hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11932.1
Complex Portal: CPX-15400
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GSTT2 | Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2) | 4 | UniProt NCBI |
| PDSS1 | All trans-polyprenyl-diphosphate synthase PDSS1 (All-trans-decaprenyl-diphosphate synthase subunit 1) (EC 2.5.1.91) (Decaprenyl pyrophosphate synthase subunit 1) (Decaprenyl-diphosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1) | 5 | UniProt NCBI |
| MCCD1 | Mitochondrial coiled-coil domain protein 1 | 5 | UniProt NCBI |
| LBH | Protein LBH (hLBH) (Limb bud and heart development protein homolog) | 5 | UniProt NCBI |
| THEM4 | Acyl-coenzyme A thioesterase THEM4 (Acyl-CoA thioesterase THEM4) (EC 3.1.2.2) (Carboxyl-terminal modulator protein) (Thioesterase superfamily member 4) | 5 | UniProt NCBI |
| PDSS2 | All trans-polyprenyl-diphosphate synthase PDSS2 (All-trans-decaprenyl-diphosphate synthase subunit 2) (EC 2.5.1.91) (Candidate tumor suppressor protein) (Decaprenyl pyrophosphate synthase subunit 2) (Decaprenyl-diphosphate synthase subunit 2) (Solanesyl-diphosphate synthase subunit 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2142789 | 0.000541723162524 | 0.333333333333 | PDSS1 PDSS2 | Ubiquinol biosynthesis |
| WP:WP5037 | 0.000663806947581 | 0.333333333333 | PDSS1 PDSS2 | Riboflavin and CoQ disorders |
| KEGG:00900 | 0.00167329519289 | 0.333333333333 | PDSS1 PDSS2 | Terpenoid backbone biosynthesis |
| REAC:R-HSA-8978934 | 0.00309047926945 | 0.333333333333 | PDSS1 PDSS2 | Metabolism of cofactors |
| GO:0000010 | 0.00702301080125 | 0.333333333333 | PDSS1 PDSS2 | trans-hexaprenyltranstransferase activity |
| GO:0097269 | 0.00702301080125 | 0.333333333333 | PDSS1 PDSS2 | all-trans-decaprenyl-diphosphate synthase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| THEM4 | GSTT2 | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| THEM4 | LBH | 0.985 | 0.064 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only |
| MCCD1 | PDSS2 | 0.979 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| THEM4 | PDSS2 | 0.974 | 0.106 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MCCD1 | PDSS1 | 0.972 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| PDSS1 | THEM4 | 0.932 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PDSS1 | PDSS2 | 0.744 | 0.106 | bioplex_WMM bioplex3_WMM WMM_only | |
| GSTT2 | PDSS2 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PDSS1 | GSTT2 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes