hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11930.1
Complex Portal: CPX-18352
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| POMC | Pro-opiomelanocortin (POMC) (Corticotropin-lipotropin) [Cleaved into: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanocyte-stimulating hormone alpha (Alpha-MSH) (Melanotropin alpha); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanocyte-stimulating hormone beta (Beta-MSH) (Melanotropin beta); Beta-endorphin; Met-enkephalin] | 5 | UniProt NCBI |
| TTL | Tubulin--tyrosine ligase (TTL) (EC 6.3.2.25) | 4 | UniProt NCBI |
| SPMAP2 | Sperm microtubule associated protein 2 (Cancer/testis antigen 56) (CT56) (Testicular haploid expressed gene protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5579031 | 0.0498224659464 | 0.333333333333 | POMC | Defective ACTH causes obesity and POMCD |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TTL | SPMAP2 | 0.973 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| POMC | TTL | 0.933 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes