hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11943.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IL2RA | Interleukin-2 receptor subunit alpha (IL-2 receptor subunit alpha) (IL-2-RA) (IL-2R subunit alpha) (IL2-RA) (TAC antigen) (p55) (CD antigen CD25) | 5 | UniProt NCBI |
| SLC46A1 | Proton-coupled folate transporter (HsPCFT) (hPCFT) (Heme carrier protein 1) (PCFT/HCP1) (Solute carrier family 46 member 1) | 5 | UniProt NCBI |
| ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha-2 (Na(+)/K(+) ATPase alpha-2 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04978 | 0.000823509653423 | 0.666666666667 | SLC46A1 ATP1A2 | Mineral absorption |
| HP:0002014 | 0.00477365029946 | 1.0 | IL2RA ATP1A2 SLC46A1 | Diarrhea |
| HPA:0091042 | 0.0195167913168 | 0.666666666667 | IL2RA ATP1A2 | cerebellum; processes in white matter[>=Medium] |
| HPA:0091041 | 0.0262976640836 | 0.666666666667 | IL2RA ATP1A2 | cerebellum; processes in white matter[>=Low] |
| CORUM:1707 | 0.0499402709677 | 0.333333333333 | IL2RA | IL2-IL2RA-IL2RB complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ATP1A2 | IL2RA | 0.933 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| IL2RA | SLC46A1 | 0.803 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ATP1A2 | SLC46A1 | 0.068 | 0.084 | bioplex3_WMM WMM_only |
Related Complexes