hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_11936.1

Complex Portal: CPX-24076

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
PCDH19	Protocadherin-19	5	UniProt NCBI
CDON	Cell adhesion molecule-related/down-regulated by oncogenes	5	UniProt NCBI
PCDHGB4	Protocadherin gamma-B4 (PCDH-gamma-B4) (Cadherin-20) (Fibroblast cadherin-2)	4	UniProt NCBI
PCDHGB2	Protocadherin gamma-B2 (PCDH-gamma-B2)	4	UniProt NCBI
CELSR3	Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	5	UniProt NCBI
PCDHGB1	Protocadherin gamma-B1 (PCDH-gamma-B1)	4	UniProt NCBI
OPA3	Optic atrophy 3 protein	4	UniProt NCBI
PCDHGC3	Protocadherin gamma-C3 (PCDH-gamma-C3) (Protocadherin-2) (Protocadherin-43) (PC-43)	4	UniProt NCBI
PCDHB1	Protocadherin beta-1 (PCDH-beta-1)	4	UniProt NCBI
PCDHGB7	Protocadherin gamma-B7 (PCDH-gamma-B7)	4	UniProt NCBI
PCDHGB5	Protocadherin gamma-B5 (PCDH-gamma-B5)	4	UniProt NCBI
PCDHGB3	Protocadherin gamma-B3 (PCDH-gamma-B3)	4	UniProt NCBI
PCDHGB6	Protocadherin gamma-B6 (PCDH-gamma-B6)	4	UniProt NCBI
C18orf32	UPF0729 protein C18orf32 (Putative NF-kappa-B-activating protein 200)	4	UniProt NCBI
PCDH12	Protocadherin-12 (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cad-2) (VE-cadherin-2) [Cleaved into: Protocadherin-12, secreted form]	5	UniProt NCBI
PCDHGA11	Protocadherin gamma-A11 (PCDH-gamma-A11)	4	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0007155	7.11043307956e-11	0.875	PCDHGB5 PCDHGB6 PCDH12 PCDHGA11 PCDHGB1 PCDHGB2 PCDHGB3 PCDHGB4 CELSR3 PCDHGC3 CDON PCDHGB7 PCDHB1 PCDH19	cell adhesion
TF:M10659	0.02446891716	0.5625	PCDHGB5 OPA3 PCDHGB2 PCDHGB4 PCDH19 PCDHGB1 PCDHGC3 PCDHGB7 PCDHGB6	Factor: NKX6-3; motif: SYCATTAWN

