector process |
| GO:1901698 | 1.59476249461e-07 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA14 IFIT1 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | response to nitrogen compound |
| TF:M03575 | 1.65967691564e-07 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Factor: HEN2; motif: CATYTGNNN |
| REAC:R-HSA-5663205 | 1.94015297411e-07 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | Infectious disease |
| TF:M01420_1 | 2.96394301319e-07 | 0.777777777778 | IFNA14 IFIT3 IFNA4 IFNA17 IFI44 IFIT1 IFNA2 IFNA7 IFNA5 IFNA6 TRIM21 IFI44L IFNA8 IFNA21 | Factor: Ncx; motif: NAATNAATTAATAANWW; match class: 1 |
| GO:0001934 | 3.61253967741e-07 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | positive regulation of protein phosphorylation |
| GO:0042327 | 6.01133788849e-07 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | positive regulation of phosphorylation |
| GO:0046649 | 1.01956871443e-06 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | lymphocyte activation |
| GO:0031399 | 1.1137942458e-06 | 0.666666666667 | IFNA7 IFNA4 IFNA17 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 IFNA21 | regulation of protein modification process |
| TF:M08500 | 1.18288915211e-06 | 0.277777777778 | IFNA17 IFNA4 IFNA8 IFNA7 IFNA2 | Factor: HOXB2:ETV7; motif: TAATGRNSMGGAARYRCTTCCGS |
| GO:0045937 | 2.07450476268e-06 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | positive regulation of phosphate metabolic process |
| GO:0010562 | 2.07450476268e-06 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | positive regulation of phosphorus metabolic process |
| GO:0006950 | 2.47260301402e-06 | 0.888888888889 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFNA6 IFIT1 IFNA2 IFNA7 IFNA8 ISG15 IFNA5 TRIM21 IFI44L IFNA16 IFNA4 | response to stress |
| GO:0030097 | 3.94063888891e-06 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | hemopoiesis |
| GO:0045321 | 7.31897288079e-06 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | leukocyte activation |
| GO:0031401 | 8.01119376832e-06 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | positive regulation of protein modification process |
| GO:0018193 | 1.00928877736e-05 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | peptidyl-amino acid modification |
| TF:M08395 | 1.20100587472e-05 | 0.555555555556 | IFNA4 IFNA17 TRIM21 IFNA14 IFNA7 IFNA5 IFI44 IFI44L IFNA16 IFNA21 | Factor: PBX4:HOXA10; motif: NCATAAATCA |
| GO:0010033 | 1.34189788409e-05 | 0.722222222222 | IFNA14 IFNA7 IFNA4 IFNA17 IFNA6 IFNA2 IFIT1 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 IFNA21 | response to organic substance |
| TF:M00672_1 | 1.480698771e-05 | 0.666666666667 | IFNA14 IFNA21 IFNA4 IFNA17 IFI44 IFNA2 IFNA7 IFNA8 IFNA6 IFNA5 IFNA16 UBA7 | Factor: TEF; motif: ATGTTWAYATAA; match class: 1 |
| GO:0071310 | 1.77625480863e-05 | 0.666666666667 | IFNA14 IFNA7 IFNA4 IFNA6 IFNA2 IFIT1 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | cellular response to organic substance |
| GO:0001932 | 2.61184201638e-05 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | regulation of protein phosphorylation |
| GO:0001775 | 3.46024906857e-05 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | cell activation |
| GO:0042325 | 5.12051438184e-05 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | regulation of phosphorylation |
| REAC:R-HSA-1643685 | 5.74650196618e-05 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | Disease |
| GO:0070887 | 5.7936153615e-05 | 0.722222222222 | IFNA14 IFNA7 IFNA4 IFNA17 IFNA6 IFNA2 IFIT1 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 IFNA21 | cellular response to chemical stimulus |
| TF:M12625_1 | 6.19166507981e-05 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Factor: HOXD1; motif: NATYCAKCAN; match class: 1 |
| TF:M04383_1 | 6.73856335108e-05 | 0.722222222222 | IFIT3 IFNA21 IFNA4 IFNA17 IFNA6 IFNA14 IFNA7 UBR3 IFNA8 TRIM21 IFNA5 IFNA16 UBA7 | Factor: LBX2; motif: CTNRANSTAATTA; match class: 1 |
| GO:0140677 | 8.70593175531e-05 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | molecular function activator activity |
| TF:M09952 | 9.58109928684e-05 | 0.5 | IFNA21 IFNA17 IFI44 IFNA14 IFNA7 TRIM21 IFNA5 IFNA16 IFNA4 | Factor: hoxa9; motif: NTGATTTATKR |
| GO:0036211 | 0.000106175691438 | 0.777777777778 | IFNA14 IFNA21 IFNA4 IFNA17 IFNA6 IFNA2 IFNA7 UBR3 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 UBA7 | protein modification process |
| GO:0005102 | 0.000107607182412 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | signaling receptor binding |
| TF:M11909_1 | 0.000138229827984 | 0.555555555556 | IFIT3 IFNA7 IFNA4 IFI44 IFNA2 IFIT1 UBR3 IFNA17 IFNA16 IFNA21 | Factor: POU3F2; motif: NTATGCWAATKAG; match class: 1 |
| TF:M11571_1 | 0.000142424040033 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | Factor: HNF-3alpha; motif: YTRWGTMAATATTTRCWYWN; match class: 1 |
| TF:M04238 | 0.000143828841907 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Factor: FOXD2; motif: NRNWAATATTTAYN |
| TF:M00423_1 | 0.000144797410551 | 0.722222222222 | IFNA14 IFNA7 IFNA4 IFNA17 IFI44 IFNA2 IFIT1 IFNA8 IFNA5 TRIM21 IFI44L IFNA16 IFNA21 | Factor: FOXJ2; motif: AYMATAATATTTKN; match class: 1 |
| TF:M08887_1 | 0.000213644271425 | 0.277777777778 | TRIM21 IFIT3 IFIT1 ISG15 IFI44L | Factor: IRF; motif: NNGAAANTGAAANN; match class: 1 |
| TF:M07058 | 0.000223781823893 | 0.777777777778 | IFIT3 IFNA4 IFNA17 IFI44 IFIT1 IFNA2 IFNA7 UBR3 IFNA8 IFNA5 TRIM21 IFI44L IFNA16 IFNA21 | Factor: POU2F1; motif: ATTTGCATN |
| TF:M07278_1 | 0.000231113684843 | 0.444444444444 | IFNA21 IFNA6 IFNA14 IFNA7 IFI44 IFNA17 IFNA16 IFNA4 | Factor: Dlx-3; motif: NTAATTNVN; match class: 1 |
| GO:0019220 | 0.000249568403252 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | regulation of phosphate metabolic process |
| GO:0051174 | 0.000252690443966 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | regulation of phosphorus metabolic process |
| GO:0043412 | 0.000319775646803 | 0.777777777778 | IFNA14 IFNA21 IFNA4 IFNA17 IFNA6 IFNA2 IFNA7 UBR3 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 UBA7 | macromolecule modification |
| TF:M00795_1 | 0.000342748235707 | 0.5 | IFIT3 IFNA4 IFI44 IFNA2 IFNA7 IFNA17 IFNA5 IFNA16 IFNA21 | Factor: Octamer; motif: TNATTTGCATN; match class: 1 |
| GO:0008283 | 0.000372888430362 | 0.611111111111 | IFIT3 IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | cell population proliferation |
| TF:M07254 | 0.000517768981871 | 1.0 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFI44 IFIT1 IFNA7 IFNA2 UBR3 IFNA8 ISG15 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA4 | Factor: Foxc1; motif: TTVYTTTNW |
| GO:0044877 | 0.000691726882543 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | protein-containing complex binding |
| GO:0051246 | 0.000790406014161 | 0.666666666667 | IFNA7 IFNA4 IFNA17 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 IFNA21 | regulation of protein metabolic process |
| GO:0006468 | 0.000828017587852 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | protein phosphorylation |
| TF:M00802_1 | 0.000867866556346 | 0.5 | IFNA4 IFI44 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA16 IFNA21 | Factor: Pit-1; motif: NMTTCATAAWTATWNMNA; match class: 1 |
| TF:M00161 | 0.000883150682252 | 0.722222222222 | IFNA14 IFIT3 IFNA7 IFNA4 IFNA17 IFI44 IFNA2 IFIT1 UBR3 TRIM21 IFNA5 IFNA16 IFNA21 | Factor: Oct-1; motif: MKVATTTGCATATT |
| TF:M04082_1 | 0.00111822592417 | 0.555555555556 | IFNA21 IFNA17 IFNA6 IFNA14 IFNA7 IFNA8 IFI44 IFNA5 IFNA16 IFNA4 | Factor: POU3F3; motif: WTNAATAWKNAW; match class: 1 |
| TF:M00795 | 0.001170288457 | 0.833333333333 | IFNA14 IFIT3 IFNA4 IFNA17 IFI44 IFIT1 IFNA2 IFNA7 UBR3 IFNA8 IFNA5 TRIM21 IFI44L IFNA16 IFNA21 | Factor: Octamer; motif: TNATTTGCATN |
| GO:0051247 | 0.00119107013 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | positive regulation of protein metabolic process |
| GO:0042221 | 0.00120758013126 | 0.722222222222 | IFNA14 IFNA7 IFNA4 IFNA17 IFNA6 IFNA2 IFIT1 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 IFNA21 | response to chemical |
| TF:M07120_1 | 0.00128051950429 | 0.5 | IFIT3 IFNA4 IFI44 IFNA2 IFNA7 IFNA17 IFNA5 IFNA16 IFNA21 | Factor: Oct-2; motif: NNNATTTGCATRT; match class: 1 |
| TF:M10031_1 | 0.0015232483398 | 0.722222222222 | IFNA14 IFNA4 IFNA17 IFNA6 IFNA2 IFNA7 IFNA8 IFNA5 IFI44 TRIM21 IFI44L IFNA16 IFNA21 | Factor: ipf1; motif: TGATTGATK; match class: 1 |
| TF:M01010_1 | 0.0016082796591 | 0.722222222222 | IFNA14 IFNA4 IFNA17 IFNA6 IFIT1 IFNA7 IFNA8 IFNA5 IFI44 TRIM21 IFI44L IFNA16 IFNA21 | Factor: HMGIY; motif: NNKKNAWTTTNYTNN; match class: 1 |
| TF:M11927 | 0.00164835542025 | 0.611111111111 | IFIT3 IFNA21 IFNA4 IFNA17 IFNA14 IFNA2 IFNA7 IFNA5 IFI44L IFNA16 UBA7 | Factor: POU3F1; motif: TAATKANNNNNTMATTA |
| TF:M00138 | 0.00170168887855 | 0.666666666667 | IFIT3 IFNA7 IFNA4 IFI44 IFNA2 IFIT1 UBR3 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Factor: Oct-1; motif: NNNNNNNWATGCAAATNNNWNNA |
| GO:0016310 | 0.00190515997264 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | phosphorylation |
| TF:M04695 | 0.0026807049421 | 0.5 | IFNA4 IFNA6 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Factor: REST; motif: TTCAGCACCAYGGA |
| TF:M01127 | 0.0028152378035 | 0.333333333333 | IFNA21 IFNA7 IFNA17 IFNA5 IFNA16 IFNA4 | Factor: islet1; motif: GSNTAATRK |
| TF:M00131 | 0.0028744519858 | 0.666666666667 | IFNA14 IFIT3 IFNA21 IFNA4 IFNA17 IFNA6 IFNA2 IFNA7 IFNA5 IFI44L IFNA16 UBA7 | Factor: HNF3beta; motif: KGNANTRTTTRYTTW |
| TF:M12618 | 0.00300667739008 | 0.444444444444 | IFIT3 IFNA21 IFNA6 IFNA14 IFNA2 IFNA5 TRIM21 IFI44L | Factor: HNF1B; motif: GTTAAWCATTAACYNN |
| GO:0051607 | 0.00330804318406 | 0.333333333333 | IFIT3 TRIM21 IFNA2 IFIT1 ISG15 IFI44L | defense response to virus |
| TF:M09957 | 0.00437434391678 | 0.333333333333 | IFIT3 UBA7 TRIM21 IFIT1 ISG15 IFI44 | Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN |
| TF:M10080_1 | 0.0043754188034 | 0.166666666667 | IFIT3 ISG15 IFI44 | Factor: STAT2; motif: RRGRAANNGAAACTGAAAN; match class: 1 |
| TF:M11896_1 | 0.0060181338165 | 0.5 | IFIT3 IFNA4 IFI44 IFNA2 IFNA7 IFNA17 IFNA5 IFNA16 IFNA21 | Factor: Oct-2; motif: NTATGCWAATN; match class: 1 |
| TF:M07362 | 0.00660164243879 | 0.555555555556 | IFNA21 IFNA4 IFNA17 IFI44 IFNA14 IFNA7 IFNA5 IFI44L IFNA16 UBA7 | Factor: nanog; motif: CCATTAAAWNGTK |
| WP:WP4341 | 0.00703076911183 | 0.166666666667 | IFI44L ISG15 IFNA2 | Non genomic actions of 1 25 dihydroxyvitamin D3 |
| TF:M10651 | 0.00859895613558 | 0.555555555556 | IFNA21 IFNA4 IFNA14 IFNA7 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 UBA7 | Factor: HOX11L2; motif: YAATTGNNNNNNNNNCAATTN |
| TF:M11570_1 | 0.00863365954087 | 0.388888888889 | IFNA14 IFNA6 IFNA7 IFNA8 IFNA17 IFNA5 IFNA16 | Factor: HNF-3alpha; motif: CNYTAAGTAAACAAAN; match class: 1 |
| TF:M02026_1 | 0.00970489179217 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA14 IFIT1 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | Factor: MEF-2D; motif: WAAATAR; match class: 1 |
| TF:M11935 | 0.010232359937 | 0.777777777778 | IFIT3 IFNA21 UBA7 IFNA6 IFNA2 IFNA7 UBR3 IFNA8 ISG15 IFNA5 TRIM21 IFI44L IFNA16 IFNA4 | Factor: Oct3; motif: NNWTATGYWAATKANN |
| TF:M11908 | 0.0136619631849 | 0.722222222222 | IFIT3 IFNA21 IFNA4 IFNA17 IFI44 IFIT1 IFNA2 IFNA7 IFNA8 IFNA6 IFNA5 IFNA16 UBA7 | Factor: POU3F2; motif: TAATKAGNNNNTAATKA |
| TF:M04063_1 | 0.0137924702644 | 0.444444444444 | IFNA21 IFNA17 IFNA6 IFNA7 IFI44 IFNA5 IFNA16 IFNA4 | Factor: Pax-4; motif: SWAATWAN; match class: 1 |
| TF:M09629 | 0.0137986346023 | 0.333333333333 | IFIT3 UBA7 TRIM21 IFIT1 ISG15 IFI44 | Factor: IRF-1; motif: NAAANNGAAAGTGAAASTRN |
| TF:M11582_1 | 0.013895281837 | 0.222222222222 | IFNA6 IFNA4 IFNA17 IFNA21 | Factor: FOXI1; motif: AAYRTAAACAAT; match class: 1 |
| TF:M09933_1 | 0.0163555741258 | 0.388888888889 | IFIT3 IFNA21 IFNA6 IFIT1 IFNA7 IFI44 IFNA16 | Factor: FOXP1; motif: TNTGTTTMY; match class: 1 |
| TF:M07453 | 0.0163555741258 | 0.388888888889 | IFNA21 TRIM21 IFNA14 IFNA7 IFNA17 IFNA16 IFNA4 | Factor: Meis1b:Hoxa9:Pbx1a; motif: RTGATTTATGNS |
| GO:0050896 | 0.0198703956426 | 0.944444444444 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFI44 IFIT1 IFNA7 IFNA2 IFNA8 ISG15 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA4 | response to stimulus |
| REAC:R-HSA-1169408 | 0.0211056975049 | 0.166666666667 | IFIT1 ISG15 UBA7 | ISG15 antiviral mechanism |
| TF:M00192_1 | 0.0213371457417 | 0.555555555556 | IFIT3 IFNA4 TRIM21 IFNA14 IFNA7 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 | Factor: GR; motif: NNNNNNCNNTNTGTNCTNN; match class: 1 |
| TF:M04788_1 | 0.0222599970629 | 0.166666666667 | IFIT3 IFIT1 TRIM21 | Factor: IRF-1; motif: STTTCACTTTCNNT; match class: 1 |
| GO:0009966 | 0.0235659595033 | 0.666666666667 | IFNA7 IFNA4 IFNA17 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 TRIM21 IFNA5 IFNA16 IFNA21 | regulation of signal transduction |
| TF:M00972_1 | 0.0270880772413 | 0.277777777778 | TRIM21 IFIT3 IFIT1 ISG15 IFI44 | Factor: IRF; motif: RAAANTGAAAN; match class: 1 |
| REAC:R-HSA-1169410 | 0.0273806632511 | 0.166666666667 | IFIT1 ISG15 UBA7 | Antiviral mechanism by IFN-stimulated genes |
| TF:M12625 | 0.0282736889832 | 0.833333333333 | IFNA14 IFIT3 IFNA4 IFNA17 IFI44 IFIT1 IFNA2 IFNA7 IFNA8 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA21 | Factor: HOXD1; motif: NATYCAKCAN |
| TF:M08394 | 0.0286831704502 | 0.5 | IFNA4 IFNA17 TRIM21 IFNA7 IFNA8 IFI44 IFI44L IFNA16 IFNA21 | Factor: PBX4:HOXA1; motif: NYNATMAATCA |