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
PCDHGB2	PCDHGB7	0.998		structurally_consistent (dimer)
PCDHGB2	PCDHGB6	0.998		structurally_consistent (dimer)
PCDHGB1	PCDHGB4	0.997		structurally_consistent (dimer)
PCDHGB3	PCDHGC3	0.997		structurally_consistent (dimer)
PCDHGB1	PCDHGB2	0.997		structurally_consistent (dimer)
PCDHGB3	PCDHGB2	0.996		structurally_consistent (dimer)
PCDHGB4	PCDHGB5	0.996
PCDH19	PCDHGB1	0.995
PCDHGB1	PCDHGB3	0.994		structurally_consistent (dimer)
PCDHGB4	PCDHGB2	0.993		structurally_consistent (dimer)
PCDHGB4	PCDHGB3	0.992
PCDHGB1	OPA3	0.99
PCDHGB1	CDON	0.983
PCDHGB1	PCDHGA11	0.98		mutually_exclusive (Q9Y5G2) structurally_consistent (dimer)
PCDHGB2	PCDHGB5	0.979		structurally_consistent (dimer)
PCDH12	CDON	0.966
OPA3	PCDHB1	0.962
PCDHGB3	PCDHGB5	0.961
PCDHGA11	CDON	0.961
PCDHGB1	PCDHGC3	0.961		structurally_consistent (dimer)
PCDHGB2	PCDHGA11	0.959		mutually_exclusive (Q9Y5G3) structurally_consistent (dimer)
PCDH12	PCDHGA11	0.956		structurally_consistent (dimer)
PCDHGB1	CELSR3	0.956
PCDH12	PCDHGC3	0.954		structurally_consistent (dimer)
PCDHGA11	PCDHGC3	0.951
PCDH19	PCDH12	0.939
PCDH19	PCDHGB2	0.933
PCDHGB4	PCDHGB7	0.931		mutually_exclusive (Q9Y5G2)
PCDHGB3	PCDHGB7	0.923		mutually_exclusive (Q9Y5G2)
PCDHGB6	PCDHB1	0.923		structurally_consistent (dimer)
PCDHGB4	OPA3	0.911
PCDHGB4	PCDHGB6	0.905		mutually_exclusive (Q9Y5G2)
CDON	C18orf32	0.904
PCDHGB2	OPA3	0.876
PCDHGB5	CELSR3	0.867
PCDHGB6	OPA3	0.844
PCDHGB3	PCDHGB6	0.826		mutually_exclusive (Q9Y5G2)
PCDHGB2	PCDHGC3	0.824		structurally_consistent (dimer)
PCDHGB5	PCDHGA11	0.796
PCDHGB1	PCDHGB5	0.796		structurally_consistent (dimer)
PCDHGB6	PCDHGA11	0.796		mutually_exclusive (Q9Y5G2)
PCDHGB7	PCDHGA11	0.796		mutually_exclusive (Q9Y5G2)
PCDHGB5	PCDHGB7	0.795		mutually_exclusive (Q9Y5G2)
PCDHGB5	PCDHGB6	0.795		mutually_exclusive (Q9Y5G2)
PCDHGC3	CDON	0.758
PCDHGB7	PCDHGB6	0.744		mutually_exclusive (Q9Y5G2)
PCDHGB7	CDON	0.715
CELSR3	PCDHGA11	0.682
PCDHGB6	CDON	0.675
PCDHGB4	CELSR3	0.652
PCDHGB2	CDON	0.651
PCDHGB5	OPA3	0.643
PCDHGB5	CDON	0.613
PCDHGB3	OPA3	0.559
PCDH19	CDON	0.559
CELSR3	PCDHGC3	0.518	0.102
PCDHGB3	CELSR3	0.443
PCDH19	PCDHGA11	0.35
PCDH19	PCDHGC3	0.328
PCDH19	CELSR3	0.304
PCDH19	PCDHGB4	0.265
PCDH19	PCDHGB5	0.265
PCDH19	PCDHGB3	0.262
PCDHGB3	PCDHGA11	0.237
PCDH19	OPA3	0.218
PCDHGB4	PCDHGA11	0.218
PCDHGB4	PCDHGC3	0.218
PCDHGB2	CELSR3	0.213
OPA3	CDON	0.165
OPA3	PCDHGA11	0.162
OPA3	PCDHGC3	0.162	0.092
PCDHGB5	PCDHGC3	0.151
CELSR3	OPA3	0.146	0.062
PCDHGB3	CDON	0.143
PCDHGB4	CDON	0.143
CELSR3	CDON	0.13
PCDH19	PCDHGB7	0.113
PCDH19	PCDHGB6	0.095
PCDHGB7	PCDHGC3	0.079		mutually_exclusive (Q9Y5G2)
PCDHGB7	OPA3	0.078
PCDHGB6	PCDHGC3	0.076		mutually_exclusive (Q9Y5G2)