| TF:M13115 | 0.0288138682184 | 0.388888888889 | IFNA21 IFNA6 IFNA14 IFNA8 IFNA17 IFNA16 IFNA4 | Factor: MBD1; motif: RCTCCAKCYTS |
| WP:WP4197 | 0.0317563381964 | 0.111111111111 | IFIT3 IFIT1 | Immune response to tuberculosis |
| TF:M11927_1 | 0.0371500249503 | 0.444444444444 | IFNA4 IFNA17 IFNA7 IFNA2 IFNA5 IFI44L IFNA16 IFNA21 | Factor: POU3F1; motif: TAATKANNNNNTMATTA; match class: 1 |
| TF:M04514_1 | 0.0375563817828 | 0.444444444444 | IFNA4 IFI44 IFNA14 IFNA7 ISG15 IFNA17 IFNA8 IFNA21 | Factor: CPEB1; motif: AATAAAAA; match class: 1 |
| TF:M00423 | 0.0375798844077 | 0.888888888889 | IFNA14 IFIT3 IFNA21 UBA7 IFNA17 IFI44 IFIT1 IFNA2 IFNA7 IFNA8 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 IFNA4 | Factor: FOXJ2; motif: AYMATAATATTTKN |
| GO:0007166 | 0.0407848561736 | 0.611111111111 | IFNA7 IFNA4 IFNA6 IFNA2 IFNA14 IFNA8 ISG15 IFNA17 IFNA5 IFNA16 IFNA21 | cell surface receptor signaling pathway |
| TF:M00672 | 0.0424035657836 | 0.833333333333 | IFNA14 IFNA21 IFNA4 IFNA17 IFI44 IFNA2 IFNA7 UBR3 IFNA8 IFNA5 IFNA6 TRIM21 IFI44L IFNA16 UBA7 | Factor: TEF; motif: ATGTTWAYATAA |
| GO:0098772 | 0.0472510214022 | 0.555555555556 | IFNA4 IFNA6 IFNA14 IFNA7 IFNA2 IFNA8 IFNA17 IFNA5 IFNA16 IFNA21 | molecular function regulator activity |
| TF:M08836_1 | 0.0478103289909 | 0.388888888889 | IFNA21 IFNA6 IFNA7 IFNA8 IFNA17 IFNA16 IFNA4 | Factor: OCT-2; motif: ATGMATATGCWAAT; match class: 1 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| IFNA5 | IFNA16 | 0.999 | |
| IFNA8 | UBR3 | 0.998 | |
| IFIT1 | IFNA14 | 0.998 | |
| IFNA5 | IFNA14 | 0.998 | |
| IFNA21 | ISG15 | 0.997 | |
| IFNA14 | IFNA1 | 0.996 | |
| IFI44 | IFNA21 | 0.996 | |
| IFNA7 | IFNA4 | 0.995 | |
| IFNA21 | IFNA4 | 0.995 | |
| ISG15 | IFNA14 | 0.995 | |
| IFNA21 | IFNA6 | 0.994 | |
| ISG15 | IFNA1 | 0.994 | |
| IFNA21 | UBR3 | 0.994 | |
| IFNA6 | IFNA1 | 0.993 | |
| IFNA5 | IFNA2 | 0.993 | |
| ISG15 | UBA7 | 0.993 | 0.134 |
| IFI44L | IFNA21 | 0.993 | |
| IFNA8 | IFNA4 | 0.993 | |
| IFNA2 | IFNA4 | 0.992 | |
| ISG15 | IFNA4 | 0.992 | |
| IFNA5 | IFNA6 | 0.992 | |
| IFNA21 | IFNA14 | 0.991 | |
| IFNA21 | IFNA1 | 0.99 | |
| IFNA5 | IFNA17 | 0.989 | |
| IFNA5 | IFNA4 | 0.989 | |
| IFNA2 | ISG15 | 0.989 | |
| IFI44L | IFNA5 | 0.989 | |
| IFNA7 | IFNA16 | 0.989 | |
| TRIM21 | IFNA14 | 0.988 | |
| IFNA7 | ISG15 | 0.987 | |
| IFNA6 | ISG15 | 0.986 | |
| IFNA5 | UBR3 | 0.986 | |
| ISG15 | IFNA16 | 0.982 | |
| IFNA1 | IFNA4 | 0.981 | |
| IFNA5 | ISG15 | 0.979 | |
| IFNA7 | UBR3 | 0.978 | |
| IFNA5 | TRIM21 | 0.976 | |
| IFNA6 | IFNA4 | 0.97 | |
| IFNA6 | IFNA14 | 0.969 | |
| IFIT3 | IFNA14 | 0.967 | |
| ISG15 | UBR3 | 0.966 | 0.098 |
| IFNA17 | IFNA1 | 0.963 | |
| IFNA21 | TRIM21 | 0.958 | |
| IFNA14 | IFNA4 | 0.953 | |
| ISG15 | IFNA8 | 0.942 | |
| TRIM21 | IFNA16 | 0.941 | |
| IFIT1 | IFIT3 | 0.925 | 0.576 |
| IFNA16 | UBR3 | 0.925 | |
| IFNA5 | IFNA1 | 0.917 | |
| TRIM21 | IFNA4 | 0.903 | |
| IFNA6 | TRIM21 | 0.879 | |
| IFNA14 | IFNA16 | 0.868 | |
| IFNA2 | TRIM21 | 0.868 | |
| IFNA6 | IFIT1 | 0.832 | |
| IFNA21 | IFIT3 | 0.817 | |
| ISG15 | IFIT3 | 0.813 | 0.264 |
| ISG15 | IFIT1 | 0.787 | 0.266 |
| IFIT1 | UBR3 | 0.773 | 0.046 |
| ISG15 | TRIM21 | 0.766 | 0.08 |
| TRIM21 | IFNA1 | 0.683 | |
| IFNA1 | IFNA16 | 0.675 | |
| IFNA6 | IFIT3 | 0.668 | |
| IFNA5 | IFIT3 | 0.666 | |
| IFIT1 | IFNA8 | 0.662 | |
| IFNA7 | IFIT1 | 0.661 | |
| IFIT3 | TRIM21 | 0.655 | 0.146 |
| TRIM21 | IFNA8 | 0.628 | |
| IFIT3 | IFNA8 | 0.615 | |
| IFNA6 | UBR3 | 0.612 | |
| IFIT3 | IFNA1 | 0.605 | |
| IFIT1 | IFNA1 | 0.605 | |
| IFIT1 | TRIM21 | 0.592 | 0.122 |
| IFIT3 | UBR3 | 0.586 | 0.034 |
| IFI44 | IFI44L | 0.572 | 0.378 |
| IFI44 | IFNA14 | 0.572 | |
| IFI44 | IFNA1 | 0.543 | |
| IFNA7 | TRIM21 | 0.536 | |
| IFNA7 | IFIT3 | 0.515 | |
| IFI44L | IFNA16 | 0.502 | |
| IFNA2 | IFNA8 | 0.502 | |
| IFNA21 | IFNA8 | 0.502 | |
| IFI44 | IFNA6 | 0.502 | |
| IFI44 | IFNA4 | 0.502 | |
| IFNA7 | IFNA8 | 0.502 | |
| IFNA2 | IFNA7 | 0.502 | |
| IFI44 | IFIT3 | 0.497 | 0.07 |
| IFI44L | IFNA6 | 0.49 | |
| IFI44L | IFNA14 | 0.49 | |
| IFNA8 | IFNA1 | 0.473 | |
| IFI44L | IFNA4 | 0.391 | |
| IFI44L | IFNA1 | 0.391 | |
| IFI44 | IFIT1 | 0.35 | 0.122 |
| TRIM21 | UBR3 | 0.343 | 0.07 |
| IFI44L | IFNA17 | 0.341 | |
| IFNA6 | IFNA16 | 0.333 | |
| IFNA2 | IFNA1 | 0.333 | |
| IFNA21 | IFNA7 | 0.333 | |
| IFNA21 | IFNA2 | 0.333 | |
| IFNA4 | IFNA16 | 0.333 | |
| IFNA7 | IFNA1 | 0.318 | |
| IFNA17 | IFNA4 | 0.3 | |
| IFNA14 | IFNA17 | 0.281 | |
| IFI44L | IFIT1 | 0.281 | 0.134 |
| IFI44L | ISG15 | 0.281 | 0.052 |
| IFI44L | IFIT3 | 0.281 | 0.08 |
| IFIT1 | IFNA4 | 0.281 | |
| IFIT3 | IFNA4 | 0.281 | |
| IFNA6 | IFNA17 | 0.281 | |
| IFNA21 | IFIT1 | 0.277 | |
| ISG15 | IFNA17 | 0.27 | |
| IFNA2 | IFIT3 | 0.247 | |
| IFI44L | TRIM21 | 0.245 | 0.08 |
| IFNA1 | UBR3 | 0.239 | |
| IFNA2 | UBR3 | 0.226 | |
| IFI44L | UBR3 | 0.205 | 0.07 |
| IFIT1 | IFNA16 | 0.202 | |
| IFIT1 | IFNA17 | 0.188 | |
| IFIT3 | IFNA17 | 0.188 | |
| IFI44 | TRIM21 | 0.184 | 0.028 |
| IFNA14 | UBR3 | 0.173 | |
| IFI44 | UBR3 | 0.165 | 0.03 |
| IFIT3 | IFNA16 | 0.15 | |
| IFNA17 | IFNA16 | 0.15 | |
| IFNA21 | IFNA17 | 0.143 | |
| IFI44 | ISG15 | 0.143 | 0.164235294118 |
| TRIM21 | IFNA17 | 0.133 | |
| IFNA4 | UBR3 | 0.13 | |
| IFNA5 | IFIT1 | 0.123 | |
| IFNA17 | UBR3 | 0.056 | |
| UBA7 | TRIM21 | 0.002 | 0.16 |
Related Complexes