Related Complexes

Genename	Complexes
PCDH19	huMAP3_00026.1 huMAP3_07271.1 huMAP3_07751.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12126.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_12701.1 huMAP3_13612.1 huMAP3_13952.1 huMAP3_13974.1 huMAP3_14165.1 huMAP3_15204.1
CDON	huMAP3_07333.1 huMAP3_11558.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_13654.1 huMAP3_13952.1 huMAP3_13968.1 huMAP3_13974.1 huMAP3_15322.1
PCDHGB4	huMAP3_01540.1 huMAP3_01547.1 huMAP3_05300.1 huMAP3_07300.1 huMAP3_09456.1 huMAP3_09591.1 huMAP3_11044.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_12508.1 huMAP3_12589.1 huMAP3_13952.1 huMAP3_13974.1 huMAP3_15067.1 huMAP3_15204.1
PCDHGB2	huMAP3_01540.1 huMAP3_01547.1 huMAP3_03735.1 huMAP3_05794.1 huMAP3_07300.1 huMAP3_08070.1 huMAP3_08211.1 huMAP3_09183.1 huMAP3_09456.1 huMAP3_09591.1 huMAP3_10439.1 huMAP3_11044.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_12508.1 huMAP3_12589.1 huMAP3_12904.1 huMAP3_13663.1 huMAP3_13952.1 huMAP3_13974.1 huMAP3_15067.1 huMAP3_15204.1
CELSR3	huMAP3_02350.1 huMAP3_03659.1 huMAP3_05884.1 huMAP3_06716.1 huMAP3_07751.1 huMAP3_08019.1 huMAP3_09838.1 huMAP3_10576.1 huMAP3_11277.1 huMAP3_11782.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_13952.1 huMAP3_14680.1 huMAP3_15204.1
PCDHGB1	huMAP3_00026.1 huMAP3_07271.1 huMAP3_07751.1 huMAP3_11044.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_13952.1 huMAP3_13974.1 huMAP3_15204.1
OPA3	huMAP3_04520.1 huMAP3_05573.1 huMAP3_10749.1 huMAP3_11648.1 huMAP3_11776.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12155.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_12508.1 huMAP3_13952.1 huMAP3_15067.1
PCDHGC3	huMAP3_06330.1 huMAP3_10002.1 huMAP3_10847.1 huMAP3_11892.1 huMAP3_11936.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_12939.1 huMAP3_13311.1 huMAP3_13952.1 huMAP3_14285.1 huMAP3_15204.1
PCDHB1	huMAP3_04520.1 huMAP3_10749.1 huMAP3_11648.1 huMAP3_11776.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12155.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_13952.1 huMAP3_14866.1 huMAP3_15067.1
PCDHGB7	huMAP3_01547.1 huMAP3_03735.1 huMAP3_05794.1 huMAP3_07370.1 huMAP3_07882.1 huMAP3_08070.1 huMAP3_08227.1 huMAP3_09183.1 huMAP3_09456.1 huMAP3_09591.1 huMAP3_10439.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_12589.1 huMAP3_13974.1 huMAP3_14639.1 huMAP3_14780.1 huMAP3_15067.1 huMAP3_15174.1
PCDHGB5	huMAP3_01547.1 huMAP3_07300.1 huMAP3_09456.1 huMAP3_09591.1 huMAP3_11044.1 huMAP3_11413.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12210.1 huMAP3_12508.1 huMAP3_15204.1
PCDHGB3	huMAP3_01540.1 huMAP3_01547.1 huMAP3_05300.1 huMAP3_07300.1 huMAP3_09456.1 huMAP3_09591.1 huMAP3_11044.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_12508.1 huMAP3_12589.1 huMAP3_13952.1 huMAP3_13974.1 huMAP3_15067.1 huMAP3_15204.1
PCDHGB6	huMAP3_01547.1 huMAP3_03735.1 huMAP3_05794.1 huMAP3_07882.1 huMAP3_08070.1 huMAP3_08227.1 huMAP3_09183.1 huMAP3_09456.1 huMAP3_09591.1 huMAP3_10439.1 huMAP3_11648.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12155.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_12589.1 huMAP3_13952.1 huMAP3_13974.1 huMAP3_15067.1 huMAP3_15174.1 huMAP3_15204.1
C18orf32	huMAP3_11558.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_13654.1 huMAP3_13968.1 huMAP3_13974.1 huMAP3_15322.1
PCDH12	huMAP3_01480.1 huMAP3_04125.1 huMAP3_04252.1 huMAP3_07189.1 huMAP3_08367.1 huMAP3_10002.1 huMAP3_11812.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_12713.1 huMAP3_13612.1 huMAP3_13974.1 huMAP3_15204.1
PCDHGA11	huMAP3_05154.1 huMAP3_05425.1 huMAP3_07333.1 huMAP3_07918.1 huMAP3_10002.1 huMAP3_10622.1 huMAP3_11892.1 huMAP3_11894.1 huMAP3_11936.1 huMAP3_12210.1 huMAP3_12330.1 huMAP3_12422.1 huMAP3_13952.1 huMAP3_13974.1 huMAP3_15204.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_11936.1

Complex Portal: CPX-24076